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3 (0,089s)

Project

Monitoring of protein network dynamics during sperm-egg membrane interaction (GA18-11275S)

of them (Izumo1, CD9, Juno) were proven to be essential, whereas others were this effort, the egg receptor for sperm primary fusion protein Izumo1 has still not been receptor-like for Izumo1 and confirm its relevance in vi...

Reproductive biology (medical aspects to be 3)

  • 2018 - 2020
  • 7 875 tis. Kč
  • 7 875 tis. Kč
  • GA ČR
Project

The role of FcRL1 and FcRL3 proteins during gamete membrane binding and fusion. (GA22-30494S)

Prior research has identified molecular changes that gametes undergo during fertilization. So far, three main proteins (IZUMO1, CD9 and JUNO) have been known as essential for gamete fusion, whereas the sperm fusion receptor on the oocyte has...

Reproductive biology (medical aspects to be 3)

  • 2022 - 2024
  • 9 474 tis. Kč
  • 9 474 tis. Kč
  • GA ČR
Project

Deciphering crosstalk of protein networks in fertilisation success. (GA25-17315S)

Protein interactions that result in gamete fusion and involve Izumo1, Juno and CD9, have not been fully characterised. Recently, we discovered a human oocyte fusion receptor hFCRL3, named MAIA, which is predicted to facilitate sperm fusion. ...

Reproductive biology (medical aspects to be 3)

  • 2025 - 2027
  • 9 945 tis. Kč
  • 9 945 tis. Kč
  • GA ČR
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