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1 089 (0,088s) •

Project

Interactions of Wnt and Ah receptor signaling in regulation of functions of liver cells (GA524/09/1337)

Toxic compounds activating Ah receptor (AhR) present an important group of environmental polutants, which may have deleterious effects on both animal and human health. Analysis of signaling pathways affected by AhR enables to descri...

ED - Fyziologie

  • 2009 - 2011
    • •
  • 3 614 tis. Kč
    • •
  • 3 614 tis. Kč
    • •
  • GA ČR
Project

Interactions of inflammatory mediators and Ah receptor signaling in toxic effects of polycyclic aromatic hydrocarbons (GAP503/11/1227)

to activation of the aryl hydrocarbon receptor (AhR). We expect to obtain a principal novel...

DN - Vliv životního prostředí na zdraví

  • 2011 - 2013
    • •
  • 3 763 tis. Kč
    • •
  • 3 763 tis. Kč
    • •
  • GA ČR
Project

Advanced in vitro models of lung epithelial cells for analysis of airborne pollutants (GA18-00145S)

of the human Ah receptor (AhR). In parallel, the project will focus on evaluation...

Toxicology

  • 2018 - 2023
    • •
  • 9 636 tis. Kč
    • •
  • 8 184 tis. Kč
    • •
  • GA ČR
Project

Linking phenomenology and neurobiology of auditory hallucinations in schizophrenia (NV17-32957A)

Auditory hallucinations (AHs) are the most characteristic symptom and phenomenological point of view. To date, neural mechanisms of AHs are under debate. The most explanation of this typical feature of AHs relates to dialog...

FL - Psychiatrie, sexuologie

  • 2017 - 2020
    • •
  • 12 907 tis. Kč
    • •
  • 12 907 tis. Kč
    • •
  • MZ
Project

Non-conventional environmental Ah receptor ligands and their complex effects in vitro (GA21-00533S)

of polycyclic aromatic contaminants with the aryl hydrocarbon receptor (AhR), in particular with the human AhR; their so far unexplored impact on the nuclear receptors PXR and CAR, key......

Environmental sciences (social aspects to be 5.7)

  • 2021 - 2023
    • •
  • 8 622 tis. Kč
    • •
  • 8 622 tis. Kč
    • •
  • GA ČR
Project

Interactions of genotoxic and non-genotoxic effects of polycyclic aromatic hydrocarbons in regulation of cell proliferation (KJB6004407)

hydrocarbon receptor (AhR), which might play a role in regulation of contact inhibition...

ED - Fyziologie

  • 2004 - 2006
    • •
  • 1 550 tis. Kč
    • •
  • 1 550 tis. Kč
    • •
  • AV ČR
Project

The role of Hippo signaling pathway and organic toxicants in alterations of liver cell function and xenobiotic metabolism (GA13-07711S)

The Ah receptor is a key transcriptional factor activated in response to toxic organic compounds, but also numerous pharmaceuticals or endogenous substances. The AhR plays an important role in liver tissue, controlling not only xeno...

DN - Vliv životního prostředí na zdraví

  • 2013 - 2016
    • •
  • 8 573 tis. Kč
    • •
  • 8 573 tis. Kč
    • •
  • GA ČR
Project

Transverse transport effects in collinear and canted antiferromagnetic hexagonal alloys (GA25-17490S)

The project deals with a theoretical investigation of transverse transport properties, namely anomalous Hall and Nernst effects (AHE, ANE), in solid solutions, but suppressed AHE due to symmetry reasons. Using our approaches, we int...

Condensed matter physics (including formerly solid state physics, supercond.)

  • 2025 - 2027
    • •
  • 5 577 tis. Kč
    • •
  • 5 377 tis. Kč
    • •
  • GA ČR
Project

Towards microscopical understanding of extraordinary magnetoresistance effects (KJB100100802)

The anisotropic magnetoresistance (AMR) and anomalous Hall effect (AHE) have long been known but their detailed microscopic essence remains unclear. GaMnAs is a relatively new material whose bandstructure is simple as compared to metals (Fe,...

BM - Fyzika pevných látek a magnetismus

  • 2008 - 2010
    • •
  • 447 tis. Kč
    • •
  • 447 tis. Kč
    • •
  • AV ČR
Project

Mechanisms of disruption of cell-to-cell communication and regulation of cell proliferation in liver cells (GA524/06/0517)

of Ah receptor ligands on connexins participating in gap junction formation, as well...

ED - Fyziologie

  • 2006 - 2008
    • •
  • 3 007 tis. Kč
    • •
  • 3 007 tis. Kč
    • •
  • GA ČR
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