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2 051 (0,085s)

Project

Novel approaches towards anti - HIV -1 DNA vaccine (ME 875)

study of biodistribution of DNA/Gal-lipolex complexes and immunity response to gp120+MBLDNA/Gal-lipolex immunisation, comparison of HIV-- glycosylation concensus B gp 120 antigene exprimed in different tissue cells......

EC - Imunologie

  • 2006 - 2009
  • 1 785 tis. Kč
  • 1 685 tis. Kč
  • MŠMT
Project

Vectors for gene therapy targeted on stromal cells of solid tumors (NR9238)

Investigation of an anti-tumor therapeutic DNA vaccine and vectors for gene virus HPV16. DNA vaccine will provide immunization against fibroblast activating protein (FAP).Vaccine will be combined with ...

FD - Onkologie a hematologie

  • 2007 - 2009
  • 9 764 tis. Kč
  • 9 542 tis. Kč
  • MZ
Project

Development of vaccines against markers of cancer stem cells (NT11541)

Development of DNA vaccines against transcription factors SOX2 and NANOG induced with the constructed DNA vaccines by in vitro tests and by observation of immunogenicity of these vaccines by the addition o...

FD - Onkologie a hematologie

  • 2010 - 2013
  • 9 263 tis. Kč
  • 9 263 tis. Kč
  • MZ
Project

Combined Immunotherapy of Tumours Induced by Human Papillomavirus (NR8004)

The aim of the project is to develop an immunotherapeutic procedure against papilloma virus-associated tumours employing prime/boost strategy. The approach combines heterologous vaccines. They include DNA vaccines, recombin...

FD - Onkologie a hematologie

  • 2004 - 2006
  • 13 021 tis. Kč
  • 10 895 tis. Kč
  • MZ
Project

Utilization of centrosomal proteins for prognostication and vaccinotherapy of chronic myeloid leukemia (NT13862)

) and development of DNA vaccines against this disease based on increased production of therapy. Development of DNA vaccines against HMMR and AURKA that should be efficient against CML stem cells resistant to imati...

FD - Onkologie a hematologie

  • 2012 - 2015
  • 9 681 tis. Kč
  • 9 681 tis. Kč
  • MZ
Project

Development of vectors, carriers and adjuvants for the constructoin of DNA vaccines (QF3115)

after vaccination and steer it into desired type of response. Construction of DNA-vaccines against mentioned diseases....

EC - Imunologie

  • 2003 - 2007
  • 11 010 tis. Kč
  • 11 010 tis. Kč
  • MZe
Project

*Development of the recombinant vaccine against poultry coccidiosis. (FI-IM/056)

*Development of recombinant vaccine or therapeutical protein substances against pouldry coccidiosis. Sophisticated "postgenomic" technique the DNA microarray" will be applied to analyze gene expression in the unique attenuated lineo...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2004 - 2006
  • 27 164 tis. Kč
  • 12 813 tis. Kč
  • MPO
Project

Comparison of a Recombinant hsp90 Protein Vaccine and DNA Vaccine Protectivity in Mouse Vaginal and Systemic Candidiasis Model (NI7538)

evidences that the anti-hsp response is protective. Consequently hsp90 vaccination...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2003 - 2005
  • 2 141 tis. Kč
  • 2 101 tis. Kč
  • MZ
Project

Imunization against Tumors Characterized by Different Escape Mechanisms (NC7552)

Imunization against mouse tumor cells with reduced expression of MHC class I molecules and /or tumor antigen (oncoprotein E7 of human papillomavirus type 16). Utilization of DNA vaccines, cellular vaccines and recombinant a...

FD - Onkologie a hematologie

  • 2003 - 2005
  • 12 151 tis. Kč
  • 11 594 tis. Kč
  • MZ
Project

The prevalence of HPV infections in the vaccinated population of women in the Czech Repuublic (NT12372)

of HPV DNA in cervical smear and type-specific antibodies against vaccinal HPV typesin blood. Monitoring of the vaccine efficacy for the protection of a consequent infection with vaccinal or closely related types ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2011 - 2014
  • 3 042 tis. Kč
  • 3 042 tis. Kč
  • MZ
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