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564 (0,119s) •

Project

Risk of pancreatic karcinoma in patients with chronic pancreatitis (NK6153)

The long-term observation of patients with chronic pancreatitis: establishing the oncomarkers (p53,K-ras,Ca50, state of genes for p53) and oxid.stress markers in the pancreatic tissue,pancreatic juice and blood serum.......

FE - Ostatní obory vnitřního lékařství

  • 2000 - 2002
    • •
  • 1 879 tis. Kč
    • •
  • 1 879 tis. Kč
    • •
  • MZ
Project

K-ras oncogene mutations examination in malignant and non-malignant diseases of pancreas and hepatho-billiar tract (NC4953)

The study is designated to determine sensitivity and specifity of K-ras mutations examined in pancreatic juice of patients with malignant and nonmalignant pancreatic and hepatobilliar diseases. DNA isolation will be carried out by p...

FD - Onkologie a hematologie

  • 1998 - 2000
    • •
  • 357 tis. Kč
    • •
  • 357 tis. Kč
    • •
  • MZ
Project

Detection of activated ras oncogenes in non-small-cell lung carcinoma and in premalignant changes of the respiratory epithelium Use in early diagnosis and prev (IZ2290)

9F - 9

  • 1994 - 1996
    • •
  • 1 570 tis. Kč
    • •
  • 2 260 tis. Kč
    • •
  • MZ
Project

Adjuvant chemotherapy in completely resected K- ras positive lung cancer. (IZ1727)

9F - 9

  • 1993 - 1995
    • •
  • 150 tis. Kč
    • •
  • 300 tis. Kč
    • •
  • MZ
Project

Determination of the prognossis and treatment patients with CRC to find out of the circulated tumor cells in assitance with PCR of the K-ras mutation (NR7884)

to be provided by the detection of tumorous cells circulating in the blood. The presence of K-ras mutation in a large number of patients suffering from colon-rectal carcinoma......

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 2 026 tis. Kč
    • •
  • 1 752 tis. Kč
    • •
  • MZ
Project

The migration of fluids, element redistribution, geochemical and petrophysical changes over the Ždánice hydrocarbon deposit (GA205/03/1256)

The target of the research project is the study of migration of fluids over the Ždánice hydrocarbon deposit, 30 km ESE from Brno, Czech Republic. The study of the distribution of radioactive elements U, Ra, K, Th and Rn is a signifi...

DD - Geochemie

  • 2003 - 2005
    • •
  • 1 472 tis. Kč
    • •
  • 1 472 tis. Kč
    • •
  • GA ČR
Project

Genes involved in XME, DNA repair and cell cycle and their role in predicting risk of laryngeal cancer (NR9423)

analysis of genetic polymorphisms in xenobiotic metabolising enzymes genes, DNA repair genes and cell-cycle genes in PBL of patients and control subjects analysis of molecular epidemiologic parameters of laryngeal cancer gene expresions of DNA repair...

FD - Onkologie a hematologie

  • 2007 - 2009
    • •
  • 6 260 tis. Kč
    • •
  • 5 908 tis. Kč
    • •
  • MZ
Project

Be The Cure (7H12093)

The development of new therapeutic agents against RA and RA-like diseases; (2) the heterogeneous nature of human RA and RA-like diseases; (3) the need for new alignments between several animal models and the varian...

FE - Ostatní obory vnitřního lékařství

  • 2012 - 2016
    • •
  • 9 375 tis. Kč
    • •
  • 2 296 tis. Kč
    • •
  • MŠMT
Project

The prediction of development of rheumatoid arthritis (NU22-05-00226)

Rheumatoid arthritis (RA) is a chronic autoimmune disease considered (ACPA) and rheumatoid factors (RF) preceding the manifestation of RA by months to years. Despite the typical joint involvement in RA, the pathogenesis lik...

Rheumatology

  • 2022 - 2025
    • •
  • 8 572 tis. Kč
    • •
  • 8 572 tis. Kč
    • •
  • MZ
Project

Role of a novel cytokine IL-40 in the pathogenesis of rheumatoid arthritis (NU21-05-00276)

in the synovial tissue and in the serum of patients with established rheumatoid arthritis (RA are enhanced and play a key role at the onset of RA, we believe that IL-40 is involved in the early phases of RA development. Th...

Rheumatology

  • 2021 - 2024
    • •
  • 9 430 tis. Kč
    • •
  • 9 430 tis. Kč
    • •
  • MZ
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