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18 (0,05s) •

Project

Genetics of adult-onset familial focal segmental glomerulosclerosis (FSGS) – implications for individualized therapy and successful kidney transplantation (NV19-06-00443)

Focal segmental glomerulosclerosis (FSGS) is a clinically and genetically heterogeneous entity that manifests mostly by proteinuria. FSGS is responsible for about 15 transplantation. FSGS may be of genetic etiology. More th...

Human genetics

  • 2019 - 2023
    • •
  • 13 856 tis. Kč
    • •
  • 12 179 tis. Kč
    • •
  • MZ
Project

Genetic factors influencing the progression of selected forms of nephrotic syndrome (NS9779)

and segmental glomerulosclerosis (FSGS), membranous glomerulonephritis (MGN) and IgA nephropathy (IGAN). In adult patients with MCD/FSGS the most frequent genetic abnormality with histologically proven diagnosis of MCD/FSGS

EB - Genetika a molekulární biologie

  • 2008 - 2011
    • •
  • 3 492 tis. Kč
    • •
  • 3 492 tis. Kč
    • •
  • MZ
Project

Gene polymorphisms and intrarenal expression of genes in Focal segmental glomerulosclerosis and their relation to progression of the disease (NR9523)

I: To observe a correlation among an intrarenal expression of genes for MCP-1, RANTES, TGFbeta1, HGF, BMP and VEGF, an infiltration of renal tissue by leukocytes, an ammount of proteinuria and the progression of FSGS. II: To investigate if t...

FE - Ostatní obory vnitřního lékařství

  • 2007 - 2010
    • •
  • 6 832 tis. Kč
    • •
  • 6 609 tis. Kč
    • •
  • MZ
Project

The significance of interleukins for diagnosis and treatment of patients with chronic glomerulonephritis. (IZ2228)

9F - 9

  • 1994 - 1996
    • •
  • 567 tis. Kč
    • •
  • 835 tis. Kč
    • •
  • MZ
Project

Use of interferon in the treatment of viral infections. (IZ2098)

9F - 9

  • 1994 - 1996
    • •
  • 560 tis. Kč
    • •
  • 810 tis. Kč
    • •
  • MZ
Project

The reinforcement of the inhibition mediated by GABA in the treatment of epilepsies. (IZ2210)

9F - 9

  • 1994 - 1995
    • •
  • 305 tis. Kč
    • •
  • 1 592 tis. Kč
    • •
  • MZ
Project

Oscillation and spectral theory of differential and difference systems (GC201/09/J009)

The aim of the project is to study qualitative properties of solutions of linear Hamiltonian differential systems and of symplectic difference systems. Attention will be focused to the following particular problems:1. Qualitative theory of linear Ham...

BA - Obecná matematika

  • 2009 - 2011
    • •
  • 759 tis. Kč
    • •
  • 759 tis. Kč
    • •
  • GA ČR
Project

Human spatial navigation functions in real space and their brain localization (GA309/09/1053)

The aim of the proposed project is the brain localization of several types of spatial navigation in a real space environment. The project will focus on the types of spatial navigation that are difficult to study in virtual environments and therefore ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2009 - 2011
    • •
  • 4 075 tis. Kč
    • •
  • 4 075 tis. Kč
    • •
  • GA ČR
Project

Changes of sensorimotor system organization and activation following botulinum toxin injection in cervical dystonia patients (NV16-30210A)

Patients suffering from cervical dystonia (CD) are very often notably limited in working and social activities. Botulinum toxin (BoNT-A) is currently considered to be the one of the most effective therapeutic options. However, the complete mechanism ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2019
    • •
  • 6 726 tis. Kč
    • •
  • 6 726 tis. Kč
    • •
  • MZ
Project

Stratification of patients with focal cortical dysplasia towards optimizing epilepsy surgery (NV19-04-00369)

Epilepsy surgery represents an established method to treat intractable focal epilepsy, in majority of patients caused by malformations of cortical development (MCD), specifically focal cortical dysplasia (FCD). Histopathological, neuroimaging, electr...

Clinical neurology

  • 2019 - 2022
    • •
  • 16 321 tis. Kč
    • •
  • 16 321 tis. Kč
    • •
  • MZ
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