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8 (0,074s) •

Project

Study of predisposing genetic factors in breast cancer (NC7527)

, direct suquencing, LOH analysis....

FD - Onkologie a hematologie

  • 2003 - 2005
    • •
  • 4 155 tis. Kč
    • •
  • 2 479 tis. Kč
    • •
  • MZ
Project

Microsatellite Instability and Loss of Heterozygosity of Specific Genes in Hematological Malignancies. (IZ3567)

FD - Onkologie a hematologie

  • 1996 - 1998
    • •
  • 1 764 tis. Kč
    • •
  • 1 764 tis. Kč
    • •
  • MZ
Project

Role of dominant susceptibility genes in breast tumorigenesis - RNA-based analyses (NR9051)

breast tumors will be analyzed for LOH at respective loci and samples...

FD - Onkologie a hematologie

  • 2006 - 2008
    • •
  • 2 936 tis. Kč
    • •
  • 2 808 tis. Kč
    • •
  • MZ
Project

Genes involved in XME, DNA repair and cell cycle and their role in predicting risk of laryngeal cancer (NR9423)

, Tp53 tumour supressor gene and MSI and LOH in mismatch repair genes in tumour...

FD - Onkologie a hematologie

  • 2007 - 2009
    • •
  • 6 260 tis. Kč
    • •
  • 5 908 tis. Kč
    • •
  • MZ
Project

The study of mech.of proto-oncog.activ.and tumor supressor genes inactiv.by fluresc.in situ hybridiz.(FISH)and compar. genomic hybridiz.(CGH)in pat.with non-Hodgkinś lymph.(NHL). (NC6209)

by FISH with gene specific probes Following of lost of heterozygozity (LOH) for p53...

FD - Onkologie a hematologie

  • 2000 - 2002
    • •
  • 2 582 tis. Kč
    • •
  • 2 571 tis. Kč
    • •
  • MZ
Project

Molecular characteristics of borderline ovarian tumors in relation to their biological behavior (NS10566)

This proposal is designed as a retrospective study analyzing molecular characteristics of borderline ovarian tumors and comparing these characteristics to biological behavior of tumors. We will study frequency and modalities of inactivation of certai...

FK - Gynekologie a porodnictví

  • 2009 - 2011
    • •
  • 4 935 tis. Kč
    • •
  • 4 815 tis. Kč
    • •
  • MZ
Project

Asexuality as bridge towards polyploidy evolution of genome and genotype-by-environment interactions under clonality (GA21-25185S)

Hybridization and polyploidization may open unique opportunities for speciation and the occupation of novel environments. Subgenomes from the original parental species undergo considerable changes in a hybrid, often with preferential elimination of o...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2021 - 2023
    • •
  • 9 929 tis. Kč
    • •
  • 9 929 tis. Kč
    • •
  • GA ČR
Project

A role of hereditary mutations of the PALB2 gene in breast, ovarian and pancreatic cancer development in the Czech Republic (NT14006)

evaluated. Inactivation of wild-type allele in a tumor tissue using LOH analysis...

FD - Onkologie a hematologie

  • 2013 - 2015
    • •
  • 4 440 tis. Kč
    • •
  • 4 440 tis. Kč
    • •
  • MZ
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