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4 624 (0,148s) •

Project

The influence of L-arginine and its analogues on the generation of reactive oxygen and nitrogen species by professional phagocytes (GA524/08/1753)

The aim of the project is to determine the effects of L-arginine and its analogues on the activity of NADPH oxidase, myeloperoxidase and inducible nitric oxide synthase. The activity of enzymes will be analysed in: i) ?chemical? sys...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2008 - 2012
    • •
  • 4 969 tis. Kč
    • •
  • 4 969 tis. Kč
    • •
  • GA ČR
Project

Interactions among collagen, platelets and phagocytes in modulation of reactive oxygen and nitrogen species production (OC10044)

to modulate the oxidative burst of phagocytes, production of reactive oxygen and nitrogen species by phagocytes and the extent of oxidative stress under pathological conditions adenosine and 5-hy...

EC - Imunologie

  • 2010 - 2011
    • •
  • 742 tis. Kč
    • •
  • 742 tis. Kč
    • •
  • MŠMT
Project

Effects of polyunsaturated fatty acids and their metabolites on the physiological functions of professional phagocytes (OC08058)

acids (PUFA) on the intra- and extracellular generation of reactive oxygen and nitrogen species (RONS) by resting and activated phagocytes, to investigate effects of phagocytes stimulated with co...

ED - Fyziologie

  • 2008 - 2010
    • •
  • 1 608 tis. Kč
    • •
  • 1 608 tis. Kč
    • •
  • MŠMT
Project

Reactive oxygen and nitrogen metabolites generated by neutrophils under physiological and pathological conditions (GA524/00/1223)

of neutrophil-derived reactive oxygen metabolites (ROM) and reactive nitrogen metabolites reactive oxygenand reactive nitrogen metabolites measurement ii) to define precisely the employm...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2000 - 2002
    • •
  • 2 581 tis. Kč
    • •
  • 1 943 tis. Kč
    • •
  • GA ČR
Project

Molecular biological perspectives of the pharmacological modulation of the activation of professional phagocytes (MEB0810013)

Activation of tissue and blood phagocytes results in a production of reactive oxygen species during the oxidative stress. The response of professional phagocytes after their activation may be diminished by...

FR - Farmakologie a lékárnická chemie

  • 2010 - 2011
    • •
  • 86 tis. Kč
    • •
  • 86 tis. Kč
    • •
  • MŠMT
Project

Interactions between collagen, platelets and neutrophils with respect to wound healing (GA524/07/1511)

or not reactive oxygen and nitrogen species produced by professional phagocytes could modify that a phagocyte- derived oxidative stress could occur and participate in the pathophysiology, platele...

EC - Imunologie

  • 2007 - 2009
    • •
  • 3 013 tis. Kč
    • •
  • 3 013 tis. Kč
    • •
  • GA ČR
Project

Role of reactive nitrogen and oxygen species in signaling pathways and responses of honey bees to stress conditions (LTAUSA17116)

The aim of the project is to obtain new knowledge on the role of nitric oxide (NO) and reactive nitrogen and oxygen species (RNS, ROS) in signaling pathways regulating responses and defense mechanisms of honey bees...

CE - Biochemie

  • 2017 - 2021
    • •
  • 3 784 tis. Kč
    • •
  • 3 784 tis. Kč
    • •
  • MŠMT
Project

The role of serotonin in mutual interactions of platelets and professional phagocytes (GA524/04/0897)

: The antioxidative properties of serotonin against individual reactive oxygen and nitrogen species will be tested using various chemical systems. hiteractions between serotonin of mutual interactions between plate...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2004 - 2006
    • •
  • 2 359 tis. Kč
    • •
  • 2 359 tis. Kč
    • •
  • GA ČR
Project

The role of oxygen metabolites and nitric oxide in the development of intestinal reperfusion injury (GA308/97/1141)

The main objective of the project is to provide new information on the pathomechanisms triggered by reactive oxygen species and nitric oxide on a model of oxygen and nitrogen mediators, migration and metab...

FI - Traumatologie a ortopedie

  • 1997 - 1999
    • •
  • 3 496 tis. Kč
    • •
  • 1 767 tis. Kč
    • •
  • GA ČR
Project

New Role for Nitrated Fatty Acid in Modulation of Phagocyte-derived Inflammatory Responses (GP13-40824P)

-FAs to the phagocyte and endothelial cell alterations that are characteristic of phagocyte-derived inflammation and endothelial dysfunction related to these processes. Attention will be mainly directed toward how the NO2-FAs exert ...

EC - Imunologie

  • 2013 - 2016
    • •
  • 2 471 tis. Kč
    • •
  • 2 471 tis. Kč
    • •
  • GA ČR
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