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194 (0,098s) •

Project

Analysis of the effects of Cd36 (fat) transgene in spontaneously hypertensive rats on clustering of cardiovascular risk factors (GA301/00/1636)

of CD36, a key protein of the cellular transport of fatty acids; 2)CD36 is located ontoSHR background restores normal expression of CD36 and improves cellular defects provided a strong evidence for the involvement of C...

EB - Genetika a molekulární biologie

  • 2000 - 2002
    • •
  • 2 780 tis. Kč
    • •
  • 1 919 tis. Kč
    • •
  • GA ČR
Project

Nutritional and hormonal regulation of synthesis and transport fatty acids in insulin resistance (NR7888)

of Cd36 fatty acid transporter and transgenic SHR rats with expression of Cd36 or aP2...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2006
    • •
  • 5 556 tis. Kč
    • •
  • 5 049 tis. Kč
    • •
  • MZ
Project

The role of CD36 gene in pathogenesis of Alzheimer´s disease (NV18-04-00455)

The project is focused on the role of CD36 gene in the pathogenesis between CD36 gene and Alzheimer’s disease (AD). CD36 is involved in the removal. CD36 gene will be analyzed for all polymorphisms/mutations by the...

Clinical neurology

  • 2018 - 2021
    • •
  • 11 992 tis. Kč
    • •
  • 11 992 tis. Kč
    • •
  • MZ
Project

Molecular mapping and positional cloning of genes that are responsible for clustering of cardiovascular risk factors (GA305/00/1646)

. However, the role of Cd36 in the pathogenesis of hypertension is unknown and at least oxide synthase (Nos3) and leptin gene (Lep), are linked to Cd36 on chromosome 4. Thus, it is possible that a gene linked to Cd36 such a...

EB - Genetika a molekulární biologie

  • 2000 - 2002
    • •
  • 2 919 tis. Kč
    • •
  • 2 505 tis. Kč
    • •
  • GA ČR
Project

Pathogenesis of cardiovascular risk factors cluster analyzed by transgenesis with Srebp1c transcription factor (NB6468)

cholesterol and reduction of fat mass. We found a mutation of Srebp1 in the SHR. We...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 5 033 tis. Kč
    • •
  • 3 454 tis. Kč
    • •
  • MZ
Project

Modulation of Fatty Acid Reesterification in Adipose Tissue by Lipid Mediators (LH14040)

portion of fatty acids is reesterified, how are fatty acid transporters (e.g. CD36 and adipose tissue with respect to fatty acid transporter CD36 and composition of dietary specialized methods of mass spectrometry, cells and mice w...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2014 - 2016
    • •
  • 1 910 tis. Kč
    • •
  • 1 910 tis. Kč
    • •
  • MŠMT
Project

Changes of lipid metabolism and composition during colorectal carcinogenesis - the effects of butyrate and polyunsaturated fatty acids (GAP301/11/1730)

proteins (FAT/CD36, caveolin-1), accumulation of cytoplasmic lipid droplets...

EB - Genetika a molekulární biologie

  • 2011 - 2013
    • •
  • 6 874 tis. Kč
    • •
  • 6 874 tis. Kč
    • •
  • GA ČR
Project

Metabolic flux analysis of carbohydrates and lipids in adipose tissue (LTAUSA17173)

. Multifunctional protein CD36 is also involved in fatty acid utilization via the interaction...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2017 - 2019
    • •
  • 2 284 tis. Kč
    • •
  • 2 284 tis. Kč
    • •
  • MŠMT
Project

New metabolic pathways of lipid trafficking (LUAUS24040)

of fatty acids during transcytosis in relation to the presence of the CD36 transporter. Signalling through lipokines 3.1 Define the signaling potential of FAHFA through the CD36......

Biochemistry and molecular biology

  • 2024 - 2027
    • •
  • 10 122 tis. Kč
    • •
  • 10 122 tis. Kč
    • •
  • MŠMT
Project

Using 13C and proton MR spectroscopy to study the role of fatty acid transport and accumulation in tissues in the pathogenesis of insulin resistance (GAP301/11/2418)

The metabolic syndrome represents a cluster of metabolic disorders that increase the risk of type 2 diabetes and cardiovascular disease. The key role is ascribed to dyslipidemia and associated ectopic lipid accumulation in non-adipose tissues such as...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2011 - 2014
    • •
  • 5 272 tis. Kč
    • •
  • 5 272 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 194