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198 (0,139s) •

Project

Molecular nature of DNA replication-coupled chromatin modulation (GA304/06/1691)

dependent modulation of early replicating chromatin domains manifested in situ by antibody-detected epiC positivity. By means of native chromatin immunoprecipitation and amino acid sequence analysis we want to identify chromati...

EA - Morfologické obory a cytologie

  • 2006 - 2008
    • •
  • 4 731 tis. Kč
    • •
  • 4 731 tis. Kč
    • •
  • GA ČR
Project

Organization of human nuclear chromatin (GA204/09/0973)

In this project, we want to deepen the knowledge of interphase chromatin organization. Human aneuploid carcinoma cell line and human diploid fibroblasts will serve in replicated human chromatin and its role in the organization of re...

EA - Morfologické obory a cytologie

  • 2009 - 2011
    • •
  • 4 237 tis. Kč
    • •
  • 4 237 tis. Kč
    • •
  • GA ČR
Project

The SMC5/6 complex in nucleome organization (LTC20033)

a) Characterization of activities of the SMC5/6 complexes b) Determination of the chromatin localization and dynamics of SMC5/6 c) Identification of chromatin loops dependent on SMC5/6 activities d) Development of visual models o...

Biochemistry and molecular biology

  • 2020 - 2023
    • •
  • 7 289 tis. Kč
    • •
  • 7 289 tis. Kč
    • •
  • MŠMT
Project

Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus (ME09101)

Identification of principles of collaborative action of actin-related (Arp6) and mypson (NM1) proteins in functional organization of the cell nucleus and chromatin. The project aims to asses especially their contribution to the organization ...

EB - Genetika a molekulární biologie

  • 2009 - 2010
    • •
  • 1 336 tis. Kč
    • •
  • 1 336 tis. Kč
    • •
  • MŠMT
Project

Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus (LH12143)

Identification of principles of collaborative action of actin-related Arp6) and myosin (NM1) proteins in functional organization of the cell nucleus and chromatin, to the dynamics of chromatin movements, and to the formation of tran...

EB - Genetika a molekulární biologie

  • 2012 - 2014
    • •
  • 3 635 tis. Kč
    • •
  • 3 635 tis. Kč
    • •
  • MŠMT
Project

High throughput analysis of chromatin structure for development of novel diagnostic and therapeutic approaches in cancer. (2B06077)

DNA in nucleus is wrapped into nucleo-protein structure known as chromatin. Any transaction on DNA requires interactions of chromatin with transcription, replication-associated transcription and chromatin-modifying factors ...

EB - Genetika a molekulární biologie

  • 2006 - 2011
    • •
  • 53 217 tis. Kč
    • •
  • 47 631 tis. Kč
    • •
  • MŠMT
Project

Replication and chromatin organization in human cells (GA304/05/0374)

In this project, we want to show the high-resolution view of chromatin cells and human diploid fibroblasts. Recently, we showed that chromatin of HeLa replication results in the structural chromatin changes in the vicinity ...

EA - Morfologické obory a cytologie

  • 2005 - 2007
    • •
  • 4 362 tis. Kč
    • •
  • 4 362 tis. Kč
    • •
  • GA ČR
Project

Dynamic structure and function of the cell nucleus after irradiation (1P05OC084)

changes of structure of chromatin caused by low doses of ionizating radiation, changes of nucleus topology of chromatine...

BO - Biofyzika

  • 2005 - 2007
    • •
  • 2 522 tis. Kč
    • •
  • 1 043 tis. Kč
    • •
  • MŠMT
Project

Chromatin dynamics during DNA repair (GAP302/10/1022)

to this knowledgeby the elucidation of the processes changing the chromatin structure in the DSB vicinity. Chromatin changes represent the fundamental response of the cell to DSB andrepair. It should be found how the chromatin<...

EA - Morfologické obory a cytologie

  • 2010 - 2014
    • •
  • 6 265 tis. Kč
    • •
  • 6 265 tis. Kč
    • •
  • GA ČR
Project

Analysis of replication and DNA damage response in plants deficient in accurate chromatin assembly (GP13-11563P)

Correct chromatin assembly is in each cell regulated by chromatin remodelling complexes and histone chaperones. One of the most important chromatin remodellers is the Chromatin Assembly Factor 1 (CAF1). It is a wel...

EB - Genetika a molekulární biologie

  • 2013 - 2015
    • •
  • 2 603 tis. Kč
    • •
  • 2 603 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 198