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Projects

12 projects (0,165s) •

Project

Molecular epidemiology of hepatitis B virus sequencing analysis of the HBV genom as an epidemiological tool (NI6796)

Introduction of sequence analysis of PCR products of HBV isolates. Obtaining principle data about genom variability of HBV DNA isolates and geographic distribution of genotypes and mutants with clinical or epidemiological importance...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2001 - 2003
    • •
  • 3 679 tis. Kč
    • •
  • 1 556 tis. Kč
    • •
  • MZ
Project

HBV DNA Quantification and Determibation of HCV Serotype Extension of Selection Criteria in Patients with Chron.VHB,VHC Indicated for Interferon Therapy. (IZ3692)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1996 - 1998
    • •
  • 2 079 tis. Kč
    • •
  • 2 079 tis. Kč
    • •
  • MZ
Project

Sensing of hepatitis B virus-infected hepatocytes by plasmacytoid dendritic cells (GA17-15422S)

(IFN) alpha in human organism, in pathogenesis of hepatitis B virus (HBV) infection-localized covalently closed circular HBV DNA (cccDNA), a major obstacle of chronic functions of pDCs including secretion of IFN-alpha are skewed by...

EE - Mikrobiologie, virologie

  • 2017 - 2021
    • •
  • 7 608 tis. Kč
    • •
  • 6 891 tis. Kč
    • •
  • GA ČR
Project

Identification of novel antiviral targets in the nucleus of hepatitis B virus infected cells (GN24-11554O)

Chronic hepatitis B virus (HBV) infection is a major public health problem affecting approximately 250 million people worldwide. HBV genome forms covalently closed validated in HBV infection models. Collectively, high-throu...

Virology

  • 2024 - 2027
    • •
  • 5 273 tis. Kč
    • •
  • 5 273 tis. Kč
    • •
  • GA ČR
Project

*Research of the technology for sensitive and quantitative detection of human pathogens - viruses HCV and HBV - and the optimization of appropriate diagnostic process (FI-IM5/042)

*The aim of the project is the research and optimization of technology for detection of two pathogens HCV and HBV by means of polymerase chain reaction (PCR). These viruses cause hepatitis, which is one of the most serious human disease with...

FS - Lékařská zařízení, přístroje a vybavení

  • 2008 - 2010
    • •
  • 18 877 tis. Kč
    • •
  • 8 810 tis. Kč
    • •
  • MPO
Project

Immunomodulation in treatment of patients with chronic renal failure during anti HBV vaccination. (IZ2730)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1995 - 1998
    • •
  • 1 402 tis. Kč
    • •
  • 1 402 tis. Kč
    • •
  • MZ
Project

Hepatitis G virus (HGV,GBV-C) among blood donors and parenteral transmission high risk groups (NI4515)

Evaluation of methods for the HGV detection. Estimation of HGV prevalence among high risk groups: multitransfused patients blood donors and patients with viral hepatitis nonA-E. Studying of freqency of coinfection with HCV an HBV.......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1998 - 2000
    • •
  • 2 360 tis. Kč
    • •
  • 1 932 tis. Kč
    • •
  • MZ
Project

Embedding Antiviral Nanoparticles in Water and/or Air for Cleaning the Environment (LTAIZ19017)

The objectives of this proposal are: 1) to extend the application of the Ag-MUS and Au-MUS to other viral airborne infections (e.g. coxsackie virus, reovirus, adenovirus), water-borne infections (e.g. norovirus, rotavirus) and blood- and body fluid-b...

Virology

  • 2019 - 2022
    • •
  • 4 679 tis. Kč
    • •
  • 3 626 tis. Kč
    • •
  • MŠMT
Project

New Antivirals and Antineoplastics (1M0508)

The aim of the project is to design, synthesize and study novel drug candidates for treatment of viral diseases and neoplasia, compounds active against drug resistent HIV and HBV mutants, poxviruses and RNA viruses.To study new analogs of ac...

CC - Organická chemie

  • 2005 - 2011
    • •
  • 316 074 tis. Kč
    • •
  • 268 113 tis. Kč
    • •
  • MŠMT
Project

Novel antivirals and antineoplastics (1QS400550501)

The aim of this project is to develop novel antivirals and/or cytostatics based on nucleoside, nucleotide and nucleobase structure, to determine their transport characteristics, metabolism and mechanism of action, under the conditions acceptable for ...

CC - Organická chemie

  • 2005 - 2009
    • •
  • 20 500 tis. Kč
    • •
  • 20 500 tis. Kč
    • •
  • AV ČR
  • 1 - 10 out of 12