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64 (0,061s) •

Project

Alternative pathway of cytokinin catabolism (GA522/06/0022)

of these compounds is via adenine deaminase (EC 3.5.4.2) that hydrolytically converts adenine to hypoxanthine, or AMP deaminase (EC 3.5.4.6) that converts AMP to IMP. These are few......

EB - Genetika a molekulární biologie

  • 2006 - 2008
    • •
  • 3 132 tis. Kč
    • •
  • 3 132 tis. Kč
    • •
  • GA ČR
Project

Adenosine deaminase homologs in Drosophila (IAA5007107)

Members of the ADA (adenosine deaminase) gene family, which include ADA and CECR1 (cat eye syndrome critical region 1), cause severe congenital disorders in humans, however, the exact physiological role of these genes is not known. To gain, ...

EB - Genetika a molekulární biologie

  • 2001 - 2005
    • •
  • 3 878 tis. Kč
    • •
  • 1 998 tis. Kč
    • •
  • AV ČR
Project

Use of antimicrobial peptides to treatment of musculoskeletal infections with the help of local carriers used in orthopedics (NT14218)

diseases. Local application of antimicrobial peptides (AMPs) released from local carriers seems to be very promising therapeutic method. Because AMPs kill microbes to,or substitute for, conventional antibiotics. Recent discoveries ...

FI - Traumatologie a ortopedie

  • 2013 - 2014
    • •
  • 1 371 tis. Kč
    • •
  • 1 371 tis. Kč
    • •
  • MZ
Project

Targets and consequences of activation-induced cytidine deaminase-mediated mutagenesis in tumours (GN24-11338I)

Activation-induced cytidine deaminase (AID) causes mutations in immunoglobulin genes of activated B cells and is required for the production of high-affinity antibodies. However, AID also causes mutations in non-immunoglobulin genes, contrib...

Cell biology

  • 2024 - 2027
    • •
  • 6 323 tis. Kč
    • •
  • 6 323 tis. Kč
    • •
  • GA ČR
Project

Induction of antimicrobial peptides in Salmonella-caused gastroenteritis in dependence on type of lipopolysacharide (ME 915)

response will be elucidated by the assessment of antimicrobial peptides (AMP) in differentparts of the gut by real time PCR. Aim 1 AMP will be measured by real time PCR in the jejunum, ileum and colon. Aim 2 AMP response w...

EC - Imunologie

  • 2007 - 2011
    • •
  • 1 794 tis. Kč
    • •
  • 1 794 tis. Kč
    • •
  • MŠMT
Project

The impact of cytidine metabolic pathways on cytarabine therapy of hematological malignancies and new diagnostic tools for their analysis (NU22-08-00148)

Cytidine deaminase (CDA) and deoxycytidine monophosphate deaminase (DCTD), deoxycytidine kinase (dCK), 5'-nucleotidase and human equilibrative nucleoside transporter (hENT1) participate in the regulation of cellular nucleotide and n...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2022 - 2025
    • •
  • 10 318 tis. Kč
    • •
  • 10 318 tis. Kč
    • •
  • MZ
Project

Chromosomal rearrangements with breakpoints in T cell receptor genes (GAP502/12/1966)

and sequencing. Percentages of γδ T-cells in peripheral blood lymphocytes to test the hypothesis that frequencies of trans-rearrangementsare higher in γδ T-cells than in &

EB - Genetika a molekulární biologie

  • 2012 - 2014
    • •
  • 4 855 tis. Kč
    • •
  • 4 855 tis. Kč
    • •
  • GA ČR
Project

The Research and Development Information System - Further Development (MI20042007)

We'll develop the R&D Information System (R&D IS) in all of the Recommended Directions of Development of the R&D IS. The take-over of the existing system will not introduce any delays. We'll provide a uniform us...

IN - Informatika

  • 2004 - 2007
    • •
  • 15 239 tis. Kč
    • •
  • 13 780 tis. Kč
    • •
  • ÚřVl ČR
Project

Adenosine deaminase Growth Factors (ME 549)

We perform a collaborative research with the laboratory of supplemental to that funded by the National Science Foundation in a research grant (proposal No. 0091348 "Adenosine Deaminase-related Growth Factors") to Dr. Peter Bryant, Developmen...

EB - Genetika a molekulární biologie

  • 2002 - 2003
    • •
  • 870 tis. Kč
    • •
  • 440 tis. Kč
    • •
  • MŠMT
Project

Drosophila model of adenosine deaminase deficiency (GA204/04/1205)

Adenosine deaminase (ADA) is a metabolic enzyme that catalyzes the irreversible deamination of adenosine and deoxyadenosine to inosine and deoxyinosine. It is present in all organisms including bacteria. Mutations in the ADA gene that result...

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 2 785 tis. Kč
    • •
  • 2 785 tis. Kč
    • •
  • GA ČR
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