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4 (0,077s)

Project

Cellular and molecular mechanisms of pain modulation at the spinal cord level (GA18-09853S)

with Toll like receptors (TLR4), protease activated receptors (PAR2), CCL2, cytokines...

Neurosciences (including psychophysiology)

  • 2018 - 2020
  • 5 737 tis. Kč
  • 5 405 tis. Kč
  • GA ČR
Project

The role of spinal inhibitory neurons in the development of painful states. (GA20-19136S)

such as CCL2, TNF-alpha and TLR4 receptors. Transgenic mice enabling identification...

Neurosciences (including psychophysiology)

  • 2020 - 2022
  • 6 209 tis. Kč
  • 6 209 tis. Kč
  • GA ČR
Project

The role of cytokines and chemokines in the nociceptive signaling (GPP303/12/P510)

will be on presynaptic mechanism of cytokine TNFα and chemokine CCL2 modulation of TRPV1 hyperalgesia induced by CCL2 intrathecal application was blocked by TRPV1 receptor......

ED - Fyziologie

  • 2012 - 2014
  • 2 619 tis. Kč
  • 2 619 tis. Kč
  • GA ČR
Project

CELLULAR AND MOLECULAR MECHANISMS OF PAIN TRANSMISSION AT SPINAL CORD LEVEL. (GA15-11138S)

Acute pain is an important physiological mechanism that helps to protect organism against damage. Chronic pain is a debilitating disease often characterized by spontaneous pain and by pain induced by innocuous (allodynia) and noxious (hyperalgesia) s...

FH - Neurologie, neurochirurgie, neurovědy

  • 2015 - 2017
  • 4 725 tis. Kč
  • 4 725 tis. Kč
  • GA ČR
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