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6 066 (0,467s) •

Project

Novel Tools for Cell Cycle Analysis (TA03010719)

The determination of the cell proliferation activity is a basic methodological approach for the evaluation of the cell population conditions in many situations e.g. in the evaluation of the genotoxicity or in the analysis of the effect of agents with...

EI - Biotechnologie a bionika

  • 2013 - 2015
    • •
  • 9 600 tis. Kč
    • •
  • 6 000 tis. Kč
    • •
  • TA ČR
Project

The impact of cytidine metabolic pathways on cytarabine therapy of hematological malignancies and new diagnostic tools for their analysis (NU22-08-00148)

Cytidine deaminase (CDA) and deoxycytidine monophosphate deaminase (DCTD), deoxycytidine kinase (dCK), 5'-nucleotidase and human equilibrative nucleoside transporter (hENT1) participate in the regulation of cellular nucleot...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2022 - 2025
    • •
  • 10 318 tis. Kč
    • •
  • 10 318 tis. Kč
    • •
  • MZ
Project

Development of a proces for manufacturing of tailor made Cu/Bi catalyst for ethynylation reaction (7D15007)

Development of a proces for manufacturing of tailor made Cu/Bi catalyst for ethynylation reaction...

CA - Anorganická chemie

  • 2016 - 2017
    • •
  • 9 775 tis. Kč
    • •
  • 5 618 tis. Kč
    • •
  • MŠMT
Project

Polyacetylene type microporous polymers for applications in heterogeneous catalysis. (GA17-03474S)

with non-reacted ethynyl groups serving either as acid catalytic centres or precursors will result by polymerization of Cu, Co, Mn and Mo complexes with ethynylated N......

CD - Makromolekulární chemie

  • 2017 - 2019
    • •
  • 7 993 tis. Kč
    • •
  • 7 227 tis. Kč
    • •
  • GA ČR
Project

Interpenetrating polyacetylene based polymeric networks prepared by "click" chemistry (GA203/09/0803)

groups (ethynyl/azide) will be introduced to these polymers either via), polynornornene, polythiophene) or low MW functional group bearing derivatives using 2+3......

CD - Makromolekulární chemie

  • 2009 - 2011
    • •
  • 2 026 tis. Kč
    • •
  • 2 026 tis. Kč
    • •
  • GA ČR
Project

Phosphonate-based 2'-5' oligoadenylate analogs a novel metabolically stable potential activators of RNase L. (IAA4055101)

diverse phosphonate 2',5'-oligoadenylate (2-5A) analogs as potential activators the solid-phase synthesis of 2-5A analogs, the spontaneous heavy metal-catalysed will be investigated and checked by LC-MS. The desig...

CC - Organická chemie

  • 2001 - 2005
    • •
  • 15 202 tis. Kč
    • •
  • 4 405 tis. Kč
    • •
  • AV ČR
Project

Rigid cyclodextrin duplexes synthesis and study of inclusion complexes (GA203/06/1550)

The proposal deals with the synthesis of rigid dimers composed of +-cyclodextrin units bridged at 6A - 6'A' and 6D - 6'D positions. First, methods allowing synthesis of selectively difunctionalized cyclodextrins bearing iodo-, thio-, carboxy-, formyl...

CC - Organická chemie

  • 2006 - 2008
    • •
  • 1 161 tis. Kč
    • •
  • 1 161 tis. Kč
    • •
  • GA ČR
Project

Novel DNA and RNA oligonucleotides with Phosphonothioate and Phosphonoamidate Internucleotide Linkages. (GA13-26526S)

of 2-5A system - agonists/antagonists of RNase L (2',5'-oligoriboadenylates) and inhibitors of the 2',5'-specific phosphodiesterase. A key part of the project......

CC - Organická chemie

  • 2013 - 2016
    • •
  • 11 970 tis. Kč
    • •
  • 11 970 tis. Kč
    • •
  • GA ČR
Project

Effect of strict glycemic control and early ravascularization on 5-year mortality of patients with diabetes mellitus type 1 and coronary artery dis. (NA5335)

Coronary artery disease (CAD) is the main cause of mortality and morbodity of patients with diabetes mellitus type 2 (DM2). The aim of the study is to evaluatethe effect of strict glycemic control and early revascularization on 5 ye...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 1999 - 2006
    • •
  • 1 662 tis. Kč
    • •
  • 1 662 tis. Kč
    • •
  • MZ
Project

Intermediates for non-ionic X-ray contrast media - application of principles of Green Chemistry (TA01010606)

The project aim is to develop and validate new technology for production of 5-nitroisophthalic acid, 5-amino-2,4,6-triiodoisophthalic acid and/or for production of other advanced intermediates, which can be used as the X-ray contras...

CC - Organická chemie

  • 2011 - 2013
    • •
  • 14 584 tis. Kč
    • •
  • 9 460 tis. Kč
    • •
  • TA ČR
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