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280 (0,112s) •

Project

New purine nucleoside analogues for therapeutic applications (OC D13.20)

Synthesis of purine nucleosides, heir acyclic analogues and analogues of nucleotides substituted by C=alkyl, aryl and cycloalkyl substituents as purinoceptor modulators.......

CC - Organická chemie

  • 2001 - 2003
    • •
  • 2 662 tis. Kč
    • •
  • 1 335 tis. Kč
    • •
  • MŠMT
Project

New purine nucleoside analogues for therapeutic applications (1P04OCD13.20)

Synthesis of purine nucleosides, heir acyclic analogues and analogues of nucleotides substituted by C=alkyl, aryl and cycloalkyl substituents as purinoceptor modulators.......

FR - Farmakologie a lékárnická chemie

  • 2004 - 2004
    • •
  • 891 tis. Kč
    • •
  • 400 tis. Kč
    • •
  • MŠMT
Project

Preparation of taxol and its analoques. (PZ-CH/33)

Development a procedure for small-scale production of taxanol its analogues. Preparation of a new taxol analogues....

FR - Farmakologie a lékárnická chemie

  • 1997 - 2001
    • •
  • 15 216 tis. Kč
    • •
  • 7 716 tis. Kč
    • •
  • MH
Project

Testability of analogue and analogue- digital integrated circuits (GA102/95/0875)

JB - Senzory, čidla, měření a regulace

  • 1995 - 1997
    • •
  • 2 524 tis. Kč
    • •
  • 2 524 tis. Kč
    • •
  • GA ČR
Project

Human insulin and its analogues Semisynthetic approache. (PZ-Z2/32)

Biological and physiochemical evaluation of human insulin intermediates. Design and preparation of selected human insulin analogue isolation and physiochemical and biological evaluatio.......

FR - Farmakologie a lékárnická chemie

  • 1997 - 2000
    • •
  • 11 044 tis. Kč
    • •
  • 4 991 tis. Kč
    • •
  • MH
Project

8-Substituted Analogues of Cytokinins - Utilization of their Potential New Quality in Plant Research (KJB6137301)

8-Substituted analogues of natural cytokinins with small substituents in position 8 will be prepared and their structure-activity reationship compared in three bioassays. Analogues with and 8-alkylamino chain will be coupled to prot...

EF - Botanika

  • 2003 - 2005
    • •
  • 3 653 tis. Kč
    • •
  • 978 tis. Kč
    • •
  • AV ČR
Project

Chemical properties of platinum and other metal ion complexes with nucleobases and antiviral nucleotide analogues (OC D8.30)

Synthesis of antiviral compounds with the phosphonate structure containing purine and pyrimidine bases and their aza and deaza analogues, preparation and investigation of their complexes with platinum and other metal ions.......

CC - Organická chemie

  • 1997 - 2001
    • •
  • 2 036 tis. Kč
    • •
  • 1 560 tis. Kč
    • •
  • MŠMT
Project

Brassinolide Analogues with Increased Metabolic Stability (IAA400550609)

synthetic and natural analogues is their low metabolic stability in plant tissues in greenhouse as well as field tests. The project will afford new brassinolide analogues.) of brassinolide analogues.......

CC - Organická chemie

  • 2006 - 2010
    • •
  • 2 676 tis. Kč
    • •
  • 2 676 tis. Kč
    • •
  • AV ČR
Project

Inhibitors of Bacterial RNA Polymerase Based on Nucleotide Analogues (NR9138)

We propose to develop novel inhibitors of bacterial RNA polymerase. Inhibitors will be nucleotide analogues and target its active site.Techniques from molecular biology, organic chemistry, 3D modeling, and high throughput inhibitor testing w...

EE - Mikrobiologie, virologie

  • 2007 - 2009
    • •
  • 9 025 tis. Kč
    • •
  • 8 481 tis. Kč
    • •
  • MZ
Project

Rational synthesis of novel glycosidase inhibitors with antiviral and anticancer activity derived from sugar nitrogen analogues (GA203/96/0308)

Piperidine and pyrrolidine analogues of sugars are important glycosylation inhibitors, exhibiting notable biological effects, e.g. antiviral and anticancer activity analogues: We are especially interested in their C-glycosides and N...

CC - Organická chemie

  • 1996 - 1998
    • •
  • 1 803 tis. Kč
    • •
  • 1 041 tis. Kč
    • •
  • GA ČR
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