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7 951 (0,104s) •

Project

Inhibition effect of Protein S in deep-venou s trombosis (IZ4072)

In Patiens with Resistence to activate Protein C and low levels of Protein S correlation of free and bound protein S and genomic defect will be performed.......

FP - Ostatní lékařské obory

  • 1997 - 1999
    • •
  • 4 771 tis. Kč
    • •
  • 3 927 tis. Kč
    • •
  • MZ
Project

Clinical Use of the Assessment of S100B Protein and Neuron Specific Enolase Levels at Early Stage of CNS Damage (NR7874)

The basis of the research is the monitoring of the dynamics in S100B protein and NSE levels at an early stage of CNS damage. The aim is to evaluate possibilities of the assessment of the current condition in patients whose general c...

FH - Neurologie, neurochirurgie, neurovědy

  • 2004 - 2006
    • •
  • 2 324 tis. Kč
    • •
  • 2 247 tis. Kč
    • •
  • MZ
Project

A novel panel of proteins associated with lymph node status in low-grade breast cancer Clinical verification and role in tumor cell invasiveness (GA14-19250S)

in lymph nodes. The relationships between protein level and migration/invasivity will be characterized at cellular level. Functional and protein-protein interactions studies, we have identified a panel of...

CE - Biochemie

  • 2014 - 2016
    • •
  • 7 968 tis. Kč
    • •
  • 7 968 tis. Kč
    • •
  • GA ČR
Project

Super resolution (single molecule fluorescent) microscopy for detecting interactions between membrane proteins present at low level (8J22AT012)

1) Develop a method allowing to detect interactions of membrane proteins at the single molecule level. 2) To analyse the multimeric state of S. cerevisiae membrane proteins Trk1/2 and Kch1/2 which are involved in cation ho...

Cell biology

  • 2022 - 2023
    • •
  • 144 tis. Kč
    • •
  • 144 tis. Kč
    • •
  • MŠMT
Project

Genomic analysis of galactose transport protein degradation in the yeast Saccharomyces cerevisiae (GA204/05/2578)

at the level oftranscription and at tne posttranslational leveí. At the posttranslational level glucose decreases the activity and stability of the enzymes of gluconeogenesis and of several sugar-specific transport proteins

EB - Genetika a molekulární biologie

  • 2005 - 2007
    • •
  • 1 417 tis. Kč
    • •
  • 1 417 tis. Kč
    • •
  • GA ČR
Project

Optical imaging of single protein dynamics (LL1602)

and tracking the conformational dynamics of proteins at a single-molecular level the conformations of a protein in its native environment is a crucial step in revealing its biological function. We advance the proven concep...

CF - Fyzikální chemie a teoretická chemie

  • 2016 - 2021
    • •
  • 40 738 tis. Kč
    • •
  • 40 738 tis. Kč
    • •
  • MŠMT
Project

p63 and p73 proteins as predictive markers in clinical oncology. (NT14602)

. In the tumor biopsies, we will analyze the expression of p63 and p73 on the mRNA level by qRT-PCR and on the protein level by immunohistochemical staining (IHC of patients. Simultaneously, we will determine the expression...

FD - Onkologie a hematologie

  • 2013 - 2015
    • •
  • 4 961 tis. Kč
    • •
  • 4 961 tis. Kč
    • •
  • MZ
Project

Mechanisms of iron absorption and characterization of proteins involved. Funkction of the protein HFE coded by the gene mutated in hereditary hemochomatosis (NB6574)

for the identification of the protein by database searching and/or for the cDNA cloning. We will construct the intestinal cell line expressing different levels of the HFE protein under will describe the intracellular iron ...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 4 777 tis. Kč
    • •
  • 4 543 tis. Kč
    • •
  • MZ
Project

Analysis of the role of cytokinins in the regulation of leaf senescence and N mobilization in genetically modified cereals and recombinant substitution lines with improved grain protein content (7AMB13AR014)

with altered metabolism for increased grain protein content and improvement such as induced senescence, pharmacological treatment and determination of various N levels effect on selected plant models and cereals with improved grain...

CE - Biochemie

  • 2013 - 2014
    • •
  • 320 tis. Kč
    • •
  • 320 tis. Kč
    • •
  • MŠMT
Project

Analysis of the effects of cold and drought on stress tolerance with respect to proteome changes in wheat genotypes with different tolerance levels (GPP501/11/P637)

by evaluationof parameters which correlate with the tolerance level (accumulation of stress-inducible proteins). Acclimation is associated with changes in gene expression which are mirrored at protein level. Diffe...

GE - Šlechtění rostlin

  • 2011 - 2013
    • •
  • 1 464 tis. Kč
    • •
  • 1 464 tis. Kč
    • •
  • GA ČR
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