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1 032 (0,077s) •

Project

Physiologically based prediction of pharmacokinetics prior to in vivo studies Focus on hepatic and renal drug elimination (1P05OC061)

possibilities of combined usage of in vitro methods and computational models in silico for prediction of pharmacokinetics in vivo...

FR - Farmakologie a lékárnická chemie

  • 2005 - 2008
    • •
  • 2 526 tis. Kč
    • •
  • 2 526 tis. Kč
    • •
  • MŠMT
Project

In vitro oocyte culture vs in vivo oocyte development - is their physiology really comparable? (GA19-13491S)

of the “in vitro” produced embryos matches that of the embryos developed in vivo and “naturally of translation of specific transcripts between the MII oocytes matured in vitro and in vivo, as well as between the zygotes obtained af...

Reproductive biology (medical aspects to be 3)

  • 2019 - 2022
    • •
  • 8 748 tis. Kč
    • •
  • 8 235 tis. Kč
    • •
  • GA ČR
Project

Estimation of dose from radon progeny by measurements of Pb 210 in vivo and in the environment. (IZ1928)

9F - 9

  • 1994 - 1996
    • •
  • 895 tis. Kč
    • •
  • 1 295 tis. Kč
    • •
  • MZ
Project

Radiosenzitivity of hematopoietic progenitors (CD34+/AC133+) and effect of citokines on expansion ex vivo. (MO66020398129)

Radiosenzitivity of hematopoietic progenitors (CD34+/AC133+) and effect of citokines on expansion ex vivo....

FD - Onkologie a hematologie

  • 1998 - 2000
    • •
  • 643 tis. Kč
    • •
  • 643 tis. Kč
    • •
  • MO
Project

Critical assessment of some current natural products with potential therapeutic applications in liver injuries in vivo and in vitro evaluation (NR9379)

. - The application of several different experimental animal models (in vivo) and cellular models and in vivo approaches is related to the study objectives where findings from in vivo, in vivo studies will be appli...

FR - Farmakologie a lékárnická chemie

  • 2007 - 2009
    • •
  • 2 843 tis. Kč
    • •
  • 2 787 tis. Kč
    • •
  • MZ
Project

Changes in pharmacokinetics and pharmacodynamics of drugs in the presence of impaired liver function (1P05OC062)

introduction of suitable in vivo and in vitro methods for prediction and evaluation of pharmacokinetics and pharmacodynamic properties of substances at hepatic damage......

FR - Farmakologie a lékárnická chemie

  • 2005 - 2008
    • •
  • 2 526 tis. Kč
    • •
  • 2 526 tis. Kč
    • •
  • MŠMT
Project

Interstitial impurities in NiTi-based shape memory alloys (GA15-16336S)

and environments that assist heat treatments and in-vivo applications. We address two opened in-vivo exposures. Thus the attention will also be given to changes in structure and properties of NiTi alloys exposed to in-vivo...

JG - Hutnictví, kovové materiály

  • 2015 - 2018
    • •
  • 6 341 tis. Kč
    • •
  • 6 341 tis. Kč
    • •
  • GA ČR
Project

Effect of antidepressant drugs on the hypothalamo-pituitary-thyroid axis In vivo and in vitro studies of relationship between thyroid function and psychiatric (IZ4204)

The effects of antidepressants on in vivo and in vitro secretory activity of the hypothalamus, anterior pituitary, pineal and thyroid gland, neurotransmitter receptors, the relationship between the HPT axis and antidepressants.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1997 - 1999
    • •
  • 2 221 tis. Kč
    • •
  • 1 733 tis. Kč
    • •
  • MZ
Project

Radiofrequency ablation of pancreas (NS10239)

The purpose of this project is during two-phase ( first phase ex-vivo, second phase in-vivo) experimental study on porcine model, to work up methodics for safe radiofrequency ablation of pancreas, which could be used in human medici...

FJ - Chirurgie včetně transplantologie

  • 2009 - 2011
    • •
  • 4 796 tis. Kč
    • •
  • 4 796 tis. Kč
    • •
  • MZ
Project

EXIT & SIT; EX VIVO TISSUE MODELS FOR SMALL INTESTINE TISSUE (GA25-17718S)

Progress in many scientific areas, such as the safety assessment of different substances, relies on ex vivo reconstituted tissues. Yet, the field of scaffold construction for ex vivo reconstituted intestinal tissues is relatively un...

Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

  • 2025 - 2027
    • •
  • 11 052 tis. Kč
    • •
  • 11 052 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 1 032