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343 (0,06s) •

Project

Enzymatic synthesis of multivalent glycoconjugates of natural and biologically active compounds. (LD13042)

The aim of the project is an elaboration of the methods of selective enzymatic glycosylation of multivalent glycomimetics (based on the thiourea-linked glycosides) and methodics of enzymatic glycosylation of the ph...

CE - Biochemie

  • 2013 - 2015
    • •
  • 1 442 tis. Kč
    • •
  • 1 442 tis. Kč
    • •
  • MŠMT
Project

Separation of N-acetylhexosamine-containing carbohydrates using physico-chemical and enzymatic methods (KJB400200601)

glycosylation)will be developed and optimised. Futhermore, complementary enzymatic methodsThe project aims at developing novel semipreparatory method for separation of isobaric glycosides composed of N-acetylhexosamines based on co...

CE - Biochemie

  • 2006 - 2006
    • •
  • 398 tis. Kč
    • •
  • 398 tis. Kč
    • •
  • AV ČR
Project

New enzymes and methods for chemoenzymatic synthesis of bioactive glycosides (GA203/01/1018)

Novel methods for enzymatic synthesis of bioactive glycosides based on aminosugars will be developed. New reaction conditions will be tested in enzymatic glycosylation to improve effectiveness of these reactions. New enzyme...

CE - Biochemie

  • 2001 - 2003
    • •
  • 6 664 tis. Kč
    • •
  • 3 794 tis. Kč
    • •
  • GA ČR
Project

New Enzymes and Selective Methods for Glycosidase-Catalysed Synthesis of Bioactive Glycosides and Glycomimetics (OC D25.002)

of enzymatic glycosylations will be increased using partly protected sugars will be created. Novel methods for enzymatic synthesis of bioactive glycosides liquids, high salt concentrations. New reaction conditions will be ...

CE - Biochemie

  • 2002 - 2006
    • •
  • 2 636 tis. Kč
    • •
  • 1 726 tis. Kč
    • •
  • MŠMT
Project

Role of prenylation and glycosylation patterns in anti-inflammatory activity and metabolism of natural phenolic compounds (GA23-04655S)

or in parallel glycosylated phenols are limited, and information on their metabolism and bioactivity is insufficient. Both prenylation and selective glycosylation may slow down degradation in the gut and increase bioavailability. C...

Plant sciences, botany

  • 2023 - 2025
    • •
  • 13 963 tis. Kč
    • •
  • 13 963 tis. Kč
    • •
  • GA ČR
Project

Enzymatic glycosylation of phenolic and polyphenolic substances. (7AMB13AR005)

The diglycosidase a-rhamnosyl-b-glucosidase from Acremonium and/or from other fungal sources will be purified and characterized from the proteomic point of view. a-Rhamnosidase from fungal producers will be cloned to be used as alternative to the dig...

CE - Biochemie

  • 2013 - 2014
    • •
  • 319 tis. Kč
    • •
  • 319 tis. Kč
    • •
  • MŠMT
Project

Chemoinformatics for glycosynthesis (LD13024)

The major drawback of enzymatic synthesis of oligosaccharides and glycoconjugates is a lack of understanding of factors determining which substrate is suitable of molecules and their reactivity in enzymecatalysed glycosylations. Thi...

CE - Biochemie

  • 2013 - 2015
    • •
  • 1 305 tis. Kč
    • •
  • 1 305 tis. Kč
    • •
  • MŠMT
Project

a-N-Acetylgalaktosaminidase - preparation, functional characterization and its application in chemoenzymatic synthesis (GP203/06/P146)

as the first carbohydrate unit to Ser and/or Thr will be prepared by enzymatic glycosylation (reversed glycosylation and transglycosylation reactions)using this enzyme......

CE - Biochemie

  • 2006 - 2008
    • •
  • 393 tis. Kč
    • •
  • 393 tis. Kč
    • •
  • GA ČR
Project

New tools for research and diagnostics of diseases. Microfluidic reactors and electrochemistry for analysis of proteins and their glycosylation. (GA15-15479S)

This project deals with development of new tools for analysis of non-conjugated proteins and glycoproteins using combination of electrochemistry with microfluidics and enzymatic microreactors. The project is based on recent findings made in ...

CG - Elektrochemie

  • 2015 - 2017
    • •
  • 6 400 tis. Kč
    • •
  • 6 315 tis. Kč
    • •
  • GA ČR
Project

New methods of analysis of proteins and their glycosylation in cancer - combination of electrochemistry, microfludic biosensors and mass spectrometry. (GAP301/11/2055)

New methods for analysis of proteins and their glycosylation in cancer.Combination of electrochemistry, microfluidic biosensors and mass spectrometry.The proposed work deals with studies of chemical modifications and interactions of proteins...

CG - Elektrochemie

  • 2011 - 2014
    • •
  • 14 986 tis. Kč
    • •
  • 14 986 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 343