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23 (0,143s)

Project

Conditions of food delivery by courier services with regard to the growth of sporogenic bacteria (QK23020061)

1) To determine the conditions (temperature and time) of growth of selected sporogenic bacteria (Bacillus cereus and Clostridium perfringens) in different types of hot meals after their artificial contamination. 2) Check selected i...

Food and beverages

  • 2023 - 2025
  • 7 865 tis. Kč
  • 7 865 tis. Kč
  • MZe
Project

Risk of the occurrence of Cryptosporidium spp. oocysts in drinking water (IBS6022006)

of autbreaks. The cultivation of all samples for Clostridium perfringens presence...

DJ - Znečištění a kontrola vody

  • 2000 - 2004
  • 6 670 tis. Kč
  • 2 522 tis. Kč
  • AV ČR
Project

Development of unique vaccines against serious diseases of animals (TH01010837)

1. Development of unique polyvalent vaccines for immunization sows and cows before farrowing against enteric diseases of their offspring. A wide range of antigens contained in the vaccine permits to induce an effective protection through one or two a...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2015 - 2016
  • 23 258 tis. Kč
  • 12 450 tis. Kč
  • TA ČR
Project

The potential of xanthohumol and beta-bitter acids in the therapy of nosocomial infections (NV17-31765A)

, namely Clostridium perfringens and C. difficile. Some of the other characteristics...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2017 - 2020
  • 11 693 tis. Kč
  • 11 164 tis. Kč
  • MZ
Project

Incidence and typing of pathogenic strains of Clostridium difficile in the Czech Republic (KJB500200901)

Anaerobic, spore-forming bacterium Clostridium difficile is an important nosocomial pathogen and the most frequently diagnosed cause of hospital-acquired diarrhoea. Toxigenic strains usually produce enterotoxin A and cytotoxin B, which (...

EE - Mikrobiologie, virologie

  • 2009 - 2011
  • 1 073 tis. Kč
  • 1 073 tis. Kč
  • AV ČR
Project

In vitro activity of new hybrid lincosamide antibiotics against clinical Clostridioides (Clostridium) difficile (NU21-05-00278)

Clostridioides (Clostridium) difficile is a major pathogen of the hospital-acquired diarrhoea with an increasing incidence also outside healthcare facilities, in the community. The number of drugs for C. difficile infection treatment is limi...

Microbiology

  • 2021 - 2024
  • 9 816 tis. Kč
  • 9 816 tis. Kč
  • MZ
Project

Biotechnologically customised collagenase for preparation of advanced therapy medicinal products (FV20139)

The aim of the project is to develop advanced production technologies for efficient purification of individual proteases that represent the active component of traditional collagenase brands. Crude collagenase is produced by fermentation of Clost...

EI - Biotechnologie a bionika

  • 2017 - 2021
  • 31 372 tis. Kč
  • 18 784 tis. Kč
  • MPO
Project

Isolation and characterization of bilirubin reductase gene from bacteria of Clostridium genus and its potential therapeutic use (GA310/02/1436)

of Clostridium sp. capable of bilirubin reduction. The aim of the project...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2002 - 2004
  • 4 926 tis. Kč
  • 3 678 tis. Kč
  • GA ČR
Project

Chitinolytic enzymes from Clostridium paraputrificum inhabiting the human gastrointestinal tract; structure and biomedical implications. (GA310/09/1407)

The bacterium Clostridium paraputrificum J4 inhabiting the gastrointestinal tract of humans is involved in food digestion by secretion of chitinolytic enzymes which are not expressed by human cells. These enzymes defend humans from food-born...

EE - Mikrobiologie, virologie

  • 2009 - 2013
  • 8 074 tis. Kč
  • 8 074 tis. Kč
  • GA ČR
Project

Clostridium difficile genotyping and phenotyping of clinically significant isolates - a survey of the epidemiological situation in the Czech Republic (NT14209)

Toxigenic Cd is currently a significant nosocomial pathogen. Globally, the incidence and severity of infections caused by these bacteria has been growing in recent years, while the situation has worsened in some regions of the CR as well. However, co...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2013 - 2015
  • 3 038 tis. Kč
  • 2 860 tis. Kč
  • MZ
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