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81 (0,093s) •

Project

The use of human genes for metabolising enzymes in genotoxicity testing in transgenic Drosophila melanogaster (GA302/96/1393)

There are the commonly used genotoxicity tests of chemicals and environmental pollutants. Transformation of human genes for metabolising enzymes to Drosophila melanogaster which are able to detoxificate xenobiotics can increase the significa...

EB - Genetika a molekulární biologie

  • 1996 - 1998
    • •
  • 858 tis. Kč
    • •
  • 828 tis. Kč
    • •
  • GA ČR
Project

Adenosine deaminase homologs in Drosophila (IAA5007107)

insight into this function, we will exploit the Drosophila genetic cystem to conduct homolog in flesh-fly showed that this protein works as growth factor. In Drosophila of these Drosophila genes. This analysis will include...

EB - Genetika a molekulární biologie

  • 2001 - 2005
    • •
  • 3 878 tis. Kč
    • •
  • 1 998 tis. Kč
    • •
  • AV ČR
Project

Roles of extracellular adenosine in hematopoiesis and innate immunity using Drosophila as a model to study these roles in vivo (KJB501410602)

the mechanism of such effects is often unclear, we have established a Drosophila model is the main regulator of adenosine levels in Drosophila, and use it to study the role of the Drosophila model ? large mutagenesis scree...

EB - Genetika a molekulární biologie

  • 2006 - 2008
    • •
  • 1 925 tis. Kč
    • •
  • 1 925 tis. Kč
    • •
  • AV ČR
Project

The role of sirtuins in Notch signalling and Drosophila development (GA14-08583S)

for the Notch pathway. Our own data suggest that the role of Sir2 (the Drosophila ortholog status. We propose (1) to identify binding partners of all 5 Drosophila sirtuins imaging of the NAD+:NADH status during Drosophila ...

EB - Genetika a molekulární biologie

  • 2014 - 2016
    • •
  • 4 560 tis. Kč
    • •
  • 4 560 tis. Kč
    • •
  • GA ČR
Project

Genetic Analysis of Drosophila Growth Factors (GA204/01/1022)

This proposal concerns the mode of action and properties of a family of five growth factors isolated from Drosophila melanogaster. Three of these factors known as imaginal disc growth factors (IDGF1-3) are encoded by three genes in a small c...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 2 961 tis. Kč
    • •
  • 1 761 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanism within the Pax6 pathway controlling eye development (GA204/99/0105)

developmental program of the organ (eye) in organisms as divergent as human and Drosophila. Mutations in Drosophila Pax6/eyless gene as well as in the mouse or the human Pax6 genes), whereas misexpression of the Drosophila...

EB - Genetika a molekulární biologie

  • 1999 - 2001
    • •
  • 3 000 tis. Kč
    • •
  • 2 591 tis. Kč
    • •
  • GA ČR
Project

Architecture of an Ancestral Insect Clock – Surprising Combination of Mammalian and Drosophila Genetic Components (GC14-32654J)

of circadian clocks is best understood in a few models. Mouse and Drosophila share most differ from Drosophila and surprisingly share some important similarities will be functionally tested in transgenic Drosophila studies...

EB - Genetika a molekulární biologie

  • 2014 - 2016
    • •
  • 7 778 tis. Kč
    • •
  • 7 778 tis. Kč
    • •
  • GA ČR
Project

Functions of adenosine signaling in organism (GA14-27816S)

signaling and metabolism are conserved across phyla. Drosophila has only a single Ado of adenosine receptor deficiency in Drosophila, and to examine evolutionary conservation of adenosine signaling function between Drosophila

EB - Genetika a molekulární biologie

  • 2014 - 2016
    • •
  • 6 357 tis. Kč
    • •
  • 6 357 tis. Kč
    • •
  • GA ČR
Project

Drosophila habituation to close the gap in genetic diagnostics of neurodevelopmental disorders (GA23-07810S)

impair ID/ASD-relevant cognitive function is needed. I propose Drosophila of learning that is widely affected in ID/ASD individuals and Drosophila models to help......

Genetics and heredity (medical genetics to be 3)

  • 2023 - 2025
    • •
  • 8 431 tis. Kč
    • •
  • 8 431 tis. Kč
    • •
  • GA ČR
Project

Monitoring protein-protein interactions in vivo (IAA500960802)

such technique in genetic and molecular model organism Drosophila melanogaster. We beyond the Drosophila research....

EB - Genetika a molekulární biologie

  • 2008 - 2012
    • •
  • 4 084 tis. Kč
    • •
  • 4 084 tis. Kč
    • •
  • AV ČR
  • 1 - 10 out of 81