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6 064 (0,256s) •

Project

Novel Tools for Cell Cycle Analysis (TA03010719)

The determination of the cell proliferation activity is a basic methodological approach for the evaluation of the cell population conditions in many situations e.g. in the evaluation of the genotoxicity or in the analysis of the effect of agents with...

EI - Biotechnologie a bionika

  • 2013 - 2015
    • •
  • 9 600 tis. Kč
    • •
  • 6 000 tis. Kč
    • •
  • TA ČR
Project

Nucleophilic and radical tetrafluoroethyl and tetrafluoroethylene group transfer. (GAP207/11/0421)

We propose to synthesize four new fluorinated sulfur-containing reagents: (2-bromo-1,1,2,2-tetrafluoro-ethylsulfanyl)-benzene (PhSCF2CF2Br), trimethyl-(1,1,2,2-tetrafluoro-2-phenylsulfanyl-ethyl)-silane (PhSCF2CF2SiMe3), (<...

CC - Organická chemie

  • 2011 - 2013
    • •
  • 1 791 tis. Kč
    • •
  • 1 791 tis. Kč
    • •
  • GA ČR
Project

Phosphonate-based 2'-5' oligoadenylate analogs a novel metabolically stable potential activators of RNase L. (IAA4055101)

diverse phosphonate 2',5'-oligoadenylate (2-5A) analogs as potential activators the solid-phase synthesis of 2-5A analogs, the spontaneous heavy metal-catalysed will be investigated and checked by LC-MS. The desig...

CC - Organická chemie

  • 2001 - 2005
    • •
  • 15 202 tis. Kč
    • •
  • 4 405 tis. Kč
    • •
  • AV ČR
Project

Bioorthogonal time-controlled intramitochondrial elimination (GF20-30494L)

of achieving highly selective incorporation of ethynyl deoxyuridine (EdU...

Organic chemistry

  • 2020 - 2022
    • •
  • 8 156 tis. Kč
    • •
  • 7 933 tis. Kč
    • •
  • GA ČR
Project

Novel DNA and RNA oligonucleotides with Phosphonothioate and Phosphonoamidate Internucleotide Linkages. (GA13-26526S)

of 2-5A system - agonists/antagonists of RNase L (2',5'-oligoriboadenylates) and inhibitors of the 2',5'-specific phosphodiesterase. A key part of the project......

CC - Organická chemie

  • 2013 - 2016
    • •
  • 11 970 tis. Kč
    • •
  • 11 970 tis. Kč
    • •
  • GA ČR
Project

Complex liposomal forms of photosentitizers for experimental photodynamic therapy of tumors (NR7778)

in liposomes with additions of antineoplstics like 3-bromo-pyruvic acid or cisplatin...

FD - Onkologie a hematologie

  • 2004 - 2009
    • •
  • 8 383 tis. Kč
    • •
  • 4 651 tis. Kč
    • •
  • MZ
Project

Effect of strict glycemic control and early ravascularization on 5-year mortality of patients with diabetes mellitus type 1 and coronary artery dis. (NA5335)

Coronary artery disease (CAD) is the main cause of mortality and morbodity of patients with diabetes mellitus type 2 (DM2). The aim of the study is to evaluatethe effect of strict glycemic control and early revascularization on 5 ye...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 1999 - 2006
    • •
  • 1 662 tis. Kč
    • •
  • 1 662 tis. Kč
    • •
  • MZ
Project

Intermediates for non-ionic X-ray contrast media - application of principles of Green Chemistry (TA01010606)

The project aim is to develop and validate new technology for production of 5-nitroisophthalic acid, 5-amino-2,4,6-triiodoisophthalic acid and/or for production of other advanced intermediates, which can be used as the X-ray contras...

CC - Organická chemie

  • 2011 - 2013
    • •
  • 14 584 tis. Kč
    • •
  • 9 460 tis. Kč
    • •
  • TA ČR
Project

Metallic ribbons for magnetic sensors (7AMB12SK027)

noise 2)detailed characterisation of the selected materials - magnetic, mechanical for Eurosensors 2012 conference 5)analysis of the magnetization process in the core and nanocrystalline materials for fluxgate sensors 2) a...

JB - Senzory, čidla, měření a regulace

  • 2012 - 2013
    • •
  • 96 tis. Kč
    • •
  • 96 tis. Kč
    • •
  • MŠMT
Project

Study of isotopic exchange of hydrogen in the position 5 of pyrimidine derivatives and synthesis of pyrimidines with biological activity labeled with tritium. (KJB400550903)

of pyrimidine derivatives with various substituents in positions 2, 4 and 6 will be prepared and isotopic exchange of hydrogen in the position 5 of the pyrimidine ring will be studied by 1H NMR spectroscopy in D2O (the intensity of...

CC - Organická chemie

  • 2009 - 2011
    • •
  • 910 tis. Kč
    • •
  • 910 tis. Kč
    • •
  • AV ČR
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