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458 (0,171s) •

Project

Relations between topological spaces and their topological groups of G-valued continuous functions for a given topological group G (GPP201/12/P724)

Let G be a topological group. Given a topological space X, we denote by Cp(X, G) the group of all continuous functions from X to G endowed with the topology of pointwise convergence. Spaces X and Y are called G-equ...

BA - Obecná matematika

  • 2012 - 2014
    • •
  • 1 188 tis. Kč
    • •
  • 1 188 tis. Kč
    • •
  • GA ČR
Project

Role of receptor/G protein preassembly in G protein signaling (GJ20-09628Y)

G proteins and G protein-coupled receptors (GPCRs) play a key role in cellular signal transduction. An important aspect of G protein signaling, the role of which and G protein molecules. Particularly, it is not kno...

Biophysics

  • 2020 - 2022
    • •
  • 4 908 tis. Kč
    • •
  • 4 875 tis. Kč
    • •
  • GA ČR
Project

Structure characterization of g-RNA from Trypanosoma brucei (1K04011)

In this grant application we propose structural studies of g-RNA molecules spectroscopy will be used to charakterize secondary and terciary structures of several g structural motive common to all g-RNAs, which is expected t...

BO - Biofyzika

  • 2004 - 2006
    • •
  • 2 507 tis. Kč
    • •
  • 1 843 tis. Kč
    • •
  • MŠMT
Project

Enhancement of G-CSF action by adenosine signalling testing of its potential clinical use in murine models (GA306/99/0027)

effects of granulocyte colony-stimulating factor (G-CSF) and drugs elevating with respect to the clinical use of G-CSF. Interactions of G-CSF with dipyridamole and AMP will be studied in the following two experimental situ...

ED - Fyziologie

  • 1999 - 2001
    • •
  • 2 397 tis. Kč
    • •
  • 1 821 tis. Kč
    • •
  • GA ČR
Project

Population genetics and ecology of some rare or endangered species of family Gentianaceae (IAB6141901)

The project is focused upon the population biology of Gentiana species (G. cruciata, G. pannonica and G. pneumananthe) and Gentianella species (G. amarella, G. campestris ssp. baltica, G. obtusifo...

EF - Botanika

  • 1999 - 2001
    • •
  • 942 tis. Kč
    • •
  • 712 tis. Kč
    • •
  • AV ČR
Project

Heterotrimeric G-protein signaling and its role in regulation of cell proliferation and morphogenesis in plants (LD15149)

The aim of the project is to better understand the role of heterotrimeric G activity of G-protein complex on sugar metabolism (realization till 12/2015) 2) To describe expression of genes encoding components of G-protein si...

ED - Fyziologie

  • 2015 - 2017
    • •
  • 1 039 tis. Kč
    • •
  • 1 039 tis. Kč
    • •
  • MŠMT
Project

New kits for diagnosis of impaired cytokine, growth factors and HLA-G antigens (OE119)

antibodies again, st HLA-G and HLA-E antigens and construction ELISA kit for the detection of serum HLA-G proteins., ,...

EI - Biotechnologie a bionika

  • 2002 - 2004
    • •
  • 8 640 tis. Kč
    • •
  • 4 048 tis. Kč
    • •
  • MŠMT
Project

Visualizing GPCR-G-protein-beta-arrestin supercomplexes in living cells using two-photon polarization microscopy (LTAIN19167)

To observe the presence and intracellular localization of GPCR-G-protein-beta-arrestin supercomplexes in order to determine their physiological role.......

Biophysics

  • 2020 - 2022
    • •
  • 4 754 tis. Kč
    • •
  • 4 754 tis. Kč
    • •
  • MŠMT
Project

Templated synthesis and product characterization focused at development of potent and selective ligands of c-myc G-quadruplex (GA17-04393S)

Rational design of novel ligands of c-myc G-quadruplex is inherently difficult this shortcoming and identify novel binders of c-myc G-quadruplex we propose to explore in situ. Specifically, c-myc G-quadruplex will be explor...

CC - Organická chemie

  • 2017 - 2018
    • •
  • 4 135 tis. Kč
    • •
  • 2 994 tis. Kč
    • •
  • GA ČR
Project

Influence of allosteric modulators on specificity of coupling with G-proteins and desensitization of muscarinic receptors (GA305/05/0452)

In spite of preferential coupling of muscarinic receptors to distinct classes of heterotrimeric G proteins, they can also interact with other G proteins. Allosteric alter receptor preference for G proteins. They might also ...

ED - Fyziologie

  • 2005 - 2007
    • •
  • 4 992 tis. Kč
    • •
  • 4 992 tis. Kč
    • •
  • GA ČR
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