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Projects

19 projects (0,074s) •

Project

Molecular epidemiology of hepatitis C virus in the Czech Republic (NR9044)

Set up of sequence analysis of PCR fragments of HCV genome isolates. Obtaining of basic data about variability of HCV in infected persons from low-risk group of blood sequences of HCV isolates from Czech Republic. Mapping o...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2006 - 2008
    • •
  • 3 265 tis. Kč
    • •
  • 3 028 tis. Kč
    • •
  • MZ
Project

High-affinity protein binders of hepatitis C virus broadly-neutralizing antibodies as a base for preventative vaccine (NU23-05-00203)

More than 130 million people worldwide are infected with hepatitis C virus (HCV of infected individuals and thus the risk of developing chronic HCV infection-associated toward controlling HCV infection. Surface HCV...

Immunology

  • 2023 - 2026
    • •
  • 13 783 tis. Kč
    • •
  • 13 783 tis. Kč
    • •
  • MZ
Project

HBV DNA Quantification and Determibation of HCV Serotype Extension of Selection Criteria in Patients with Chron.VHB,VHC Indicated for Interferon Therapy. (IZ3692)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1996 - 1998
    • •
  • 2 079 tis. Kč
    • •
  • 2 079 tis. Kč
    • •
  • MZ
Project

Role of heme oxygenase in the pathogenesis of hepatocelular injury in chronic HCV infection (NR9412)

In the presented project, the role of hemooxygenase 1 and 2 in the procesess associated with fibroproduction in the chronic HCV infection will be studied of the chronic HCV infection. Our expected results may help understanding the ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2007 - 2010
    • •
  • 4 641 tis. Kč
    • •
  • 4 467 tis. Kč
    • •
  • MZ
Project

Immunohistochemical detection of predictive factors of response to interferon therapy in patients with chronic hepatitis C (NR7814)

Hepatitis C virus (HCV) related alteration of signalling pathways and proteins (Jak-Stat, ERK1/2, NF-kB, MAP, etc.) regulated/activated by interferon (IFN) may lead to resistance to IFN treatment of patients with HCV infection. ...

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 1 733 tis. Kč
    • •
  • 1 618 tis. Kč
    • •
  • MZ
Project

*Research of the technology for sensitive and quantitative detection of human pathogens - viruses HCV and HBV - and the optimization of appropriate diagnostic process (FI-IM5/042)

*The aim of the project is the research and optimization of technology for detection of two pathogens HCV and HBV by means of polymerase chain reaction (PCR). These viruses cause hepatitis, which is one of the most serious human disease with...

FS - Lékařská zařízení, přístroje a vybavení

  • 2008 - 2010
    • •
  • 18 877 tis. Kč
    • •
  • 8 810 tis. Kč
    • •
  • MPO
Project

In vitro and ex vivo models to study drug-drug interactions of antiviral drugs on intestinal transporters (GJ18-07281Y)

drug transporters. Such compounds are today anti-HIV and anti-HCV drugs that are administered to patients with HIV/HCV co-infections. Combination anti-HIV/anti-HCV therapy......

Pharmacology and pharmacy

  • 2018 - 2022
    • •
  • 4 967 tis. Kč
    • •
  • 4 967 tis. Kč
    • •
  • GA ČR
Project

Subtyping and genotyping of E2 region of HCV in Haemodialyzed Patients pathogenesis and KCV transmission study (IZ3499)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1996 - 1998
    • •
  • 1 660 tis. Kč
    • •
  • 1 660 tis. Kč
    • •
  • MZ
Project

Diagnosis of chronic hepatitis C virus infection by polymerase chain reaction. (IZ2263)

9F - 9

  • 1994 - 1996
    • •
  • 389 tis. Kč
    • •
  • 532 tis. Kč
    • •
  • MZ
Project

Heme Catabolic Pathway in Chronic Hepatitis C (NT13092)

of HMOX is reduced during hepatitis C infection (HCV) in vivo. Biliverdin seems to interfere with HCV replication in vitro. Recently, in the retrospective pilot study, we have found significant association between BVRA expression i...

FP - Ostatní lékařské obory

  • 2012 - 2015
    • •
  • 4 323 tis. Kč
    • •
  • 4 323 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 19