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302 (0,309s) •

Project

Immunoprophylaxis of Escherichia coli infections of piglets after weaning (EP9181)

on the study of colonization possibilities of the intestinal tract of piglets with E.coli colonization with E.coli strains, equiped with colonization factors K88, is the most effective. Nonpathogenic strains E.coli with

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 1999 - 2002
    • •
  • 1 740 tis. Kč
    • •
  • 1 740 tis. Kč
    • •
  • MZe
Project

Wnt ligands and Wnt-secreting cells for intestinal homeostasis, regeneration and colon cancer a complex world beyond the cancer-activating mutation (GA18-21466S)

Targeting Wnt signaling represents a promising therapy against colon cancer. Although the role of Wnt-activating mutation for initiation and progression of colon the role of Wnt ligands in progression of colon cancer. In Re...

Developmental biology

  • 2018 - 2022
    • •
  • 8 406 tis. Kč
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  • 7 632 tis. Kč
    • •
  • GA ČR
Project

From past to present fossil vs. recent marine shelled organisms as a substrate for colonization and bioerosion (GA18-05935S)

Shells of marine organisms are specific hard substrates colonized since colonization zones: the outer surface, the inner space and the shell matter with its of variegated microniches colonized by specific communities; 2) Sp...

Geology

  • 2018 - 2023
    • •
  • 9 036 tis. Kč
    • •
  • 8 548 tis. Kč
    • •
  • GA ČR
Project

Increased secretory activity of murine colon in the early phase of dextran sodium sulfate-induced inflammation (GPP303/12/P320)

The project is focused on ion transport in murine colon in the early phase secretory activity of colon after 3 days of dextran sodium sulfate (DSS) administration. In contrast to related papers, functional division of colon...

ED - Fyziologie

  • 2012 - 2016
    • •
  • 1 517 tis. Kč
    • •
  • 1 517 tis. Kč
    • •
  • GA ČR
Project

Prevention of allergies by colonization of the intestine with a nonpathogenic E.coli strain (vaccine COLINFANT) administered orally at birth to infants of allergic mothers. Long-term study (NI7525)

Preventing development of allergy by oral colonization of intestine of infants of allergic mothers with strain E.coli (vaccine Colinfant) after birth in a double-blind study. Follow development of immune reactions in colonized infan...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2003 - 2005
    • •
  • 6 975 tis. Kč
    • •
  • 6 681 tis. Kč
    • •
  • MZ
Project

Antiproliferative effects of bilirubin, heme metabolites, and heme oxygenase expression on colon and pancreatic cancer. (ME 849)

detailed study on the role of bilirubin metabolism in phatogenesis of colon and pancreatic cancer, basic research, database research...

FD - Onkologie a hematologie

  • 2006 - 2009
    • •
  • 2 890 tis. Kč
    • •
  • 2 770 tis. Kč
    • •
  • MŠMT
Project

Glycosphingolipids and their metabolic pathways as potential colon cancer biomarkers (NU21-03-00421)

Colon cancer represents one of the most common cancer types in the Czech mortality remains high. Identification of suitable prognostic colon cancer markers may. Our preliminary results suggest that in colon tumors, there oc...

Oncology

  • 2021 - 2025
    • •
  • 14 495 tis. Kč
    • •
  • 14 448 tis. Kč
    • •
  • MZ
Project

Function of metalloproteinases in colon epithelium and during development of experimental colitis and colon cancer. (GAP302/11/2048)

of the colon and in macrophages. Our previous studies showed that MMP19-deficient mice of MMPs we will study their impact on chronic colitis and their involvement in colon carcinoma. Todissect specific roles of the proteinases in <...

EC - Imunologie

  • 2011 - 2014
    • •
  • 7 358 tis. Kč
    • •
  • 7 358 tis. Kč
    • •
  • GA ČR
Project

The role of c-Myb and Cox-2 proteins in colon carcinogenesis (GA301/09/1115)

Colon carcinomas are frequent malignant tumors in the Czech Republic. c-Myb is significantly involved in control of differentiation, proliferartion and apoptosis of colon cells. This transcription factor can regulate phenotype of a ...

FD - Onkologie a hematologie

  • 2009 - 2012
    • •
  • 3 915 tis. Kč
    • •
  • 3 915 tis. Kč
    • •
  • GA ČR
Project

The role of extracellular matrix-mediated cell adhesion in maintenance of colonic tissue homeostasis and in colon carcinogenesis (GA305/09/1526)

Right physiological functioning of the intestinal tissue is important for general health of mammalian organism. In colon crypt the epithelial cells migrate epithelial cell anchorage mediated by ECM in maintenance of colonic tissue h...

ED - Fyziologie

  • 2009 - 2011
    • •
  • 2 718 tis. Kč
    • •
  • 2 718 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 302