Filters
Molekular analysis of hyperlipoproteinemias The influence of mutations in the genes for LDLreceptor, apoB-100 and apoE on the phenotype of FH and FDB (NE5554)
The main goal of the project is to determine pathological DNA mutations for the three candidate genes, contributing to origin and development of atherosclerosis and their correlation with phenotypic manifestation. It is generally accepted,th...
EB - Genetika a molekulární biologie
- 1999 - 2001 •
- 3 696 tis. Kč •
- 3 696 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1999 - 1. 1. 2001
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Faecal bacteriotherapy for ulcerative colitis (NV16-27449A)
FB focusing on bacterial DNA sequencing to identify the bacterial species which...
FE - Ostatní obory vnitřního lékařství
- 2016 - 2020 •
- 6 517 tis. Kč •
- 6 418 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2016 - 31. 12. 2020
Uznané náklady
Podpora ze státního rozpočtu (98%)
Poskytovatel: Ministerstvo zdravotnictví
The role of CD36 gene in pathogenesis of Alzheimer´s disease (NV18-04-00455)
The project is focused on the role of CD36 gene in the pathogenesis of cognitive disorders. It is based on our recent discovery of a significant association between CD36 gene and Alzheimer’s disease (AD). CD36 is involved in the removal of amyloid ß ...
Clinical neurology
- 2018 - 2021 •
- 11 992 tis. Kč •
- 11 992 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2018 - 31. 12. 2021
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Advanced sequencing methods for deciphering structural variants in cancer genome (NU21-08-00237)
lesions. Long-read sequencing is a technique that can read kilobases long DNA sequences, providing detailed information about primary DNA structure and genomic......
Human genetics
- 2021 - 2025 •
- 12 671 tis. Kč •
- 12 671 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2021 - 31. 12. 2025
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Deepening our knowledge about the aetiopathogenesis of Malignant Hyperthermia (MH) and streamlining the diagnostic algorithm MH for the Czech population (NU21-06-00363)
Malignant Hyperthermia (MH) is a rare life-threatening pharmacogenetic disease triggered by some commonly used anaesthetics. Its incidence is reported to be in the range of 1:10,000 to 1:250,000 anaesthesia. A fully developed form of MH can result in...
Anaesthesiology
- 2021 - 2024 •
- 10 692 tis. Kč •
- 10 692 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2021 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Applications of chemical structural probes and electroanalytical methods in DNA damage detection. Development of DNA sensors. (KJB4004302)
In this project we propose to employ chemical probing of DNA structure, in connection with biochemical methods and electrochemical detection, in analysis of DNA damage. Monitoring of DNA-damaging pollutants in the environme...
CG - Elektrochemie
- 2003 - 2005 •
- 2 052 tis. Kč •
- 1 212 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (59%)
Poskytovatel: Akademie věd České republiky
Translesion DNA synthesis across lesions induced by agents of biological significance. An insight into energetics, kinetics and mechanism (GA17-09436S)
The biological effects of DNA-damaging physical and chemical agents are associated with their ability to affect DNA replication. The main objective of DNA due to its damage by DNA-damaging agents is an important fa...
BO - Biofyzika
- 2017 - 2019 •
- 5 627 tis. Kč •
- 5 006 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2017 - 31. 12. 2019
Uznané náklady
Podpora ze státního rozpočtu (89%)
Poskytovatel: Grantová agentura České republiky
Interactions of wild type and mutant p53 proteins with damaged DNA and their roles in cellular response to anticancer chemotherapy (IAA500040701)
Interactions of tumor suppressor protein p53 with DNA are crucial for its-specific DNA binding, but also ability of both wt and mutant (mut) p53 to recognize DNA and mut p53 interactions with damaged DNA, particula...
EB - Genetika a molekulární biologie
- 2007 - 2010 •
- 4 824 tis. Kč •
- 4 824 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2007 - 31. 12. 2010
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Akademie věd České republiky
Development of electrochemical biodetectors for DNA damage (IAA4004108)
electrochemical biodetector (biosensor) for DNA damage (both in vitro and in cells) and DNA damaging agents. A procedure developed in our laboratory which allows to detect DNA strand breaks using mercury electrodes modifie...
CG - Elektrochemie
- 2001 - 2003 •
- 1 758 tis. Kč •
- 804 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2001 - 1. 1. 2003
Uznané náklady
Podpora ze státního rozpočtu (46%)
Poskytovatel: Akademie věd České republiky
Extrachromosomal circular DNA and its impact on the evolution of plant satellite DNA (GP204/06/P360)
Satellite DNA formed by long arrays of repetitive tandemly arranged nucleotide recombination between repetitive units leading to formation of circular satellite DNA could extrachromosomal circular DNA with special impact on...
EB - Genetika a molekulární biologie
- 2006 - 2008 •
- 947 tis. Kč •
- 947 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2006 - 31. 12. 2008
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
- 1 - 10 out of 1 792