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33 (0,069s) •

Project

Role of aspartic proteinases in nutrient acquisition and starvation of pathogenic yeasts Candida albicans and Candida parapsilosis (GA310/09/1945)

Opportunistic pathogens of the genus Candida produce secreted aspartic proteins as a source of nutrients. While the secreted proteinases of pathogenic Candida aspartic proteinases. They are predicted to play a role in adaptation of ...

EE - Mikrobiologie, virologie

  • 2009 - 2011
    • •
  • 1 677 tis. Kč
    • •
  • 1 677 tis. Kč
    • •
  • GA ČR
Project

Study of structures of carbonic anhydrases from pathogenic Candida spp. as a tool for design of potential antimycotics (GA17-08343S)

Candida albicans and Candida parapsilosis are opportunistic human pathogens and represent a serious threat to immunocompromised patients. Pathogenic Candida species, Candida possesses carbonic anhydrase (C...

EE - Mikrobiologie, virologie

  • 2017 - 2021
    • •
  • 7 187 tis. Kč
    • •
  • 5 444 tis. Kč
    • •
  • GA ČR
Project

Functional study of the Na+, K+/H+antiporter Cnh1p in the pathogenic yeast Candida albicans (KJB5011307)

Intracellular pH and K+ content belong among factors controlling morphology of a diploid fungus Candida albicans. The C. albicans CNH1 gene encodes a Na+/H+-antiporter. albicans strains lacking one or both CNH1 all...

EB - Genetika a molekulární biologie

  • 2003 - 2004
    • •
  • 597 tis. Kč
    • •
  • 329 tis. Kč
    • •
  • AV ČR
Project

Secreted Aspartic Proteinases of Candida spp. targets for drug developing (GA303/98/1612)

Pathogenesis of Candida sp. is strongly dependent on the production of aspartic a number of tissue proteins and thus facilitate deep invasion of Candida spp., causing seriuos infections, particularly in immunocompromised patients. I...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1998 - 2000
    • •
  • 2 338 tis. Kč
    • •
  • 2 000 tis. Kč
    • •
  • GA ČR
Project

Transporters of the pathogenic Candida yeast species as a target for the development of new antifungal drugs. (GA16-03398S)

molecular aspects of Candida albicans and Candida glabrata virulence and pathogenicityThe project will target the most common human fungal pathogens, the opportunistic Candida yeast species, which are able to succ...

EE - Mikrobiologie, virologie

  • 2016 - 2018
    • •
  • 4 888 tis. Kč
    • •
  • 4 713 tis. Kč
    • •
  • GA ČR
Project

Study of the role of different isoenzymes of aspartic proteases in the virulence of Candida spp. (GA303/04/0432)

Candida infections cause diseases ranging from superficial disorders Candida spp. provide a broad range of virulence factors. One major group of Candida spp. Although protease production has been observed during experimenta...

CE - Biochemie

  • 2004 - 2006
    • •
  • 1 215 tis. Kč
    • •
  • 1 215 tis. Kč
    • •
  • GA ČR
Project

Mechanism of activation of the proteinases secreted by the pathogenic yeast Candida parapsilosis (GA203/05/0038)

Candida parapsilosis is an opportunistic pathogen. Its virulence factors have not been studied so thoroughly as those of C. albicans. Secreted aspartic proteinases (Sap) are believed to play a role in virulence of C. parapsilosis. 3...

CE - Biochemie

  • 2005 - 2007
    • •
  • 1 407 tis. Kč
    • •
  • 1 407 tis. Kč
    • •
  • GA ČR
Project

CANDI-Biotechnologicla production of plant sources of health-promoting substances for the human digestive tract (LTE218006)

The aim of the present project is to develop a prototype of a healthy drink produced from natural raw materials that will not contain added sugar and will have a defined composition, including specific plant substances produced under controlled condi...

Agricultural biotechnology and food biotechnology

  • 2018 - 2021
    • •
  • 13 336 tis. Kč
    • •
  • 6 668 tis. Kč
    • •
  • MŠMT
Project

Comparison of a Recombinant hsp90 Protein Vaccine and DNA Vaccine Protectivity in Mouse Vaginal and Systemic Candidiasis Model (NI7538)

Candida albicans hsp90 protein is considered as an immunodominant potentially protective antigen suitable to induce specific T cells and specific antibodies protective against mucosal and disseminated candidiasis. Induction of autoi...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2003 - 2005
    • •
  • 2 141 tis. Kč
    • •
  • 2 101 tis. Kč
    • •
  • MZ
Project

Increasing participation of the Czech scientists in activities of the international scientific societies - The RNA Society, SGM and FEMS (LA10023)

. albicans and hepatitis C virus....

EE - Mikrobiologie, virologie

  • 2010 - 2012
    • •
  • 2 808 tis. Kč
    • •
  • 2 808 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 33