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10 541 (0,083s) •

Project

Exploiting the regenerative potential of the stable fibroblast growth factor 2 in cosmeceutics (EG20_321/0023865)

cosmetic product with a bioactive substance, which will be stable fibroblast growth factor 2 (FGF2). The developed product will be able to be included in the segment containing the active substance in the...

Chemical process engineering

  • 2021 - 2023
    • •
  • 6 715 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MPO
Project

FGF2-STAB as a key component for the cell-cultured meat media (TP03020019)

1) To receive feedback on the FGF2-STAB technology to be used specifically for the cell-cultured meat industry 2) To design FGF2-STAB with parameters meeting cell-based meat industry regulatory standards 3) To actively bu...

Industrial biotechnology

  • 2021 - 2022
    • •
  • 938 tis. Kč
    • •
  • 516 tis. Kč
    • •
  • TA ČR
Project

Exploring the structure function relationship of membrane-pore-forming FGF2 oligomers - a single molecule approach (GC20-01401J)

Fibroblast Growth Factor 2 (FGF2) is a cell survival factor mediating tumor, FGF2 is secreted from cells by direct protein translocation across the plasma membrane. Several lines of evide...

Biophysics

  • 2020 - 2022
    • •
  • 4 953 tis. Kč
    • •
  • 4 616 tis. Kč
    • •
  • GA ČR
Project

Exploring the structure function relationship of membrane-pore-forming FGF2 oligomers - a single molecule approach (GC14-03141J)

Fibroblast Growth Factor 2 (FGF2) has numerous biological activities, which are exerted when FGF2 is secreted into the extracellular space. It however lacks a signal). Only little is known about t...

BO - Biofyzika

  • 2014 - 2016
    • •
  • 3 933 tis. Kč
    • •
  • 3 933 tis. Kč
    • •
  • GA ČR
Project

The role of FGF2 secretion in the physiology of human pluripotent stem cells (GA15-23033S)

. For their self-renewal, hPSC require active signaling provided by the fibroblast growth factor receptors (FGFR). When the FGFR signaling is not active, hPSC lose their pluripotency and increase apoptosis. Previously we sh...

EB - Genetika a molekulární biologie

  • 2015 - 2017
    • •
  • 5 752 tis. Kč
    • •
  • 5 752 tis. Kč
    • •
  • GA ČR
Project

Fibroblast growth factor signaling pathways in human embryonic stem cells (GA305/05/0434)

exists regarding growth factor signaling in this particular cell type. It has been demonstrated that hES cells require exogenous basic fibroblast growth factor (FGF-2) to proliferate in an undiff...

ED - Fyziologie

  • 2005 - 2007
    • •
  • 4 602 tis. Kč
    • •
  • 4 602 tis. Kč
    • •
  • GA ČR
Project

Nanodiamonds as selective protein traps to regulate disorders caused by aberrant FGF2 signaling (GA23-04876S)

Nanodiamonds (NDs) exhibit highly efficient depletion of FGFs belonging to the paracrine FGF subfamily. We have previously shown their regulation effect on FGF ligands in cell and organ cultures after their treatment with ectopic FGF2. Here,...

Urology and nephrology

  • 2023 - 2025
    • •
  • 13 790 tis. Kč
    • •
  • 13 418 tis. Kč
    • •
  • GA ČR
Project

Optimization of nanostructured dermal substitutes in animal model (NV17-29874A)

(dermal substitute) doped with hyperstable fibroblast growth factor FGF2 and covered facilitates ingrowth of native fibroblasts and blood vessels while nanoporous mucoadhesive, biomechanically, in-vitro o...

FJ - Chirurgie včetně transplantologie

  • 2017 - 2020
    • •
  • 11 634 tis. Kč
    • •
  • 11 634 tis. Kč
    • •
  • MZ
Project

Inborn skeletal disorders caused by mutations in fibroblast growth factor receptors/FGFR/ (NM25)

Mutations of the genes coding for fibroblast growth factor receptors(FGFR)and their phenotypic expression will be studied in patients with selected inborn skeletal disorders in order to improve diagnostics and classificatio...

EB - Genetika a molekulární biologie

  • 1998 - 2000
    • •
  • 2 185 tis. Kč
    • •
  • 2 185 tis. Kč
    • •
  • MZ
Project

Production of stable fibroblast growth factors for research, therapeutic and cosmetic applications (TH02010219)

The aim of the project is to remove low stability of fibroblast growth factors (FGFs) that prevents their practical use. FGFs are proteins that promote cell proliferation and differentiation in the human body and, thus, fac...

EI - Biotechnologie a bionika

  • 2017 - 2020
    • •
  • 20 364 tis. Kč
    • •
  • 12 186 tis. Kč
    • •
  • TA ČR
  • 1 - 10 out of 10 541