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66 (0,095s) •

Project

The role of tick organs in the transmission of Borrelia afzelii spirochetes (GA22-30920S)

the salivary route of Borrelia transmission had rather a weak effect. Our recent study suggested that Borrelia afzelii, the main agent of Lyme borreliosis in Europe. afzelii transmission. The next goal is to ident...

Microbiology

  • 2022 - 2025
    • •
  • 9 049 tis. Kč
    • •
  • 9 049 tis. Kč
    • •
  • GA ČR
Project

Molecular basis of host-pathogen interactions case study of Borrelia afzelii (8J22AT014)

The main objective of the project is to delineate structural changes of proteins DbpA and DbpB of Borrelia afzelii upon dermatan sulfate binding using European Borrelia using protein mutant in experiments. Obtained data sha...

Biochemistry and molecular biology

  • 2022 - 2023
    • •
  • 62 tis. Kč
    • •
  • 62 tis. Kč
    • •
  • MŠMT
Project

Delineating the role of Borreli afzelii genes required for dissemination within an infected tick during feeding (GA17-21244S)

The Lyme disease spirochete Borrelia afzelii is the most prominent pathogenic techniques adapted for any European Borrelia species has meant no understanding associated with B. afzelii in the tick. It will focus on...

EE - Mikrobiologie, virologie

  • 2017 - 2021
    • •
  • 6 180 tis. Kč
    • •
  • 5 595 tis. Kč
    • •
  • GA ČR
Project

Revision of Borrelia afzelii transmission cycle essential step for Lyme disease interventions (GA17-27393S)

to prevent Lyme disease in humans. One of the promising strategies to break Borrelia cycle for B. afzelii and I. ricinus tick and determination of tick molecules that are essential for Borrelia survival within the host. Ga...

EE - Mikrobiologie, virologie

  • 2017 - 2019
    • •
  • 5 809 tis. Kč
    • •
  • 5 647 tis. Kč
    • •
  • GA ČR
Project

The ability of mosquitoes to transmit Lyme disease spirochetes (NU20-05-00396)

, Borrelia spirochetes are also commonly detected in other blood-feeding arthropods Borrelia, and indicating the possibility that mosquitoes are capable of transmitting the ability of mosquitoes to transmit Borrelia spiroch...

Microbiology

  • 2020 - 2024
    • •
  • 9 812 tis. Kč
    • •
  • 9 812 tis. Kč
    • •
  • MZ
Project

Ecology of borreliae of haematophagous arthropods in Austria and Czech Republic (ME 229)

Lyme borreliosis, caused by Borrelia burgdorferi sensu lato, is an emerging, important infectious disease of man and some other vertebrates. The aim of this project is to compare the occurrence and ecology of borreliae in haematopha...

EE - Mikrobiologie, virologie

  • 1998 - 2000
    • •
  • 394 tis. Kč
    • •
  • 126 tis. Kč
    • •
  • MŠMT
Project

Deciphering the molecular interactions involved in the pathogenesis of European Lyme disease spirochete (7AMB17AT010)

1) Identify host extracellular matrix components, which B. afzelii binds to in order to initiate infection and colonize tissues. 2) Identify outer surface proteins of B. afzelii, which the spirochete uses to bind the extracellular ...

EE - Mikrobiologie, virologie

  • 2017 - 2018
    • •
  • 118 tis. Kč
    • •
  • 118 tis. Kč
    • •
  • MŠMT
Project

Borrelia elimination in ticks unveiling vaccine mechanisms (GA25-16064S)

-mediated inhibitory effect of Borrelia in the system of the European spirochete Borrelia afzelii and the tick Ixodes ricinus using our novel ferritin-based self. There are several vaccines for animals. Vaccines for humans ...

Veterinary science

  • 2025 - 2027
    • •
  • 13 023 tis. Kč
    • •
  • 13 023 tis. Kč
    • •
  • GA ČR
Project

NMR of European borrelia surface proteins (8J20AT024)

investigated. Dbps from other borrelia strains/species. NMR methodology is particularly...

Biochemistry and molecular biology

  • 2020 - 2022
    • •
  • 94 tis. Kč
    • •
  • 94 tis. Kč
    • •
  • MŠMT
Project

Lyme borreliosis spirochetes molecular factors of protein-carbohydrate interactions (GA206/03/1323)

are in a focus of the project with the emphasis on borrelia lectin (LEC), glycosylated surfacestructural unit in borrelia, and glycosyltransferases responsible for posttranslational modification by borrelia spirochtes. Con...

EE - Mikrobiologie, virologie

  • 2003 - 2005
    • •
  • 1 560 tis. Kč
    • •
  • 1 560 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 66