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1 904 (0,14s)

Project

Chemical modification and electrochemical analysis of nucleic acids as a new tool in molecular oncology (GA17-08971S)

are thus being developed, including those based on electrochemistry, which also offers to develop electrochemical assays for detection of DNA and RNA sequences, as well as for analysis of DNA methylation, an epigenetic mod...

CG - Elektrochemie

  • 2017 - 2019
  • 6 782 tis. Kč
  • 6 356 tis. Kč
  • GA ČR
Project

Electrochemistry in protein analysis and in detection of DNA hybridization (GA204/03/0566)

sensors of the DNA hybridization represent one of the most promising solution ofthis problem. This project is oriented to basic research in electrochemistry of DNA......

EI - Biotechnologie a bionika

  • 2003 - 2005
  • 4 207 tis. Kč
  • 2 737 tis. Kč
  • GA ČR
Project

Electroactive and fluorescent modifications of nucleic acids for structure & interaction studies and for applications in diagnostics (GA22-11252S)

Our recent findings in the areas of nucleic acid (NA) electrochemistry, new findings on electrocatalytic processes, establishing techniques of DNA to modify NA; (3) influence of specific DNA modifications on its structures ...

Analytical chemistry

  • 2022 - 2024
  • 11 476 tis. Kč
  • 11 215 tis. Kč
  • GA ČR
Project

Research and development of a new type of electrochemical biosensor for the detection of nucleotide sequences in DNA and of genotoxic agents in the environment. (1H-PK/42)

At present there is an increasing interest in devices (sensors, chips, etc.) suitable for rapid detection of a large number of nucleotide sequences in DNA and RNA, based on optical methods. It is the intention of this project to complement t...

EI - Biotechnologie a bionika

  • 2004 - 2007
  • 14 864 tis. Kč
  • 7 403 tis. Kč
  • MPO
Project

Nanotechnologies for protein and gene diagnostics (KAN400310651)

for analysis of DNA and proteins combining nanotechnology, microfluidics and electrochemistry. The research of the nanostructures will be directed towards surface enhanced will be focused on biosensors of DNA damage and on...

BO - Biofyzika

  • 2006 - 2010
  • 17 636 tis. Kč
  • 17 636 tis. Kč
  • AV ČR
Project

Electrochemical biosensor for analysis of DNA point mutations in colorectal cancer (NU21-08-00078)

and chemistries. Electrochemistry could be an interesting alternative due to its simplicity propose to develop a novel biomedical technology based on electrochemistry for detection of a panel of DNA point mutations in CRC....

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2021 - 2024
  • 7 649 tis. Kč
  • 7 649 tis. Kč
  • MZ
Project

Electrochemical methods for bioanalysis of nucleic acids and their application in cancer diagnostics (GP14-24931P)

for their analysis. For instance, alterations in microRNA expression and changes in DNA and carcinogenesis. Compared to currently used methods, electrochemistry is considered less) discrimination of methylated and unmethylated ...

BO - Biofyzika

  • 2014 - 2016
  • 1 956 tis. Kč
  • 1 956 tis. Kč
  • GA ČR
Project

New tools for research and diagnostics of diseases. Microfluidic reactors and electrochemistry for analysis of proteins and their glycosylation. (GA15-15479S)

This project deals with development of new tools for analysis of non-conjugated proteins and glycoproteins using combination of electrochemistry with microfluidics and enzymatic microreactors. The project is based on recent findings made in ...

CG - Elektrochemie

  • 2015 - 2017
  • 6 400 tis. Kč
  • 6 315 tis. Kč
  • GA ČR
Project

Recognizing DNA damage by Tumor Suppressor Proteins. Effects of Anti - Cancer Drugs. (NC7574)

of protein p53 (and its homologues) with damaged DNA will be studied. Our efforts of individual protein domains in DNA damage recognition, the effects of the protein selectively to damaged DNA will be compared. The ability...

FC - Pneumologie

  • 2003 - 2005
  • 2 921 tis. Kč
  • 2 004 tis. Kč
  • MZ
Project

Electrochemical tools for detection of point mutations and polymorphisms in DNA (GP203/08/P598)

on developing electrochemical tools for DNA hybridisation detection. We will jodidy behaviour and use them as signalling probes in DNA hybridization. OsO4 complexes will be used as chemical probes for unpaired and mispaired bases i...

CG - Elektrochemie

  • 2008 - 2010
  • 1 404 tis. Kč
  • 1 404 tis. Kč
  • GA ČR
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