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39 (0,061s) •

Project

Application of capillary electrophoresis in dried blood spots analysis (GA18-13135S)

blood spots (DBS) have been increasingly used in clinical applications, too. In this project, DBS will be analysed by capillary electrophoresis (CE), which has only scarcely been involved in recent developments in the field of ...

Analytical chemistry

  • 2018 - 2021
    • •
  • 5 888 tis. Kč
    • •
  • 5 324 tis. Kč
    • •
  • GA ČR
Project

STN-DBS outcomes in Parkinson´s disease the influence of vascular, cardiovascular, metabolic, and inflammatory co-morbidities (NU21-04-00445)

Deep brain stimulation (DBS) is an established treatment for late motor symptoms in Parkinson’s disease (PD). Although DBS is generally a successful therapy. The effect of DBS and disease progression is reflected by modulat...

Clinical neurology

  • 2021 - 2024
    • •
  • 11 803 tis. Kč
    • •
  • 11 803 tis. Kč
    • •
  • MZ
Project

Synthesis and application of Dewar benzenes in organic synthesis (IAA401110805)

The grant proposal concerns synthesis and application of Dewar benzenes (DB) in organic synthesis. Initially, new types of DB that will be used as building block and their application in cross-coupling reactions. The prepared DB...

CC - Organická chemie

  • 2008 - 2012
    • •
  • 5 000 tis. Kč
    • •
  • 5 000 tis. Kč
    • •
  • AV ČR
Project

Mechanisms of deep brain stimulation Role of the subthalamus in motor, visual and affective processing (GA309/09/1145)

Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) is an important the beneficial effects of STN DBS on motor functions, our knowledge of the neurostimulation, our proposed project is designed to study the STN DBS

FH - Neurologie, neurochirurgie, neurovědy

  • 2009 - 2012
    • •
  • 5 242 tis. Kč
    • •
  • 5 224 tis. Kč
    • •
  • GA ČR
Project

Pathophysiological mechanisms of neuromodulation therapy in dystonia (NT12282)

brain stimulation of the globus pallidus interna (GPi DBS) in dystonic patients will include analysis of DBS-induced long-term neuroplastic changes. We believe of dystonic involvement. The results are expected to improve our unders...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2015
    • •
  • 6 385 tis. Kč
    • •
  • 6 385 tis. Kč
    • •
  • MZ
Project

Reducing speech-related side-effects of deep brain stimulation in Parkinson's Disease via automated speech analysis (GF21-14216L)

Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an effective are equivocal. Although some aspects of speech might improve with STN-DBS, stimulation and quantitative evaluation of speech. Thus improvement of STN-DB...

Medical engineering

  • 2021 - 2023
    • •
  • 7 182 tis. Kč
    • •
  • 7 182 tis. Kč
    • •
  • GA ČR
Project

Clinical, Imaging and Biological predictors of effects associated with deep brain stimulation in Parkinson’s disease (NV19-04-00233)

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a common treatment for intermediate and late stages of Parkinson’s disease (PD). The development DBS. Among the ‘hard’ criteria that exclude patients from the DBS<...

Clinical neurology

  • 2019 - 2023
    • •
  • 14 978 tis. Kč
    • •
  • 14 894 tis. Kč
    • •
  • MZ
Project

Subcortical nuclei and cortical functions – insight from the deep brain stimulation perspective (GA21-25953S)

insufficiently explained. Deep brain stimulation (DBS) is an established treatment for late algorithms represents a new approach to study the impact of DBS on whole brain networks pathophysiology is necessary mainly in relation to ...

Clinical neurology

  • 2021 - 2023
    • •
  • 8 656 tis. Kč
    • •
  • 8 381 tis. Kč
    • •
  • GA ČR
Project

The use of deep-brain stimulation in treatment of Parkinson's disease and movement disorders (1A8629)

The projects aims to develop methods and indications of deep-brain stimulation (DBS) in Parkinson's disease and other movement disorders that cannot be controlled by classical pharmacotherapy. The effects of DBS on on motor and non-...

FH - Neurologie, neurochirurgie, neurovědy

  • 2005 - 2009
    • •
  • 12 956 tis. Kč
    • •
  • 12 582 tis. Kč
    • •
  • MZ
Project

MIcro and MAcro Connectomics of the Subthalamic nucleus in humans impact of neuromodulation and dopamine depletion (GA16-13323S)

The subthalamic nucleus (STN) is an important subcortical structure of the brain and a common target for deep brain stimulation (DBS) in the treatment of Parkinson’s disease. Despite its excellent effects on movement, STN DBS is acc...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2020
    • •
  • 9 921 tis. Kč
    • •
  • 9 612 tis. Kč
    • •
  • GA ČR
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