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Projects

3 462 projects (0,181s)

Project

New molecular markers for monitoring of residual disease in acute myeloid leukemia patients (NS10632)

New molecular markers for monitoring minimal residual disease in patients with acute myeloid leukemia (AML). Quantitative determination of gene expression, mutation, and methylation in samples from AML patients. Evaluation of correl...

FD - Onkologie a hematologie

  • 2009 - 2011
  • 7 576 tis. Kč
  • 7 576 tis. Kč
  • MZ
Project

Development of molecular-genetic markers for modern breeding and gene engineering of hop (Humulus lupulus) based on the system of genomic and expression libraries. (QH81052)

of genomic and expression libraries of Czech hop. The new marker system will be verifiedThe project aims to develop molecular-genetic markers for modern selection proposed the classical system of marker-assisted s...

EB - Genetika a molekulární biologie

  • 2008 - 2012
  • 5 180 tis. Kč
  • 4 920 tis. Kč
  • MZe
Project

Influence of some lymphocyte subpopulations and markers of thrombocyte activation to the clinical progress of preeclampsia (NR8906)

The objective of this project is to determine expression of some subpopulations of lymphocytes which influence the damage of endothelium and markers of thrombocyte activation and their influance om the degree of preeclampsia.......

FK - Gynekologie a porodnictví

  • 2006 - 2008
  • 1 804 tis. Kč
  • 1 703 tis. Kč
  • MZ
Project

Study of mechanism of action of biomarkers correlating with breast cancer therapy outcome (NT13679)

Validation of differences in expression of previously identified genetic markers between patients with breast carcinoma treated by standard, mainly neoadjuvant chemotherapy, will be the main goal of this project. Markers re...

FR - Farmakologie a lékárnická chemie

  • 2012 - 2015
  • 7 131 tis. Kč
  • 6 897 tis. Kč
  • MZ
Project

Development of technologies for early detection of tick borne encephalitis, based on changes in gene expression and protein production in infected antigen-presenting cells (LTARF18021)

In the frame of the project, differential gene expression and protein production will be analysed in antigen-presenting cells during infection by the tick-borne encephalitis virus. The differentially expressed genes and proteins wil...

Microbiology

  • 2018 - 2021
  • 7 836 tis. Kč
  • 7 836 tis. Kč
  • MŠMT
Project

Study of genetic factors correlating with prognosis of breast carcinoma (NT14055)

candidate markers will be studied by correlation of gene expression with protein level or predictive marker. Breast tumor cell line models differing in expression of hormonalValidation of differences in gene e...

EB - Genetika a molekulární biologie

  • 2013 - 2015
  • 5 092 tis. Kč
  • 5 092 tis. Kč
  • MZ
Project

Expression pattern of WT1 gene isoforms and mutational status as a new pathogenetic and diagnostic marker in paediatric haematological malignancies (NS10488)

WT1 gene is potentially an important marker with hematological malignancies. Its role in malignant and normal cells is presumably influenced by the expression original methodology we will identify expression patterns of WT1...

FD - Onkologie a hematologie

  • 2009 - 2011
  • 5 270 tis. Kč
  • 5 270 tis. Kč
  • MZ
Project

p63 and p73 proteins as predictive markers in clinical oncology. (NT14602)

triple-negative breast carcinoma. Inducible expression of p63 protein in this cell. In the tumor biopsies, we will analyze the expression of p63 and p73 on the mRNA level) and immunochemical methods. The expression levels ...

FD - Onkologie a hematologie

  • 2013 - 2015
  • 4 961 tis. Kč
  • 4 961 tis. Kč
  • MZ
Project

New markers of development of colorectal carcinoma in ulcerative colitis patients (1A8651)

Quantification of genes responsible to inflammation and carcinogenesis Correlation of some genes expression to clinical and morphology of ulcerative colitis Cascade of chronic inflammation-dysplasia-colorectal carcinoma in experimental model...

EB - Genetika a molekulární biologie

  • 2005 - 2008
  • 4 053 tis. Kč
  • 3 992 tis. Kč
  • MZ
Project

Transcription of differentiation- specific genes and expression of neuroendocrine markers in small- cell lung carcinoma and some neuroectodermal tumors. (IZ952)

9F - 9

  • 1992 - 1995
  • 750 tis. Kč
  • 1 500 tis. Kč
  • MZ
  • 1 - 10 out of 3 462