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141 (0,103s) •

Project

HDL and LDL lipoprotein subpopulations and fibrinogen influenced by diet with alcohol (NA6590)

Effect of moderate drinking of Moravian white wine and red wine for 4 weeks on HDL and LDL lipoprotein subpopulations, cholesterol esterification and fibrinogen will be studied in 50 men.......

FQ - Veřejné zdravotnictví, sociální lékařství

  • 2001 - 2003
    • •
  • 1 567 tis. Kč
    • •
  • 1 558 tis. Kč
    • •
  • MZ
Project

Lipoperoxidation, LDL composition and risk of cardiovascular diseases. (IZ3596)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1996 - 1998
    • •
  • 1 001 tis. Kč
    • •
  • 979 tis. Kč
    • •
  • MZ
Project

Small size LDL particles as a new risk of premature atherosclerosis (IZ3075)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1995 - 1997
    • •
  • 575 tis. Kč
    • •
  • 531 tis. Kč
    • •
  • MZ
Project

Influence of oxidative modification of proteins on activation of human blood platelets (NK6841)

The aim of the project is to find if oxidized LDL and/or oxidized fibrinogen generated during activation of platelets will be detected. LDL from normal donors will be estimated by several independent methods. Native LDL and...

FP - Ostatní lékařské obory

  • 2001 - 2003
    • •
  • 2 178 tis. Kč
    • •
  • 2 100 tis. Kč
    • •
  • MZ
Project

LDL gene score in the diagnosis of primary hypercholesterolemias and cardiovascular risk assessment (NV15-28277A)

Familial hypercholesterolemia (FH) is autosomal dominant disorder caused mostly by mutations in the LDL-receptor gene or the the gene encoding for apolipoprotein B levels (LDL polygenic score). The phenotype and the risk of complica...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2015 - 2018
    • •
  • 9 760 tis. Kč
    • •
  • 9 760 tis. Kč
    • •
  • MZ
Project

Proprotein convertase subtilisin/kexin 9 (PCSK9) in the pathophysiology a treatment of dry age-related macular degeneration (NV17-29241A)

of cell surface low density lipoprotein (LDL) cholesterol receptor levels. Decrease that rheohemapheresis also reduces plasma PCSK9 levels by removing LDL cholesterol. The PCSK9 level of LDL receptor function and LDL

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2017 - 2020
    • •
  • 9 814 tis. Kč
    • •
  • 9 814 tis. Kč
    • •
  • MZ
Project

Evaluation of effectiveness of the short-term LDL apheresis treatment in patients with hyperlipoproteinemia and coronary artery disease. (NB6134)

Evaluation of efficacy of short term LDL-apheresis in patients with hyperlipidaemia and ischaemic heart disease with accelerated angina pectoris in pre-treatment period that is not manageable by revascularisation procedures and also in patie...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2000 - 2002
    • •
  • 3 010 tis. Kč
    • •
  • 2 011 tis. Kč
    • •
  • MZ
Project

Prediction, optimation and individualization of therapeutic procedure in LDL-apheresis - a multivariate model in a prospective study. (NB7006)

The project objectives are to define the most important factors influencing the speed and economy of LDL-aphereses, therapeutic results (substantial reduction of LDL-cholesterol) under conditions of minimal patient´s discomfort. The...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2002 - 2004
    • •
  • 1 493 tis. Kč
    • •
  • 1 490 tis. Kč
    • •
  • MZ
Project

The effect of acute hyperinsulinaemia on susceptibility to oxidation and fatty acid composition of low-density lipoprotein in the offspring of hypertensive pare (NB4888)

The aim of the study is to compare the susceptibility to oxidation and fatty acid compostion of LDL in the offsprig of hypertensive parents and subjects of acutely induced hyperinsulinaemia on LDL oxidability and the fatty acid patt...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1998 - 2000
    • •
  • 2 148 tis. Kč
    • •
  • 1 804 tis. Kč
    • •
  • MZ
Project

The role of phenotype and genotype of familial hyperlipoproteinaemia in atherogenesis of coronary artery disease. (NB5205)

genotype, 4. LDL - receptor genotype, 5. LDL - receptor activity....

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1999 - 2001
    • •
  • 2 283 tis. Kč
    • •
  • 2 283 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 141