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1 532 (0,071s) •

Project

Circulating microvesicles (microparticles and exosomes) for diagnosis of gynecological malignancies (NT12248)

of gynecological cancer. The aim of the project is to identify molecular characteristics of plasma circulating ovarian cancer and endometrial cancer specific microvesicles. To identify cancer specific biomarkers w...

FK - Gynekologie a porodnictví

  • 2011 - 2015
    • •
  • 6 321 tis. Kč
    • •
  • 6 321 tis. Kč
    • •
  • MZ
Project

Role of exosomes in information transfer between cancer-associated fibroblasts and cancer cell, with emphasis on malignant melanoma (GA19-05048S)

Cancer incidence is increasing worldwide, but mainly in developed countries research and data of other authors demonstrated a remarkable role of cancer microenvironment on growth and spreading of malignant tumors with important role...

Oncology

  • 2019 - 2021
    • •
  • 12 364 tis. Kč
    • •
  • 11 878 tis. Kč
    • •
  • GA ČR
Project

Induction of pyroptosis in cancer cells - potential therapeutic method for pancreatic cancer (FW01010527)

cancer. Developed agent will be based on induction of proinflammatory cell death - pyroptosis - in pancreatic cancer cells. Adeno-associated viral vectors (AAV innovative approach to biological treament of cancer. The appr...

Biochemistry and molecular biology

  • 2020 - 2024
    • •
  • 11 252 tis. Kč
    • •
  • 6 072 tis. Kč
    • •
  • TA ČR
Project

BRCA1 alternative splicing variants and their prognostic and predictive role in breast cancer (NT12280)

cancer. cDNA will be synthesized from RNA isolated from mammary tissue samples receivedfrom breast cancer patients and from women without breast cancer and from with breast cancer and controls will be statisticall...

FD - Onkologie a hematologie

  • 2011 - 2014
    • •
  • 5 159 tis. Kč
    • •
  • 5 159 tis. Kč
    • •
  • MZ
Project

Characterization of metalloproteins important in cancer their interactions with DNA (OC D21.002)

Characterization of metalloproteins important in cancer their interactions with DNA...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2002 - 2005
    • •
  • 3 290 tis. Kč
    • •
  • 1 265 tis. Kč
    • •
  • MŠMT
Project

ProstaPilot. Prostate cancer screening with abbreviated MRI protocol (NU22-09-00539)

Prostate cancer is one of the most common cancers in men, comparable in incidence and mortality to breast cancer in women. Not all cancers have the potential to cause harm to health; these clinically non-significan...

Oncology

  • 2022 - 2025
    • •
  • 6 455 tis. Kč
    • •
  • 6 455 tis. Kč
    • •
  • MZ
Project

Plasticity of prostate cancer cells and chemotherapy resistance (7AMB16AT022)

1. Correlation of EMT fingerprint with chemotherapy resistance in prostate cancer 2. Analysis of novel molecular factors involved in EMT and chemotherapy resistance 3. Analysis of the role of miR-34a in EMT and chemotherapy resistance in pro...

FD - Onkologie a hematologie

  • 2016 - 2017
    • •
  • 68 tis. Kč
    • •
  • 68 tis. Kč
    • •
  • MŠMT
Project

Germline mutations of PML gene in patients with cancer (NR9092)

Mutational analysis of PML gene will be performed in patients with breast and colon cancer with suspect hereditary predisposition to cancer. Cyclin D1 and ZNF217 gene amplification analysis will be performed in breast cancer

FD - Onkologie a hematologie

  • 2006 - 2008
    • •
  • 2 645 tis. Kč
    • •
  • 2 244 tis. Kč
    • •
  • MZ
Project

The significance of D2 lymphadenectomy in gastric cancer surgery (NS10550)

Lymph nodes involvement is one of main indipendent prognostic factors in gastric cancer. Clinical and prognostic impact of minimal involvement of lymph nodes (micrometastasis and isolated cancer cells) is still unclear. The aim of t...

FJ - Chirurgie včetně transplantologie

  • 2009 - 2011
    • •
  • 4 057 tis. Kč
    • •
  • 4 057 tis. Kč
    • •
  • MZ
Project

Genetics and immunity in early stages of colorectal adenocarcinoma inflammatory environment inconventional vs germ-free animal models, and in human samples (IAA500200917)

in cancer and inflammation relationships. We will study arise of cancer in DSS-AOM induced colorectal cancers in the rat. We will look for genetic/immunologic independent markers of cancer evolution. Data will be ...

EC - Imunologie

  • 2009 - 2013
    • •
  • 6 611 tis. Kč
    • •
  • 6 611 tis. Kč
    • •
  • AV ČR
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