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514 (0,111s) •

Project

Enhancement of G-CSF action by adenosine signalling testing of its potential clinical use in murine models (GA306/99/0027)

effects of granulocyte colony-stimulating factor (G-CSF) and drugs elevating with respect to the clinical use of G-CSF. Interactions of G-CSF with dipyridamole and AMP will be studied in the foll...

ED - Fyziologie

  • 1999 - 2001
    • •
  • 2 397 tis. Kč
    • •
  • 1 821 tis. Kč
    • •
  • GA ČR
Project

Possibilities of the enhancement of G-CSF efficacy under conditions of radiation-induced myelosuppression by the extracellular adenosine receptor action (GA306/96/1721)

of granolocyte colony-stimulating factor (G-CSF). The efficacy of the combined action of mechanism of extracellular adenosine signalling and of the G-CSF willbeevaluated under of the project is to contribute to t ...

BO - Biofyzika

  • 1996 - 1998
    • •
  • 2 017 tis. Kč
    • •
  • 1 423 tis. Kč
    • •
  • GA ČR
Project

The role of signalling through adenosine receptors and its interaction with G-CSF in regulation of haematopoiesis (GP305/03/D050)

in the frame of the garant's project, and investigation of its interaction with G-CSF alone or in combination with G-CSF will be performed. Besides the nonspecific of selected haematopoietic growth factors, namely...

FR - Farmakologie a lékárnická chemie

  • 2003 - 2006
    • •
  • 677 tis. Kč
    • •
  • 677 tis. Kč
    • •
  • GA ČR
Project

The Hight Chemotherapy Supported with Mobilised Stem Cells in the Whole Blood. (IZ3679)

9F - 9

  • 1996 - 1996
    • •
  • 0 tis. Kč
    • •
  • 178 tis. Kč
    • •
  • MZ
Project

ROLE OF CYTOKINE PRIMING IN AZACITIDINE-MEDIATED LEUKEMIA STEM CELL DIFFERENTIATION IN THERAPY OF PROGRESSING MYELODYSPLASIA (GA18-01687S)

-colony stimulating factor (G-CSF) added prior DNMTi improved AZA-mediated blood cell differentiation in vitro. We now initiate academic study of G-CSF prior AZA (GA-MDS-2013......

Oncology

  • 2018 - 2020
    • •
  • 10 226 tis. Kč
    • •
  • 10 082 tis. Kč
    • •
  • GA ČR
Project

Therapeutic Vasculogenesis In Patients With Peripheral Artery Disease (NR8047)

Sixty patients with critical peripheral artery disease of the leg without further revascularization possibilities will be randomized into the three arm study. In the first arm, standard treatment with prostaglandin for four weeks will be given. In th...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2004 - 2006
    • •
  • 4 649 tis. Kč
    • •
  • 4 122 tis. Kč
    • •
  • MZ
Project

Reprogramming the fate of hematopoietic cells in cyprinid fish (GA24-10486S)

that the committed erythroid cells can be reprogrammed into myeloid cells by G-CSF only...

Cell biology

  • 2024 - 2026
    • •
  • 9 942 tis. Kč
    • •
  • 8 964 tis. Kč
    • •
  • GA ČR
Project

The role of apoptosis in pathogenesis,prognosis and treatment of myelodysplastic syndrome (NK5937)

Detection of the rate of apoptosis in native cell subpopulations and in cultured cells obtained ftom patiens with different stages of myelodysplastic syndrome. Investigation of the role the rate of apoptosis in prognosis,prediction of leulemic proges...

FD - Onkologie a hematologie

  • 2000 - 2002
    • •
  • 2 851 tis. Kč
    • •
  • 2 744 tis. Kč
    • •
  • MZ
Project

Differential diagnostics of inflammatory and autoimmune CNS diseases by means of CSF protein fractions evaluation. (NF6460)

The project follows preceding works of our working group and assumes the evaluation of biological significance of CSF protein fractions by means of analytical methods, by monitoring CSF cytological picture and employment of the spec...

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
    • •
  • 1 069 tis. Kč
    • •
  • 990 tis. Kč
    • •
  • MZ
Project

Investigation of cerebrospinal fluid in diagnostics of inborn errors of neurotransmitter metabolism and mitochondrial diseases. (NS10561)

and/or their metabolites in CSF. Central nervous system belongs to the most affected organ also in mitochodriopathies and CSF investigations are important in their diagnostic process. The aimof and their metabolites in CSF...

FG - Pediatrie

  • 2009 - 2011
    • •
  • 4 599 tis. Kč
    • •
  • 4 599 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 514