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1 521 (0,078s) •

Project

Study on mechanisms of selected drug-drug interactions in oncology (NR9206)

The aim of the project is to elucidate selected drug-drug interactions in several pharmacotherapeutic groups. Based on results, we will predict further interactions of studied drugs and suggest optimisation of current chemo...

FR - Farmakologie a lékárnická chemie

  • 2007 - 2009
    • •
  • 4 068 tis. Kč
    • •
  • 3 831 tis. Kč
    • •
  • MZ
Project

Interactions of antiretroviral drugs with human drug transporters in vitro in consideration of transplacental pharmacokinetics (GP13-31118P)

the advantage of combination of various antiretroviral drugs, which target HIV-1 virus of transporters affecting drug transfer from mother to fetus. They include drug efflux to pharmacokinetic drug-drug i...

FR - Farmakologie a lékárnická chemie

  • 2013 - 2016
    • •
  • 1 883 tis. Kč
    • •
  • 1 883 tis. Kč
    • •
  • GA ČR
Project

In vitro and ex vivo models to study drug-drug interactions of antiviral drugs on intestinal transporters (GJ18-07281Y)

Most of drugs today are administrated orally and thus reach the systemic influenced by the activity of drug efflux and uptake transporters. Pharmacokinetic drug-drug interactions (DDIs) on these transporters may th...

Pharmacology and pharmacy

  • 2018 - 2022
    • •
  • 4 967 tis. Kč
    • •
  • 4 967 tis. Kč
    • •
  • GA ČR
Project

Atomistic description of ABCC4/MRP4 membrane transporter towards clinical applications (7AMB17FR026)

and to predict the clinically observed drug resistance, drug toxicity, pharmacogenomics and drug-drug interactions.......

FR - Farmakologie a lékárnická chemie

  • 2017 - 2018
    • •
  • 108 tis. Kč
    • •
  • 108 tis. Kč
    • •
  • MŠMT
Project

Stochastic models of dissolution, residence time and drug-receptor interaction in pharmacokinetics (NL6431)

To propose statistical methods for inference on dissolution data from non homogenous drugs. To devise a method for optimum drug administration in stochastic multicompartment system. To deduce time-profile of drug action in ...

FR - Farmakologie a lékárnická chemie

  • 2001 - 2003
    • •
  • 2 027 tis. Kč
    • •
  • 618 tis. Kč
    • •
  • MZ
Project

Determination of the amount of illicit drugs and their metabolites in municipal wastewater - new tool for obtaining of complementary data on illicite drug consumption in the Czech Republic (VG20122015101)

The new data set about use of illicit drugs in the Czech Republic will be obtained. The Aplication of analytical method for determination of illicit drugs unit for effective dose per person for each drug for sampled area. T...

CB - Analytická chemie, separace

  • 2012 - 2015
    • •
  • 14 681 tis. Kč
    • •
  • 14 681 tis. Kč
    • •
  • MV
Project

The need and consumption of drugs in hospital (NL4891)

Development of a specific procedure to achieve a balance between drug costs and benefits of pharmacotherapy in the hospital setting. Data of drug requirements are constantly evaluated using the ongoing drug consumption revi...

FR - Farmakologie a lékárnická chemie

  • 1998 - 2000
    • •
  • 1 893 tis. Kč
    • •
  • 1 565 tis. Kč
    • •
  • MZ
Project

Active drug-seeking behavior in prenatally methamphetamine-exposed adult male and female rats (NS10509)

methamphetamine (MA) exposure on drug-seeking behavior in adulthood. The following drugs will be tested: (1) the same drug as prenatally (MA); (2) the related drugs (amphetamine, cocaine, MDMA); (3) the unrelated ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2009 - 2011
    • •
  • 3 151 tis. Kč
    • •
  • 3 151 tis. Kč
    • •
  • MZ
Project

Identification of abused drugs by GC-MS method (MO66080398204)

Preparation, establishment and verification of the methods for identification and quantification with the GC-MS analyzer at 4-5 groupsof abuse drugs. Analysis of the tresholds and positives result from the abuse drugs screening of u...

FP - Ostatní lékařské obory

  • 1998 - 2000
    • •
  • 993 tis. Kč
    • •
  • 993 tis. Kč
    • •
  • MO
Project

Analysis of the efectivity of the minimal drug preventive progremmes on Basic schools (LS012940)

Analysis of the efectivity of the minimal drug preventive programmes on Basic schools and conparison of these methods from the point of view of the drug preventers and pupils and fullfilment on the existing data creating a method of...

AM - Pedagogika a školství

  • 2001 - 2002
    • •
  • 360 tis. Kč
    • •
  • 360 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 1 521