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14 (0,072s) •

Project

Analysis of the effects of Cd36 (fat) transgene in spontaneously hypertensive rats on clustering of cardiovascular risk factors (GA301/00/1636)

of CD36, a key protein of the cellular transport of fatty acids; 2)CD36 is located ontoSHR background restores normal expression of CD36 and improves cellular defects provided a strong evidence for the involvement of C...

EB - Genetika a molekulární biologie

  • 2000 - 2002
    • •
  • 2 780 tis. Kč
    • •
  • 1 919 tis. Kč
    • •
  • GA ČR
Project

The role of CD36 gene in pathogenesis of Alzheimer´s disease (NV18-04-00455)

The project is focused on the role of CD36 gene in the pathogenesis between CD36 gene and Alzheimer’s disease (AD). CD36 is involved in the removal. CD36 gene will be analyzed for all polymorphisms/mutations by the...

Clinical neurology

  • 2018 - 2021
    • •
  • 11 992 tis. Kč
    • •
  • 11 992 tis. Kč
    • •
  • MZ
Project

Molecular mapping and positional cloning of genes that are responsible for clustering of cardiovascular risk factors (GA305/00/1646)

. However, the role of Cd36 in the pathogenesis of hypertension is unknown and at least oxide synthase (Nos3) and leptin gene (Lep), are linked to Cd36 on chromosome 4. Thus, it is possible that a gene linked to Cd36 such a...

EB - Genetika a molekulární biologie

  • 2000 - 2002
    • •
  • 2 919 tis. Kč
    • •
  • 2 505 tis. Kč
    • •
  • GA ČR
Project

Nutritional and hormonal regulation of synthesis and transport fatty acids in insulin resistance (NR7888)

of Cd36 fatty acid transporter and transgenic SHR rats with expression of Cd36 or aP2...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2006
    • •
  • 5 556 tis. Kč
    • •
  • 5 049 tis. Kč
    • •
  • MZ
Project

Modulation of Fatty Acid Reesterification in Adipose Tissue by Lipid Mediators (LH14040)

portion of fatty acids is reesterified, how are fatty acid transporters (e.g. CD36 and adipose tissue with respect to fatty acid transporter CD36 and composition of dietary specialized methods of mass spectrometry, cells and mice w...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2014 - 2016
    • •
  • 1 910 tis. Kč
    • •
  • 1 910 tis. Kč
    • •
  • MŠMT
Project

Metabolic flux analysis of carbohydrates and lipids in adipose tissue (LTAUSA17173)

. Multifunctional protein CD36 is also involved in fatty acid utilization via the interaction...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2017 - 2019
    • •
  • 2 284 tis. Kč
    • •
  • 2 284 tis. Kč
    • •
  • MŠMT
Project

New metabolic pathways of lipid trafficking (LUAUS24040)

of fatty acids during transcytosis in relation to the presence of the CD36 transporter. Signalling through lipokines 3.1 Define the signaling potential of FAHFA through the CD36......

Biochemistry and molecular biology

  • 2024 - 2027
    • •
  • 10 122 tis. Kč
    • •
  • 10 122 tis. Kč
    • •
  • MŠMT
Project

Mixed myelodysplastic and myeloproliferative syndromes (MDS-MPS) (IZ4119)

The project propsal has 4 targets:1.to extend the number up to now examined MDS-MPS patients and to divide them in homogenous groups.2.to elaborate the dif.dg criteria.3.to find optimal therapy. 4.to study the CD36 decreased expression,apopt...

FD - Onkologie a hematologie

  • 1997 - 1999
    • •
  • 1 709 tis. Kč
    • •
  • 1 429 tis. Kč
    • •
  • MZ
Project

Pathogenesis of cardiovascular risk factors cluster analyzed by transgenesis with Srebp1c transcription factor (NB6468)

Sterol regulatory element binding protein 1c (Srebplc) could be a central mediator of the genomic actions of insulin on carbohydrate and lipid metabolism and might thus contribute to the pathogenesis of type 2 diabetes or obesity. To test this hypoth...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 5 033 tis. Kč
    • •
  • 3 454 tis. Kč
    • •
  • MZ
Project

Toxicological characteristics of the impact of fodder crops planted in antropogenically contaminated soil on oxidative stress and element level (GA523/06/0439)

of hypertension and human metabolic syndrome and diabetes 2. Among several genes, CD36...

GH - Výživa hospodářských zvířat

  • 2006 - 2008
    • •
  • 3 070 tis. Kč
    • •
  • 3 070 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 14