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5 369 (0,196s) •

Project

Electrophoresis and Western Blotting of IGF I Binding Preoteins in Disorders of the Growth Hormone -IGF-I Axis. (IZ3661)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1996 - 1998
    • •
  • 1 489 tis. Kč
    • •
  • 1 399 tis. Kč
    • •
  • MZ
Project

Towards molecular separation of metabolic and mitogenic effects of insulin and IGF-2 (GA15-19018S)

Insulin and IGF-2 are related hormones that control key aspects of metabolism and growth in tissues. Although insulin and IGF-2 have distinct physiological roles IR-B or IR-A and IGF-1R. Deregulation of receptors leads to t...

CE - Biochemie

  • 2015 - 2017
    • •
  • 6 705 tis. Kč
    • •
  • 6 705 tis. Kč
    • •
  • GA ČR
Project

Analogues of insulin, IGF-1 and IGF-2 to study their neuroprotective effects in neurons and glial cells. (GA22-17978S)

. Broader knowledge of possible positive influence of insulin, IGF-1 or IGF-2 therapies basal and neuroprotective effects of several unique insulin, IGF-1 and IGF-2......

Cell biology

  • 2022 - 2024
    • •
  • 9 928 tis. Kč
    • •
  • 9 017 tis. Kč
    • •
  • GA ČR
Project

Relationship betwween insulin resistance and IGF-1 with respect to the risk of vasculár damage development (NK4751)

The aim is to study the relationship of GH-IGF I axis and IGFBPs in blood and in tissue fluid to parametrs of endothelial activation and marlers of oxidative stress in normals and under pathological circumstances. The project will elucidate ...

FP - Ostatní lékařské obory

  • 1998 - 2000
    • •
  • 1 618 tis. Kč
    • •
  • 1 469 tis. Kč
    • •
  • MZ
Project

The Long-term effect of Low protein diet on growth hormone and IGF-1 in growing ewe (GA523/97/1220)

The present project has been designed to elucidate the effects of long-term restriction of proteins in the diet of growing sheep on markers of growth, i.e. GH and IGF-1 levels in the peripheral blood. Our project is coherent with st...

GH - Výživa hospodářských zvířat

  • 1997 - 1998
    • •
  • 656 tis. Kč
    • •
  • 404 tis. Kč
    • •
  • GA ČR
Project

Prospective study of factors influencing postnatal growth and factors that constitute risk of certain diseases in adulhood in children born small for gestational age and in children with extremely low birth weight (NR9374)

) is associated with low birth weight and low IGF-I levels. Some polymorphism of IGF-I gene correlates with IGF-I levels, decreasing levels of IGF-I according to age and patternof pre - and postnatal growth. The ai...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2007 - 2009
    • •
  • 8 692 tis. Kč
    • •
  • 8 656 tis. Kč
    • •
  • MZ
Project

The metabolic changes during plan surgery procedure period. (NB7561)

The clinical prospective study of monitoring plasmatic metabolic markers changes (IGF-I, cholesterol, apolipoproteins, insulin) during different nutritionalperioperative strategies (parenteral, enteral support and starvation). The aim of the...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
    • •
  • 1 325 tis. Kč
    • •
  • 1 312 tis. Kč
    • •
  • MZ
Project

The Effect of Impaired Nutritional Status in Children and Adolescents on the Metabolism of Orexin A. (NE7443)

in the relationship to serum levels of leptin and IGF-1. To determine the effect of body weight children in the relationship to serum levels of leptin and IGF-1. To determine......

FG - Pediatrie

  • 2003 - 2005
    • •
  • 1 882 tis. Kč
    • •
  • 1 867 tis. Kč
    • •
  • MZ
Project

Improvement of the diagnostics of disorders of growth hormone secretion with the follow- up of growth hormone binding protein and IGF-binding protein 3 (IZ2344)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1994 - 1997
    • •
  • 589 tis. Kč
    • •
  • 706 tis. Kč
    • •
  • MZ
Project

Binding proteins of IGF in hypopituitary patients treated with growth hormone. (NB5458)

IGF I binding proteins, Western Blotting, fragmentation, therapy with growth hormone. The examination of IGF I binding proteins including their low and high molecular forms and proteolytic fragments will contribute to the improvemen...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1999 - 2001
    • •
  • 1 914 tis. Kč
    • •
  • 1 914 tis. Kč
    • •
  • MZ
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