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53 (0,101s)

Project

Interaction of Bacillus subtilis rRNA promoters with RNA polymerase Defining elements required for regulation (GP204/05/P510)

decrease dramatically their activity. Recent experiments revealed that in Bacillus subtilis, unlike in Escherichia coli from which we derive most of our knowledge about discriminator, are absent fromB. subtilis. I propose ...

EB - Genetika a molekulární biologie

  • 2005 - 2007
  • 1 174 tis. Kč
  • 1 174 tis. Kč
  • GA ČR
Project

Self-resistance to surfactin in Bacillus subtilis Molecular mechanisms of resistance located in the lipid moiety of the cytoplasmic membrane. (GP13-18051P)

Surfactin produced by Bacillus subtilis is a surfactant and antibiotic permeabilizing the cytoplasmic membrane. Its commercial applications are confined because of limited knowledge of surfactin-membrane interactions and unknown mec...

EE - Mikrobiologie, virologie

  • 2013 - 2015
  • 2 951 tis. Kč
  • 2 951 tis. Kč
  • GA ČR
Project

TRANSCRIPTIONAL CONTROL OF BACTERIAL SPORULATION (GF22-06342K)

in Bacillus subtilis. Consequently, we propose to systematically explore the structure in Bacillus subtilis, focusing on the interplay between RNAP, δ, ω, σ factors and other of pathogens such as Bacillus...

Microbiology

  • 2022 - 2025
  • 10 150 tis. Kč
  • 10 150 tis. Kč
  • GA ČR
Project

Characterization of dynamical regions in RNA polymerase from Bacillus subtilis (GJ18-04197Y)

Gram positive bacterium Bacillus subtilis has been studied so far, showing...

Biochemistry and molecular biology

  • 2018 - 2022
  • 4 670 tis. Kč
  • 4 670 tis. Kč
  • GA ČR
Project

Gene ybxF, a newly identified member of the streptomycin operon of Bacillus subtilis (IAA5052206)

and B. subtilis carries at its 5' end an additional gene, designated ybxF. Its of bacillar ybxF significance is proposed: 1) B. subtilis with removed (knocked-out) abyF......

EB - Genetika a molekulární biologie

  • 2002 - 2005
  • 3 581 tis. Kč
  • 2 327 tis. Kč
  • AV ČR
Project

Structural studies of transcriptional regulators of the DeoR and GntR families involved in catabolic repression in Bacillus subtilis. (ME08016)

been extensively studied in B. subtilis. It requires participation of numerous. subtilis, CggR (central glycolytic genes regulator) and TreR (trehalose operon......

CE - Biochemie

  • 2008 - 2012
  • 1 240 tis. Kč
  • 1 240 tis. Kč
  • MŠMT
Project

Where transcription meets translation (GA23-06295S)

In bacteria, coupling of transcription and translation was described several decades ago. However, we recently discovered an unexpected complex in stationary phase Bacillus subtilis consisting of translation elongation factor Tu (EF...

Microbiology

  • 2023 - 2025
  • 13 183 tis. Kč
  • 13 183 tis. Kč
  • GA ČR
Project

G-domains of elongation factors Tu model proteins for the elucidation of structural elements of thermostability (KJB500520503)

Our experiments showed that the G-domain, the principal functional module of elongation factor Tu, obviously also sets the basic level of thermostability of these proteins. G-domains from mesophilic Bacillus subtilis (growing at 37ř...

EB - Genetika a molekulární biologie

  • 2005 - 2006
  • 547 tis. Kč
  • 547 tis. Kč
  • AV ČR
Project

Artificial Evolution of Thermostable Elongation Factor Tu (GA303/02/0689)

-Tu of Bacillus subtilis and B. stearothermophilus will be expressed in bacteriaThe mechanisms explaining the thermostability of proteins have not been defined yet. In our laboratory, we study the thermostability of elongation facto...

EB - Genetika a molekulární biologie

  • 2002 - 2004
  • 5 624 tis. Kč
  • 2 798 tis. Kč
  • GA ČR
Project

DNA SPECIFICITY-DETERMINING SUBUNITS OF BACTERIAL RNA POLYMERASE WITH FLEXIBLE DOMAINS FUNCTION AND DYNAMICS (GA13-16842S)

the model G+ bacterium Bacillus subtilis, we described the effects of delta...

EB - Genetika a molekulární biologie

  • 2013 - 2017
  • 11 495 tis. Kč
  • 11 495 tis. Kč
  • GA ČR
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