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19 (0,102s) •

Project

Proteome analysis of extracytoplasmic stress response in Francisella tularensis strain with different virulence (OC 151)

Proteome analysis of extracytoplasmatic stress response in cell membrane of intrcellular pathogen Francisella tularensis...

EE - Mikrobiologie, virologie

  • 2007 - 2010
    • •
  • 23 405 tis. Kč
    • •
  • 1 905 tis. Kč
    • •
  • MŠMT
Project

Development of new prophylactic tools against Francisella tularensis infection (OVUOFVZ200808)

Identification of new candidate molecules of protein origin suitable for the construction of better defined live or subunit vaccines and elucidation of the process of antigen presentation of tularemic peptides as a key event for the development of ne...

EC - Imunologie

  • 2008 - 2011
    • •
  • 9 384 tis. Kč
    • •
  • 6 420 tis. Kč
    • •
  • MO
Project

Biological detection of microbial agens Francisella tularensis (MO66021299105)

Identification of specific sequences of proteine components of microorganisms duitable as a bio-recognitionpart of biosensors. Creation of gene-proteine database of microorganisms.......

EE - Mikrobiologie, virologie

  • 1999 - 2001
    • •
  • 1 325 tis. Kč
    • •
  • 1 325 tis. Kč
    • •
  • MO
Project

Virulence factors of intracellular pathogen Francisella tularensis classified as cathegory A biological warfare agents (OPUOFVZ200602)

The research aimed at detection of possible factors of virulence Francisella tularensis led to the finding of pathogenicity island involving genes critical potential factors of virulence of intracellular pathogen Francisella tularen...

EC - Imunologie

  • 2006 - 2008
    • •
  • 10 384 tis. Kč
    • •
  • 5 734 tis. Kč
    • •
  • MO
Project

Local immune response of host against transdermal infection with intracellular bacterial pathogen Francisella tularensis (NI4700)

LD50 of transdermal infection with Francisella tularensis is of several logs higher than of other ways of infection. The reason is unclear. Unknown local immune factors seem to participate. Transdermal infection is natural way for spreading ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1998 - 2000
    • •
  • 3 371 tis. Kč
    • •
  • 2 509 tis. Kč
    • •
  • MZ
Project

Mechanisms of innate resistance to infection with intracellular bacterial pathogens BCg/Lsh/Ity/ (Nramp1) gene and Francisella tularensis infection (GA310/99/1185)

Mechanisms of innate resistance to infection with intracellular bacterial pathogens:Bcg/Lsh/Ity (Nramp1) gene and Francisella tularensis infection. Innate resistance to infection with intracellular bacterial pathogens is substantionally infl...

EC - Imunologie

  • 1999 - 2000
    • •
  • 1 726 tis. Kč
    • •
  • 1 726 tis. Kč
    • •
  • GA ČR
Project

Proteomic analysis Francisella tularensis LVS cultivated intracellular in vitro and in vivo, identification of potential virulence factors (GP310/06/P266)

Infections caused by intracellular bacteria represent a real threat due to the insufficient understanding of molecular mechanisms of pathogeneses. For example Francisella tularensis is characterized by high virulence, easy aerosol transmissi...

EE - Mikrobiologie, virologie

  • 2006 - 2008
    • •
  • 1 180 tis. Kč
    • •
  • 1 180 tis. Kč
    • •
  • GA ČR
Project

Differential proteome analysis of bacterial Francisella tularensis glyco- and phospho- proteins (ME08105)

of Francisella tularensis proteins, their post-translational modifications as glycosylation...

CB - Analytická chemie, separace

  • 2008 - 2010
    • •
  • 2 802 tis. Kč
    • •
  • 2 082 tis. Kč
    • •
  • MŠMT
Project

Study of B-cell interaction with intracellular pathogen Francisella tularensis. (GA310/07/0226)

Originally, it was thought that immunity against Francisella tularensis is predominately cell-mediated. However, recent studies clearly show both contributions of specific antibodies in the host defense and the role of B cells in non-specifi...

EC - Imunologie

  • 2007 - 2009
    • •
  • 2 375 tis. Kč
    • •
  • 2 375 tis. Kč
    • •
  • GA ČR
Project

The role of B cells during natural and adaptive phase of immune response against Francisella tularensis infection in mice (GAP302/11/1631)

Tularemia is a zoonotic infection with high infectivity and high morbidity. The etiological agent of tularemia is Francisella tularensis, an intracellular pathogen on all major lists of potential bioterroristic agents. The live vaccine strai...

EC - Imunologie

  • 2011 - 2014
    • •
  • 4 325 tis. Kč
    • •
  • 4 325 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 19