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3 007 (0,098s)

Project

Fc receptors on immune cells and clinical manifestation in patients with primary immunodeficiency (NI7138)

The relation of membrane structures, particularly Fc gamma receptors to the severity of clinical manifestation and to the efficacy of gammaglobulin therapy in patients with primary immunodeficiency will be analysed in the study. A p...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2002 - 2004
  • 2 881 tis. Kč
  • 2 841 tis. Kč
  • MZ
Project

Monitoring of protein network dynamics during sperm-egg membrane interaction (GA18-11275S)

this effort, the egg receptor for sperm primary fusion protein Izumo1 has still not been found. This project aims to investigate the novel physiological egg ligand Fc receptor-like for Izumo1 and confirm its relev...

Reproductive biology (medical aspects to be 3)

  • 2018 - 2020
  • 7 875 tis. Kč
  • 7 875 tis. Kč
  • GA ČR
Project

Screening of mutations and polymorphisms in neonatal Fc receptor gene in patients with primary disorders of antibody production (NR9192)

The aim of our project is to completely map mutation and/or polymorphism spectrum in the FcRn gene in healthy subjects and in patients with primary disorders of antibody production. It will be determined whether and how a sequence variability in the ...

EB - Genetika a molekulární biologie

  • 2007 - 2009
  • 3 526 tis. Kč
  • 3 476 tis. Kč
  • MZ
Project

Center of molecular and cellular immunology (LN00A026)

The aim of the project is to elucidate molecular basis of key mechanisms regulating immune reactions under normal and pathological conditions, by means of basic research of lymphocyte antigen-specific receptors, receptors of certain...

EC - Imunologie

  • 2000 - 2004
  • 115 858 tis. Kč
  • 76 500 tis. Kč
  • MŠMT
Project

DNA Condensation Monte-Carlo Simulations, Light Scattering, Fluorescence Correlation Spectroscopy in vitro and in vivo. (IAA400400621)

fluorescence studies and time-resolved FCS, we would like to get deeper insightThe DNA condensation is crucial for transport of DNA inside living cells, i.e. for non-viral gene therapy. Fluorescence correlation spectroscopy (FC...

CF - Fyzikální chemie a teoretická chemie

  • 2006 - 2010
  • 6 738 tis. Kč
  • 6 738 tis. Kč
  • AV ČR
Project

Toll-like receptors in prostate carcinogenesis and therapy resistance (NV17-28518A)

. In the present translational project we will examine the role of toll-like receptors in regulation of cellular events associated with resistance. Toll-like receptors carcinogenesis has also been described. In thi...

FD - Onkologie a hematologie

  • 2017 - 2021
  • 14 546 tis. Kč
  • 14 531 tis. Kč
  • MZ
Project

Organisation of FC/DFC units in mammalian nucleoli. (GA19-21715S)

centers (FC), dense fibrillary components (DFC) and granular component (GC). Each FC with surrounding DFC constitutes a FC/DFC unit. These units play key role in the cell. But dynamic organization of the FC/DFC un...

Cell biology

  • 2019 - 2022
  • 6 741 tis. Kč
  • 6 708 tis. Kč
  • GA ČR
Project

*Milling working place FC. (FI-IM/123)

*Development, design, manufaturing and verification of the FC milling working place. Outcome of this project will be used for introducing of the new ŠMT product on the machine tool market. The technological working place FC is consi...

JQ - Strojní zařízení a nástroje

  • 2004 - 2007
  • 110 tis. Kč
  • 25 tis. Kč
  • MPO
Project

Safety traffic barrier of road tunnels – SOFT STOP (TA04031111)

) and Feramat Cybernetics (FC), in increased safety of road tunnels and in decreased to increasing collaboration among TC, FC and University of West Bohemia (UWB). Specific design. FC, ZCU. 12/2014. 3. Barrier support des...

JO - Pozemní dopravní systémy a zařízení

  • 2014 - 2017
  • 26 611 tis. Kč
  • 16 668 tis. Kč
  • TA ČR
Project

Molecular mechanisms of signalling through immunoreceptors (GA204/99/0367)

Based on previous projects of our laboratory, molecular details of early phases of signalling processes used by immunoreceptors (TCR, BCR, Fc-receptors) will be examined. The main aims will be (1) To determine by means of novel elec...

CE - Biochemie

  • 1999 - 2001
  • 1 359 tis. Kč
  • 1 359 tis. Kč
  • GA ČR
  • 1 - 10 out of 3 007