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173 (0,098s) •

Project

The appreciacion of clinical development of opportunistic infection in the relation to immunological profile in HIV+ patients. (IZ2330)

9F - 9

  • 1994 - 1996
    • •
  • 959 tis. Kč
    • •
  • 1 209 tis. Kč
    • •
  • MZ
Project

Identification of some markers of the progression of HIV infection. (IZ3298)

9F - 9

  • 1995 - 1995
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MZ
Project

Monitoring of HIV infection in injecting drug users and prostitutes using the detection of specific antibodies in saliva. (IZ2678)

9F - 9

  • 1995 - 1996
    • •
  • 404 tis. Kč
    • •
  • 404 tis. Kč
    • •
  • MZ
Project

Construction of recombinant mimotopes for induction of neutralizing antibodies against HIV-1 gp120 glycoprotein using high-affinity binders approach (NV15-32198A)

Development of vaccine preventing HIV-1 infection is hindered by high variability of envelope glycoprotein (Env), known target for neutralizing antibodies. Identification of several monoclonal antibodies neutralizing broad range of HIV<...

EC - Imunologie

  • 2015 - 2018
    • •
  • 6 200 tis. Kč
    • •
  • 6 200 tis. Kč
    • •
  • MZ
Project

Monitoring of HIV/AIDS spread in the Czech Republic (NR7843)

HIV/AIDS topic in public health. National monitoring programme, HIV and AIDS reporting system, compatibility with European monitoring programme. HIV/AIDS epidemiology, molecular epidemiology, surveillance in population at h...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2004 - 2006
    • •
  • 8 779 tis. Kč
    • •
  • 6 375 tis. Kč
    • •
  • MZ
Project

TOXOPLASMOSIS AND ASSOCIATED RISKS IN HIV POSITIVE PATIENTS A COHORT STUDY 1988 - 2007 (NR8283)

Latent' toxoplasmic infection in an HIV+ patient represents a possible precursor condition to toxoplasmic encephalitis. Prevalence in the HIV+ and HIV- populations is apparently the same although in HIV+ men it is ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2005 - 2007
    • •
  • 2 065 tis. Kč
    • •
  • 1 335 tis. Kč
    • •
  • MZ
Project

The role of DNA methylation and histone modifications in the establishment and maintenance of HIV-1 latency (GP204/08/P616)

Understanding of molecular mechanisms involved in the HIV latency is critical for eradication of HIV-1 infection. We found that CpG methylation of the HIV-1 promoter in 5?LTR is not needed for establishment of HIV-...

EB - Genetika a molekulární biologie

  • 2008 - 2010
    • •
  • 1 500 tis. Kč
    • •
  • 1 500 tis. Kč
    • •
  • GA ČR
Project

Sensing of HIV-1 by plasmacytoid dendritic cells dichotomy of immunoreceptor signaling (GA14-32547S)

interferon (IFN-I) in human organism, in pathogenesis of HIV-1 infection is not clear. In contrast to HIV-1 infected lymphocytes, HIV-1 virions are weak inducers of IFN-I. Exposure of pDCs to HIV-1-infected lympho...

EE - Mikrobiologie, virologie

  • 2014 - 2018
    • •
  • 6 397 tis. Kč
    • •
  • 6 397 tis. Kč
    • •
  • GA ČR
Project

NEW POSSIBILITIES IN THERAPY OF HIV/AIDS DISEASE ROLE OF HEME OXYGENASE, BILIVERDIN REDUCTASE AND THE EFFECTS OF HEME ARGINATE ON REPLICATION AND REACTIVATION OF HIV-1 (NT14135)

Goals of the project: 1/ To verify and further study effects of HA on HIV-1 HA effect on acute infection of PBMC's of healthy donors with HIV-1 b/ To study HA effect on reactivation of HIV-1 latent infection in PBMC's of

EE - Mikrobiologie, virologie

  • 2013 - 2015
    • •
  • 6 216 tis. Kč
    • •
  • 6 084 tis. Kč
    • •
  • MZ
Project

HIV protease inhibitors mechanism of action and resistance development (GAP207/11/1798)

The development of potent and specific inhibitors of HIV protease (PR prolonged treatment by HIV PR inhibitors, the virus accummulates mutations not only Gag polyprotein. We propose to analyze the development of antiviral HIV

CE - Biochemie

  • 2011 - 2013
    • •
  • 5 522 tis. Kč
    • •
  • 5 522 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 173