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1 569 (0,088s)

Project

Study of genetic predispositions to colorectal cancer (NR8294)

We will study germline mutations in the MLH1, MSH2, MSH6, and MYH genes as a possible molecular cause of the disease in patients with colorectal cancer (CRC of the project will add to the understanding of molecular basis of colo...

EB - Genetika a molekulární biologie

  • 2005 - 2007
  • 3 100 tis. Kč
  • 3 047 tis. Kč
  • MZ
Project

Identification of determinants associated with metastatic colorectal cancer in relation to Anterior gradient 2 (GA19-02014S)

Colorectal cancer is one of the most common cancers as well as one of the leading causes of cancer-related deaths in the western world. During epithelial with colorectal cancer. The main objective...

Cell biology

  • 2019 - 2021
  • 6 255 tis. Kč
  • 5 946 tis. Kč
  • GA ČR
Project

Molecular-biological and histopathological characteristics of tumor infiltrating lymphocytes as instrument of prediction of risk of early colorectal cancer recurrence (NT12025)

Overal survival of patients with radicaly operated colorectal cancer biological,histopathological and immunohistochemical profile of early colorectal cancer on micrometastatical dissemination of cancer. Th...

FJ - Chirurgie včetně transplantologie

  • 2011 - 2014
  • 5 261 tis. Kč
  • 5 261 tis. Kč
  • MZ
Project

The efficiency of colonic capsule endoscopy in detection of colorectal polyps and cancers comparing to colonoscopy multicenter, prospective crosses over study (NT11524)

of colorectal polyps and cancers in individuals with average risk of colorectal cancer be useful in colorectal cancer screening in population with high prevalenceof and cancers, the sens...

FE - Ostatní obory vnitřního lékařství

  • 2010 - 2014
  • 7 746 tis. Kč
  • 7 276 tis. Kč
  • MZ
Project

Identification and functional studies of microRNAs with predictive and prognostic significance in patients with colorectal cancer (NS9814)

The main goal of our project is contribution to the knowledge of molecular biology of colorectal carcinoma by analysis of microRNA expression profiles of the primary colorectal tumors and utilization of our results for improvement o...

FD - Onkologie a hematologie

  • 2008 - 2011
  • 5 834 tis. Kč
  • 5 795 tis. Kč
  • MZ
Project

Sreening evaluation and malignant potential of colorectal cancer (CR-CA). (IZ4217)

The project includes an evaluation program of colorectal cancer screening in asymptomatic subjects and a study of the malignant potential of this neoplasm.......

FD - Onkologie a hematologie

  • 1997 - 1999
  • 2 376 tis. Kč
  • 2 212 tis. Kč
  • MZ
Project

Targeted colorectal cancer screening in type 2 diabetes patients and high cardiovascular risk patients multicentric prospective study (NT13673)

of colorectal neoplasia (colorectal cancer, advanced adenoma) alongside. In years 2012 by colonoscopy. Only persons, who fulfill the criteria for colorectal cancer screening (asymptomatic, negative person...

FE - Ostatní obory vnitřního lékařství

  • 2012 - 2015
  • 14 478 tis. Kč
  • 13 237 tis. Kč
  • MZ
Project

Autoimunne thyroid diseases in women with breast and colorectal cancer (NR8130)

The aim of the project is to compare the prevalence of thyroid autoimmune diseases in women with breast cancer and colorectal cancer. 150 women with breast cancer and 150 women with colorectal cancer

FD - Onkologie a hematologie

  • 2004 - 2006
  • 995 tis. Kč
  • 992 tis. Kč
  • MZ
Project

Analysis of EGFR signalling and microRNA expression profiles in prediction of response to anti-EGFR therapy in colorectal cancer patients with wild-type KRAS (NT13860)

In the proposed project we are aiming idetification of the new molecular markers (effector molecules of EGFR signalling, microRNAs) enabling response prediction to anti-EGFR therapy in patients with metastastic colorectal cancer car...

FD - Onkologie a hematologie

  • 2012 - 2015
  • 6 455 tis. Kč
  • 6 455 tis. Kč
  • MZ
Project

MicroRNAs significance in chemoprotective effects of phytochemicals contained in Brassica vegetables and association of their binding sites polymorphisms with risk of colorectal cancer (NS10352)

to consumption of Brassica vegetables and prevention of colorectal cancer in the future.Our study is based on the new microRNA-based methodical approach to identification of new genetic factors with potential to attenuate or enhanc...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2009 - 2011
  • 4 819 tis. Kč
  • 4 392 tis. Kč
  • MZ
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