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11 540 (0,063s) •

Project

OncoDetect - system for early detection of cancer markers in peripheral blood of patients (TA02010672)

The project is directed at development of a prototype instrument for detection of tumor-specific DNA/RNA markers in peripheral blood of cancer patients. The system will be based on a combination of microfluidic reactor and separator...

EI - Biotechnologie a bionika

  • 2012 - 2016
    • •
  • 19 486 tis. Kč
    • •
  • 11 965 tis. Kč
    • •
  • TA ČR
Project

Mechanical properties of RNA and DNA structural building blocks (GA17-14683S)

Natural and artificial RNA and DNA structures are composed of recurrent of cytosine methylation on DNA mechanics, and DNA with structural lesions. In the RNA laboratories. The results will elucidate mechan...

BO - Biofyzika

  • 2017 - 2021
    • •
  • 4 017 tis. Kč
    • •
  • 3 756 tis. Kč
    • •
  • GA ČR
Project

Nanomechanics of RNA and DNA structural motifs (GA14-21893S)

RNA and DNA motifs are recurrent structural building blocks found dynamics (MD) simulation data of selected RNA and DNA molecules. We will adopt of RNA and DNA motifs important in cellular process...

BO - Biofyzika

  • 2014 - 2016
    • •
  • 2 668 tis. Kč
    • •
  • 2 668 tis. Kč
    • •
  • GA ČR
Project

The DNA Damage Response and RNA Processing in Neurological Disorders (GA25-15199S)

mutations, with particular emphasis on their roles in RNA processing and the DNA damage between DNA repair mechanisms, transcriptional stress, and RNA processingThe proposed project will investigate the intricate ...

Cell biology

  • 2025 - 2027
    • •
  • 11 910 tis. Kč
    • •
  • 11 910 tis. Kč
    • •
  • GA ČR
Project

Viral RNA modifications – Essential steps in Chemical Evolution of Protein Cofactors (LL1603)

analysis of RNA modifications enabling detailed studies of the chemical structure of various RNA entities are being developed only recently and they have never been) of mammalian viruses (DNA and RNA), ba...

CE - Biochemie

  • 2017 - 2021
    • •
  • 48 762 tis. Kč
    • •
  • 48 762 tis. Kč
    • •
  • MŠMT
Project

DNA chip technology for high-throughput mutation analysis and differential gene expression studies. (NM5888)

The aim of the project is to master all the basic techniques of DNA microarray technology and to used them for optimised preparation of series of various DNA arrays. Oligonucleotide arrays dedicated for a known mutation series will ...

FP - Ostatní lékařské obory

  • 2000 - 2001
    • •
  • 4 113 tis. Kč
    • •
  • 4 113 tis. Kč
    • •
  • MZ
Project

A functional assay for heterozygous mutations in the GTPase activating protein related domain of the neurofibromatosis type 1 gene (NM7627)

Completation of DNA bank of NF patients and establishment of RNA bank include verificated mutation in GRD region and in DNA sequence out of this region Aplication of optimalised FASAY method to established group of NF patie...

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 563 tis. Kč
    • •
  • 553 tis. Kč
    • •
  • MZ
Project

Theoretical calculations of the metal cations interactions with biomolecules (1P05ME784)

calculations o f complexes with base models of DNA/RNA and upper oligomeres...

BE - Teoretická fyzika

  • 2005 - 2007
    • •
  • 1 386 tis. Kč
    • •
  • 951 tis. Kč
    • •
  • MŠMT
Project

Simplified method for quantification of specific genes expression (FV20479)

for gene quantification is based on transcription of RNA into complementary DNA (cDNA and rapid ligation of DNA probes bound to RNA and followed by quantification enzymatic activity for ligation of DNA pr...

EB - Genetika a molekulární biologie

  • 2017 - 2020
    • •
  • 9 995 tis. Kč
    • •
  • 7 971 tis. Kč
    • •
  • MPO
Project

Improved diagnosis of muscular dystrophies using methods for identification of DGC proteins. (NM19)

Introduction of immunohistochemical methods as well as DNA/RNA analysis for differential diagnosis of muscular dystrophies, which could define dystrophinopathies and further alterations of the proteins of dystrophin-glycopr...

FH - Neurologie, neurochirurgie, neurovědy

  • 1998 - 2000
    • •
  • 3 603 tis. Kč
    • •
  • 3 535 tis. Kč
    • •
  • MZ
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