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8 (0,127s) •

Project

Glycomic and proteomic analysis of the molecular mechanisms of elimination of clinically relevant tumors by killer cells of the immune system (GA303/09/0477)

The aim of the project will be to use the modern technologies of contemporary proteomics, glycomics, and array technologies to dissect the molecular mechanisms behind the recognition and elimination of tumor cells by the killer cells of the ...

CE - Biochemie

  • 2009 - 2013
    • •
  • 4 259 tis. Kč
    • •
  • 4 259 tis. Kč
    • •
  • GA ČR
Project

Glycomic analysis of head and neck cancer - determination of prognostic relevance (NR9049)

of the results of glycomic analysis to the survival parameters will be defined. The most...

FD - Onkologie a hematologie

  • 2006 - 2008
    • •
  • 2 657 tis. Kč
    • •
  • 2 657 tis. Kč
    • •
  • MZ
Project

Fluorinated carbohydrates A valuable tool to study glycan-protein interactions and remodel cell-surface glycome (LTC20052)

for manipulation of cell-surface glycome by metabolic inhibition; 3b) Determination of how the cell-surface glycome has been altered after treatment with compounds identified......

Organic chemistry

  • 2020 - 2023
    • •
  • 4 119 tis. Kč
    • •
  • 4 119 tis. Kč
    • •
  • MŠMT
Project

Glycobiological investigations pertaining to biomolecular differentiation of mammary carcinomas (GA16-04496S)

. In this project, we will measure aberrant glycosylation in tumors. Glycomic and glycoproteomic...

FD - Onkologie a hematologie

  • 2016 - 2020
    • •
  • 3 512 tis. Kč
    • •
  • 3 005 tis. Kč
    • •
  • GA ČR
Project

Towards a new era for the identification and characterisation of inborn errors of glycosylation (8F19002)

1.Combine omics approaches to solve the most elusive unsolved CDG cases; 2.Develop new ‘omics’ biomarkers for the detection, elucidation and prognosis of the disease; 3.Promote research into the pathophysiology of the disease; 4.Exploit new hypothese...

Social biomedical sciences (includes family planning, sexual health, psycho-oncology, political and social effects of biomedical research)

  • 2019 - 2022
    • •
  • 3 843 tis. Kč
    • •
  • 3 843 tis. Kč
    • •
  • MŠMT
Project

Influence of glycosylation on haptoglobin structure in patients with liver diseases. (LH13051)

Monitoring changes in haptoglobin three dimensional structure under the influence of altered glycosylation in patients with hepatocellular carcinoma and cirrhosis. Developing and optimizing methods for chemical cross-linking and H/D exchange. Mapping...

CE - Biochemie

  • 2013 - 2015
    • •
  • 1 575 tis. Kč
    • •
  • 1 575 tis. Kč
    • •
  • MŠMT
Project

Systems biology of Mycobacterium tuberculosis (7E11070)

genomics, lipidomics, glycomics under different environmental perturbations both...

EE - Mikrobiologie, virologie

  • 2011 - 2014
    • •
  • 3 498 tis. Kč
    • •
  • 3 498 tis. Kč
    • •
  • MŠMT
Project

The use of surface glycosylation in the immune recognition and elimination of tumors (GA204/06/0771)

malignant phenotypes and sensitivity for killer lymphocytes using glycomic approaches...

EB - Genetika a molekulární biologie

  • 2006 - 2008
    • •
  • 2 940 tis. Kč
    • •
  • 2 940 tis. Kč
    • •
  • GA ČR
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