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393 (0,114s) •

Project

Transformations of the gastrointestinal stem cell niche during the development and regeneration (GA21-26025S)

Recent data suggest re-acquiring of embryonic features during the progression of colon cancer and intestinal regeneration. Additionally, intestinal epithelial stem cells change their signature from embryonic to adult one during the ...

Cell biology

  • 2021 - 2023
    • •
  • 8 487 tis. Kč
    • •
  • 8 487 tis. Kč
    • •
  • GA ČR
Project

The role of ATF2 transcription factor in development and homeostasis of colon and its involvement in progression of colorectal carcinoma (LTAB19002)

1) Characterisation of lethal phenotype in ATF2 KO mouse model 2) Mapping of ATF2 expression during development and in adult tissues 3) Distinguishing tissue specific roles (Inducible Knock out startegy) 4) Molecular context of ATF2 in intestine d...

Genetics and heredity (medical genetics to be 3)

  • 2019 - 2021
    • •
  • 1 200 tis. Kč
    • •
  • 1 200 tis. Kč
    • •
  • MŠMT
Project

Functional evolution of termite gut microbiome (GA20-20548S)

Termites harbor a large number of symbiotic microbes in their gut. Gut microbes will address this question using the gut metagenomes of a representative set of 250 termite of the gut microbiome of an insect order. ...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2020 - 2022
    • •
  • 7 534 tis. Kč
    • •
  • 7 534 tis. Kč
    • •
  • GA ČR
Project

Activation of Chk1 and Chk2 kinases in response to stress in mouse embryonic stem cells. (NR9508)

Study of activation of Chk1 and Chk2 kinases in G1 checkpoint in mouse embryonic stem cells. Characterization of kinases involved in regulation of G1 checkpoint in mouse embryonic stem cells. Study of influence of an active oncoprot...

FD - Onkologie a hematologie

  • 2007 - 2009
    • •
  • 2 774 tis. Kč
    • •
  • 2 771 tis. Kč
    • •
  • MZ
Project

Soil invertebrate-microbial interaction during the gut passage and their role in plant litter transformation (IAB6066903)

of leaf litter and its gut passage. The study of invertabrate-microbial interaction during gut passage using whole system manipulation is difficult because of complexity of wide spectrum of parameters during the gut passag...

EG - Zoologie

  • 1999 - 2001
    • •
  • 1 062 tis. Kč
    • •
  • 629 tis. Kč
    • •
  • AV ČR
Project

Nutrition of the burn trauma - test of the gut permeability (MO66021299115)

Test of the gut permeability in burn trauma with LAMA test. Get the test to the real life. Improvement of effectivity of treatment....

FI - Traumatologie a ortopedie

  • 1999 - 2001
    • •
  • 283 tis. Kč
    • •
  • 283 tis. Kč
    • •
  • MO
Project

Gut microbiota and the role of food additives in the development of allergies and autoimmune diseases (GA15-09518S)

. According to current knowledge the abnormal composition of gut microbiota characterized important environmental factor influencing the composition of gut microbiota. We of additives on the gut microbiome we exploit a mode...

EC - Imunologie

  • 2015 - 2019
    • •
  • 5 688 tis. Kč
    • •
  • 5 688 tis. Kč
    • •
  • GA ČR
Project

Gut fungal microbiota mechanisms of action in pathogenesis of inflammatory bowel disease (GJ17-06632Y)

Gut microbiota plays significant role in the pathogenesis of gastrointestinal influence development and course of the disease. We hypothesize that alteration of gut mycobiota by diet, treatment or disease can impair gut bar...

EC - Imunologie

  • 2017 - 2021
    • •
  • 3 913 tis. Kč
    • •
  • 3 913 tis. Kč
    • •
  • GA ČR
Project

Diet and microbiota as modulators of gut inflammation and colon cancer (GA16-06326S)

Republic particularly. Its association with gut inflammation and activity of resident microbiota has been recently suggested. Gut microbiota is metabolically active part products that can impair gut barrier functions and p...

EC - Imunologie

  • 2016 - 2020
    • •
  • 7 179 tis. Kč
    • •
  • 6 909 tis. Kč
    • •
  • GA ČR
Project

Functional interaction between host gene regulation and the microbiome in the primate gut (LH15175)

The gut microbiome plays a vital role in the host physiological landscape (e.g. diet) are important drivers of gut microbiome composition in humans will characterize relationships between diets, intestinal gene expression markers at...

EE - Mikrobiologie, virologie

  • 2015 - 2017
    • •
  • 1 997 tis. Kč
    • •
  • 1 997 tis. Kč
    • •
  • MŠMT
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