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3 696 (0,106s) •

Project

Carcinogenic risk of chemical substances in metallurgy (IZ1696)

9F - 9

  • 1993 - 1996
    • •
  • 173 tis. Kč
    • •
  • 346 tis. Kč
    • •
  • MZ
Project

Development of modern electrochemical methods for monitoring of nitrogen-containing chemical carcinogens (GA203/03/0182)

is to developelectrochemical methods for the determination of nitrogen-containing chemical carcinogens from concentrations of the tested carcinogens and......

CB - Analytická chemie, separace

  • 2003 - 2005
    • •
  • 1 330 tis. Kč
    • •
  • 730 tis. Kč
    • •
  • GA ČR
Project

Role of specific cytochrome P 450 forms in selected derivatives of benzen and acrylic acid metabolic activation individual disposition to chemical carcinogenes (IZ260)

FM - Hygiena

  • 1991 - 1994
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MZ
Project

Silenced Cells Speak Volumes Dysregulated Gap Junctional Intercellular Communication as a Key Process for Identifying Non-Genotoxic Carcinogens (GA24-12116S)

The discovery of the link between human chemical exposures and cancer dates back over 250 years. With the increasing use of chemicals in consumer products risks to protect public health. Non-genotoxic carcinogens (NGTxC), w...

Cell biology

  • 2024 - 2026
    • •
  • 7 845 tis. Kč
    • •
  • 7 845 tis. Kč
    • •
  • GA ČR
Project

Molecular study of carcinogenicity of o-nitroanosole and o-anisidine, cancerogens with unknown mechanism (GA203/99/1003)

The proposed project is aimed at elucidation of mechanism of carcinogenicity of two important industrial pollutants, o-nitroanisole and o-anisidine as models, representing the group of carcinogens with yet unexplained mechanism. The...

CE - Biochemie

  • 1999 - 2001
    • •
  • 1 090 tis. Kč
    • •
  • 1 090 tis. Kč
    • •
  • GA ČR
Project

Genotoxic and non-genotoxic mechanisms involved in carcinogenicity of complex mixtures of air pollutants toxicogenomic approach (GAP503/11/0142)

Human environmental exposure to chemicals mostly involves complex mixtures containing genotoxic as well as non-genotoxic carcinogens. Multistage process of chemical carcinogenesis relates both genotoxic as well as non-genot...

DN - Vliv životního prostředí na zdraví

  • 2011 - 2015
    • •
  • 11 588 tis. Kč
    • •
  • 11 588 tis. Kč
    • •
  • GA ČR
Project

Mechanisms of genotoxic effects of chemical carcinogen 1,3butadien adaptive response and individual susceptibility (GA310/01/0802)

1,3-Butadiene (BD), an important industrial and environmental xenobiotic, was shown to be genotoxic, but mechanisms of BD genotoxicity are not clear. The aim of the project would be an investigation of relationships between various biomarkers, DNA re...

FM - Hygiena

  • 2001 - 2003
    • •
  • 9 744 tis. Kč
    • •
  • 4 767 tis. Kč
    • •
  • GA ČR
Project

The use of electrochemical methods for the determination of carcinogenic nitrated polycyclic aromatic hydrocarbons and monitoring their transformations in vitro (GA203/98/1187)

to the pollutants. Moreover, new methods of destruction of these chemicals carcinogens suitable...

CB - Analytická chemie, separace

  • 1998 - 2000
    • •
  • 750 tis. Kč
    • •
  • 690 tis. Kč
    • •
  • GA ČR
Project

Study on structure-function relationship of cytochromes P450 - key enzymes involved in drug metabolism and carcinogen activation (GA303/06/0928)

. drugs, and carcinogen activation. The aim of the project is a validation and carcinogen risk assessment. To accomplish this task a combination of research techniques will be used. Research strategy of the enzyme structure is based...

CE - Biochemie

  • 2006 - 2008
    • •
  • 3 971 tis. Kč
    • •
  • 3 971 tis. Kč
    • •
  • GA ČR
Project

The mechanisms of carcinogenic processes in normal and transformed airway cellular models exposed to airborne aromatic toxicants (GA19-25365S)

of many in vivo and in vitro studies, the mechanisms of toxicity and carcinogenicity“ toxicity, including promotion/progression of lung cancer. Chemically-induced......

Toxicology

  • 2019 - 2023
    • •
  • 8 012 tis. Kč
    • •
  • 8 012 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 3 696