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3 306 (0,228s) •

Project

Engineering radionuclide - labeled antibodies (OE 210)

production of prototype radioimunological agent based on protein-engineered antibody with required combination of desirable properties......

EC - Imunologie

  • 2006 - 2009
    • •
  • 18 186 tis. Kč
    • •
  • 9 093 tis. Kč
    • •
  • MŠMT
Project

Preparation of new radiopharmaceuticals based on monoclonal and recombinant antibodies and peptides labelled by alpha and beta radionuclides (IBS1048301)

A. Choice of approppriate monoclonal antibodies (MABs) and their scFv fragments, an antibody against neuron-specific tubuline, MEM-97, an antibody specific for leukocyte antigen (CD20). B. Development of methods for alpha-<...

CH - Jaderná a kvantová chemie, fotochemie

  • 2003 - 2005
    • •
  • 7 375 tis. Kč
    • •
  • 3 731 tis. Kč
    • •
  • AV ČR
Project

Labelling of monoclonal antibodies with At-211 for targeted cancer therapy (KJB4048302)

of the product, and the investigation of several labelling methods for astatination of a model monoclonal antibody and their comparison with respect to the labelling yieldRadionuclide AT-211 is one of a few promis...

CH - Jaderná a kvantová chemie, fotochemie

  • 2003 - 2005
    • •
  • 1 656 tis. Kč
    • •
  • 1 336 tis. Kč
    • •
  • AV ČR
Project

Development of terbium-161-labelled biomolecules as theranostic tools in nuclear medicine (NU23-08-00214)

various receptors expressed in cancer tissues. The antibodies will be labelled either will be performed. The forms of antibodies labelled with terbium-161 with adequateSelected radionuclides have been suc...

Pharmacology and pharmacy

  • 2023 - 2026
    • •
  • 12 656 tis. Kč
    • •
  • 12 656 tis. Kč
    • •
  • MZ
Project

Radionuclide precursors for synthesis of new radiopharmaceuticals for therapeutic applications (1QS100480501)

of selected monoclonal antibodies labelled with Y-90 will be then studied. Chitosan radiation load of few tens to hundreds of GBq of á-radionuclides. The resulting no-carrier-added Y-90 will be used to investigate stabilit...

CH - Jaderná a kvantová chemie, fotochemie

  • 2005 - 2009
    • •
  • 8 972 tis. Kč
    • •
  • 8 972 tis. Kč
    • •
  • AV ČR
Project

New generation of reagents for diagnostic radioimmunoassays_2 (OE67/2)

Aim of the project is to develop novel derivates of monoclonal antibodies as diagnostic RIA reagents. Single-chain Fv fragments (scFvs) produced in E.coli will provide the access to their engineering towards better labelling

FP - Ostatní lékařské obory

  • 2000 - 2002
    • •
  • 4 088 tis. Kč
    • •
  • 1 838 tis. Kč
    • •
  • MŠMT
Project

Production of positron emitting radionuclides Y-86 and I-124 for PET-imaging, study of their separation from the irradiated matrix and labelling of chosen prospective carriers (2B06165)

of the project is the use of the produced radionuclides for the labelling studies. These two radionuclides are very promising tools for imaging of the metabolic, monoclonal antibodies, aminonucleosides and chelato...

CF - Fyzikální chemie a teoretická chemie

  • 2006 - 2011
    • •
  • 25 623 tis. Kč
    • •
  • 23 078 tis. Kč
    • •
  • MŠMT
Project

New generation of reagents for diagnostic radioimmunoassays_1 (OE67/1)

Aim of the project is todevelop novel derivates of monoclonal antibodies as diagnostic RIA reagents. Single-chain Fv fragments (scFvs) produced in E.coli will provide the access to their engineering towards better labelling...

FP - Ostatní lékařské obory

  • 2000 - 2002
    • •
  • 5 738 tis. Kč
    • •
  • 2 338 tis. Kč
    • •
  • MŠMT
Project

Research and development of diagnostic and therapeutic radionuclidic preparations based on monoclonal antibodies and synthetic peptides (FD-K/112)

Development and production of new type of radiopharmaceuticals based on use of specific quality of peptides and monoclonal antibodies to be bound to receptors of organs and especially tumours. Modern biotechnologies are supposed to be used f...

CH - Jaderná a kvantová chemie, fotochemie

  • 2001 - 2003
    • •
  • 10 545 tis. Kč
    • •
  • 4 600 tis. Kč
    • •
  • MPO
Project

Production of radionuclides on the reconstructed LWR-15 reactor (GV104/97/S066)

The project solves the preparation of promising radionuclides at specific to radionuclides for therapeutic purposes, generator systems and closed radioactivity of target materials, neutron oeld dosimetry, radionuclide separ...

CH - Jaderná a kvantová chemie, fotochemie

  • 1997 - 2001
    • •
  • 19 853 tis. Kč
    • •
  • 5 600 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 3 306