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2 225 (0,146s) •

Project

"Tailoring" therapy of chronic viral hepatitis B and C interferonem alfa (IZ4234)

Optimalization of interferon alpha therapy ("tailoring"therapy) in patients with chronic hepatitis B and C using monitoring viremia and detection of hepatitis C virus serotype.......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1997 - 1999
    • •
  • 1 981 tis. Kč
    • •
  • 1 378 tis. Kč
    • •
  • MZ
Project

Sensing of hepatitis B virus-infected hepatocytes by plasmacytoid dendritic cells (GA17-15422S)

The role of plasmacytoid dendritic cells (pDCs), a major source of interferon (IFN) alpha in human organism, in pathogenesis of hepatitis B virus (HBV) infection is not clear. We hypothesize that pDCs could be involved via ...

EE - Mikrobiologie, virologie

  • 2017 - 2021
    • •
  • 7 608 tis. Kč
    • •
  • 6 891 tis. Kč
    • •
  • GA ČR
Project

Identification of novel antiviral targets in the nucleus of hepatitis B virus infected cells (GN24-11554O)

Chronic hepatitis B virus (HBV) infection is a major public health problem affecting approximately 250 million people worldwide. HBV genome forms covalently closed circular DNA (cccDNA) and persists in the nucleus of hepato...

Virology

  • 2024 - 2027
    • •
  • 5 273 tis. Kč
    • •
  • 5 273 tis. Kč
    • •
  • GA ČR
Project

Molecular epidemiology of hepatitis B virus sequencing analysis of the HBV genom as an epidemiological tool (NI6796)

Introduction of sequence analysis of PCR products of HBV isolates. Obtaining principle data about genom variability of HBV DNA isolates and geographic distribution of genotypes and mutants with clinical or epidemiological importance in Czech Republic...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2001 - 2003
    • •
  • 3 679 tis. Kč
    • •
  • 1 556 tis. Kč
    • •
  • MZ
Project

Characterization of porcine gastroenteric viruses as a primary source of environmental and food contamination. (QH81061)

will particularly focus on rotaviruses, coronaviruses, hepatitis E virus, astroviruses and commensal viruses shed into the external environment through faeces of infected pigs of the shed viruses will be important...

EE - Mikrobiologie, virologie

  • 2008 - 2012
    • •
  • 7 534 tis. Kč
    • •
  • 7 089 tis. Kč
    • •
  • MZe
Project

In vitro, in situ and ex vivo study of interactions of novel antiviral agents with drug transporters; effect on their passage across the placenta (GA17-16169S)

Antiviral pharmacotherapy in pregnancy significantly reduces the risk of vertical viral transmission, the most common source of human immunodeficiency virus (HIV), hepatitis B virus (HBV) or hepatitis C

FR - Farmakologie a lékárnická chemie

  • 2017 - 2019
    • •
  • 6 991 tis. Kč
    • •
  • 6 991 tis. Kč
    • •
  • GA ČR
Project

Fuctional diversity of hepatitis C virus quasispecies evaluated by high-throughput analysis of IRES elements activities - implications for the therapy (GA301/07/0607)

Hepatitis C has been recognised during past years as one of the most important viral infectious diseases with estimated number of the infected individuals reaching which can further develop to liver cirrhosis and hepatocellular carcinoma.

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 5 344 tis. Kč
    • •
  • 5 344 tis. Kč
    • •
  • GA ČR
Project

Study of the epidemiology of TT virus by molecular biological methods (GA310/00/1060)

be associated with some cases of virus-induced hepatitis. Since there are no data yet and blood products, there is still arisk of acute and chronic posttransfusion hepatitis with unknown ethiology. In 1997, a novel vir...

EE - Mikrobiologie, virologie

  • 2000 - 2002
    • •
  • 3 789 tis. Kč
    • •
  • 3 170 tis. Kč
    • •
  • GA ČR
Project

Long-term investigation of efficacy of vaccination against hepatitis B in newborns of HBsAg positive mothers. (NI6047)

For long term evaluation of efficacy of vaccination against hepatitis B there is necessary to investigate the development of protective anti- HBs levels and also the appearance of inaparent and clinical infections in vaccinated chil...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2000 - 2002
    • •
  • 1 277 tis. Kč
    • •
  • 1 277 tis. Kč
    • •
  • MZ
Project

Disorder of Porphyprin Metabolism in Patients on regular Hemodialysis and its Association with chronic Hepatitis C virus Infection. (IZ3652)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1996 - 1997
    • •
  • 530 tis. Kč
    • •
  • 514 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 2 225