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5 (0,053s)

Project

Extramedullary multiple myeloma molecular pathogenesis and novel therapeutical targets (NU23-03-00374)

CD38 and SREBF1 pathways as potentially crucial for acquisition of EMD phenotype of CD38 and SREBF1 pathways using sophisticated in vitro and in vivo approaches. Our......

Oncology

  • 2023 - 2026
  • 13 741 tis. Kč
  • 13 741 tis. Kč
  • MZ
Project

Predictive immunological markers in patients with hepatitis C viral infection (NT14072)

The following markers will be examined in the blood of adult patients with chronic hepatitis C (HC), genotype 1b in Prague and Hradec Králove: 1) Expression of activation markers CD38 a HLA-DR on the cytotoxic T lymphocytes (CTLs) presents t...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2013 - 2015
  • 7 567 tis. Kč
  • 7 567 tis. Kč
  • MZ
Project

Effect of long-term asymptomatic Toxoplasma gondii infection on the immune and clinical state of HIV-positive patients (NT11429)

The objective of the project is to find out whether and to what extent toxoplasmosis modulates the immune response in HIV-positive subjects and through its long-term effect contributes to any shortening of their survival.The applicants plan to compar...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2010 - 2014
  • 4 338 tis. Kč
  • 4 338 tis. Kč
  • MZ
Project

Complex assessment of microenvironment and its impact on clinical course of chronic lymphocytic leukemia. (NT13412)

doubling time, expresssion of CD38 a ZAP-70, IgVH mutation status, cytogenetic...

FD - Onkologie a hematologie

  • 2012 - 2015
  • 3 024 tis. Kč
  • 3 024 tis. Kč
  • MZ
Project

Significance of TACI mutations and lymphocyte subpopulations in pathogenesis of selective IgA deficiency (NS10398)

,CD127 antigens. CD21-CD38- B-cells will also be studied by immunophenotype analysis...

EC - Imunologie

  • 2009 - 2011
  • 3 035 tis. Kč
  • 3 035 tis. Kč
  • MZ
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