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5 (0,163s)

Project

Markers of transplantation tolerance after renal transplantation (NS10517)

Under this project, 75 renal graft recipients at risk of developing rejection will be monitored prospectively (at predefined intervals) for the presence of naturally occurring (CD4+CD25+FoxP3+) as well as the degree of expression of mRNA of ...

EB - Genetika a molekulární biologie

  • 2009 - 2011
  • 4 797 tis. Kč
  • 4 797 tis. Kč
  • MZ
Project

Predictive immunological markers in patients with hepatitis C viral infection (NT14072)

The following markers will be examined in the blood of adult patients with chronic hepatitis C (HC), genotype 1b in Prague and Hradec Králove: 1) Expression of activation markers CD38 a HLA-DR on the cytotoxic T lymphocytes (CTLs) presents the inform...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2013 - 2015
  • 7 567 tis. Kč
  • 7 567 tis. Kč
  • MZ
Project

Novel treatment of genetically determined metabolic disease, type 1 diabetes, using an immunotherapeutical approach. (2B08066)

The aim of the proposed project is a characterization of genetical profile of patients with type 1 diabetes mellitus (T1D) and induction of specific immune tolerance. Immunotherapeutical approaches could achieve complete cure of T1D or reverse unfavo...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2008 - 2011
  • 44 736 tis. Kč
  • 38 751 tis. Kč
  • MŠMT
Project

The impact of DPP-4 inhibitor therapy on immunity functions in patients with type 2 diabetes mellitus (NT12407)

, together with the relevant enzymatic activity, Treg (CD4+CD25+CD127-/FoxP3+) and CD86...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2011 - 2015
  • 6 646 tis. Kč
  • 6 630 tis. Kč
  • MZ
Project

Monocyte subpopulations in kidney transplantation and regulatory mechanisms of human macrophage differentiation (NS10524)

schedule. The determination of T regulatory cells (CD4+CD25+Foxp3+) and gene...

EC - Imunologie

  • 2009 - 2011
  • 4 206 tis. Kč
  • 4 206 tis. Kč
  • MZ
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