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2 779 (0,092s) •

Project

Genetic study of alcohol dependence detection of the association between candidate gene polymorphisms and alcoholism. (NF5991)

The project is concerned with the genetic disposition to alcohol dependence. The molecular biological methods and association analysis using the candidate gene polymorphism in the groups of 400 alcoholics and 400 controls subjects w...

FL - Psychiatrie, sexuologie

  • 2000 - 2002
    • •
  • 2 009 tis. Kč
    • •
  • 2 006 tis. Kč
    • •
  • MZ
Project

Genetic aspects of the cisplatin induced ototoxicity - the prospective association study (NS10101)

will be obtained from that probands and DNA will be isolated in which genetic polymorphisms will be assessed. Results of clinical and genetic assessments will be statistically compared to find a significant associations be...

FF - ORL, oftalmologie, stomatologie

  • 2008 - 2011
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  • 2 470 tis. Kč
    • •
  • 2 470 tis. Kč
    • •
  • MZ
Project

Genetic predisposition to osteoporosis. (NB7380)

An analysis of the association between common polymorphisms in the transforming growth factor beta -1, plasminogen-activator inhibitor and collagen type 1 genes and osteoporosis.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
    • •
  • 2 574 tis. Kč
    • •
  • 2 573 tis. Kč
    • •
  • MZ
Project

Genetic factors influencing the development of celiac disease in Type 1 diabetic children. (NB7413)

Proposed study will investigate the contribution of susceptible genotypes (HLA-DQ, CTLA4 polymorphism, cytokine genes polymorphism) for the high frequency of celiac disease in children with Type 1 diabetes.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
    • •
  • 1 815 tis. Kč
    • •
  • 1 808 tis. Kč
    • •
  • MZ
Project

Genetic Polymorphisms in Connection with Clinical Forms of Crohn´s Disease and it´s Response to Treatment (NR9342)

Detection of chosen genetic polymorphism by the Crohn disease suffers and their leading kinsmen. Possible dependence of some polymorphism incidence investigation and the form of Crohn disease clinical presentment, as well a...

FP - Ostatní lékařské obory

  • 2007 - 2009
    • •
  • 1 647 tis. Kč
    • •
  • 1 647 tis. Kč
    • •
  • MZ
Project

Case-control study on colorectal carcinoma genetic profiling of xenobiotic metabolising and DNA repair enzymes (GA310/05/2626)

by genetic polymorphisms in a number of biotransformation (XME) and DNA repair genes individual genetic background (evaluation of polymorphisms in both DNA repair and XME genes) and expression levels in peripheral...

FD - Onkologie a hematologie

  • 2005 - 2007
    • •
  • 4 780 tis. Kč
    • •
  • 4 780 tis. Kč
    • •
  • GA ČR
Project

Conformational polymorphism of DNA molecules containing trinucleotide repeats associated with genetic diseases (GA204/01/0561)

Conformational polymorphism is a probable reason of microsatellite expansions in genomes. The expansions lead to serious genetic diseases in some cases. On the basis of our previous experience with model DNA molecules, we suggest to...

EB - Genetika a molekulární biologie

  • 2001 - 2003
    • •
  • 4 566 tis. Kč
    • •
  • 2 516 tis. Kč
    • •
  • GA ČR
Project

Molecular pathology and genetic diagnostics of Parkinson's disease (NT11331)

The grant project is focused on research of genetics of Parkinson's disease (PD analysis of the prevalence and types of mutations/polymorphisms in genes associated-onset PD (= high proportion of genetic cause) will be perfo...

FH - Neurologie, neurochirurgie, neurovědy

  • 2010 - 2015
    • •
  • 9 704 tis. Kč
    • •
  • 9 704 tis. Kč
    • •
  • MZ
Project

Sepsis Risk Evaluation in Children by Gene Polymorphism Study (NR8046)

The aim of this project is to introduce the genetic determination of sepsis in children based on polymorphism studies of certain genes. The results can reveal gene variant combinations predisposing to severe sepsis.......

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 3 411 tis. Kč
    • •
  • 2 963 tis. Kč
    • •
  • MZ
Project

Genetic diversity and its conservation in selected horse populations in the Czech Republic (QH92277)

The aim of the project is to use standard and new molecular markers of genetic diversity (microsatellites and single nucleotide polymorphisms, respectively) to characterize and to monitor the extent of genetic diversity of ...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2009 - 2011
    • •
  • 3 563 tis. Kč
    • •
  • 3 155 tis. Kč
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  • MZe
  • 1 - 10 out of 2 779